Aganglionic megacolon

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Aganglionic megacolon
TermAganglionic megacolon
Short definitionaganglionic megacolon (ay-GANG-joy-AH-nik MEH-guh-KOH-lun) A condition in which certain nerve cells are missing in the muscular layers of part of the colon. This leads to severe constipation or blockage of the colon. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


aganglionic megacolon - (pronounced) (ay-GANG-joy-AH-nik MEH-guh-KOH-lun) A condition in which certain nerve cells are missing in the muscular layers of part of the colon. This leads to severe constipation or blockage of the colon. Constipation is when stools are hard, dry, and difficult to pass, and bowel movements occur less frequently than normal. Other symptoms include a swollen abdomen, vomiting, bloody diarrhea, bloating, lack of energy, and difficulty gaining weight. An aganglionic megacolon is present from birth, but symptoms may not appear until later in a child's life. This condition has been linked to an increased risk of thyroid cancer and neuroblastoma. Also called Hirschsprung disease

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