4-Amino-3-methyl-1-naphthol

From WikiMD's medical encyclopedia

4-Amino-3-methyl-1-naphthol is a chemical compound with the molecular formula C11H11NO. It is a derivative of naphthol, which is a type of phenol that is derived from naphthalene.

Structure and Properties

The structure of 4-Amino-3-methyl-1-naphthol consists of a naphthalene ring, which is a polycyclic aromatic hydrocarbon composed of two fused benzene rings. Attached to this ring are a methyl group at the 3-position, an amino group at the 4-position, and a hydroxyl group at the 1-position.

This compound exhibits properties typical of both phenols and amines. The presence of the hydroxyl group gives it the ability to form hydrogen bonds, which can affect its solubility in various solvents. The amino group can participate in acid-base reactions, acting as a base by accepting a proton.

Synthesis

The synthesis of 4-Amino-3-methyl-1-naphthol can be achieved through a multi-step process. The starting material is typically naphthalene, which is first methylated to produce 3-methylnaphthalene. This is then nitrated to introduce the amino group, and finally reduced to convert the nitro group to an amino group.

Applications

4-Amino-3-methyl-1-naphthol is primarily used in the synthesis of other chemical compounds. It can serve as a building block in the production of various dyes, pigments, and pharmaceuticals.

Safety and Precautions

As with many chemical compounds, handling 4-Amino-3-methyl-1-naphthol requires certain safety precautions. It is important to avoid contact with skin and eyes, and to use appropriate personal protective equipment when handling this compound.

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Contributors: Prab R. Tumpati, MD