7-APB

Chemical compound related to MDMA

7-APB
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7-APB (7-(2-aminopropyl)benzofuran) is a synthetic chemical compound that is structurally related to MDMA and other members of the benzofuran class. It is known for its psychoactive effects and has been used as a designer drug.

Chemical structure and properties

Structural formula of 7-APB

7-APB is a member of the benzofuran class of compounds, which are characterized by a benzene ring fused to a furan ring. The chemical structure of 7-APB includes a benzofuran moiety attached to an aminopropyl group. This structure is similar to that of MDMA, with the primary difference being the presence of the benzofuran ring instead of the methylenedioxyphenyl group found in MDMA.

The molecular formula of 7-APB is C11H13NO2, and it has a molar mass of 191.23 g/mol. The compound is typically encountered as a white powder or crystalline solid.

Pharmacology

7-APB acts as a serotonin-norepinephrine-dopamine releasing agent (SNDRA), meaning it increases the levels of these neurotransmitters in the brain. This action is similar to that of MDMA, which is known for its empathogenic and stimulant effects. Users of 7-APB report effects such as euphoria, increased sociability, and enhanced sensory perception.

The compound's effects are believed to result from its ability to release serotonin, norepinephrine, and dopamine, which are neurotransmitters involved in mood regulation, arousal, and reward pathways.

Legal status

The legal status of 7-APB varies by country. In some jurisdictions, it is classified as a controlled substance due to its structural similarity to MDMA and its potential for abuse. In other regions, it may be available as a research chemical or "legal high."

Safety and toxicity

The safety profile of 7-APB is not well-established, as it has not been extensively studied in humans. However, due to its similarity to MDMA, it is likely to share some of the same risks, including potential neurotoxicity, cardiovascular effects, and the risk of serotonin syndrome when combined with other serotonergic substances.

Related compounds

7-APB is part of a broader class of benzofuran derivatives, which includes other compounds such as 5-APB and 6-APB. These compounds share similar structures and pharmacological effects, but differ in the position of the aminopropyl group on the benzofuran ring.

Related pages

• MDMA
• Benzofuran
• Serotonin-norepinephrine-dopamine releasing agent
• Designer drug