Hydroxy group

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Hydroxy Group

3D model of a hydroxy group

A hydroxy group is a functional group consisting of an oxygen atom covalently bonded to a hydrogen atom. It is represented by the chemical formula -OH. The hydroxy group is a characteristic component of alcohols and phenols, and it plays a crucial role in the chemistry of many organic compounds.

Structure and Properties

The hydroxy group is polar due to the difference in electronegativity between the oxygen and hydrogen atoms. This polarity allows hydroxy groups to form hydrogen bonds with other molecules, which significantly affects the physical properties of compounds containing them, such as boiling point and solubility in water.

Occurrence

Hydroxy groups are found in a wide variety of chemical compounds. They are present in simple alcohols like methanol and ethanol, as well as in more complex molecules such as carbohydrates and amino acids. The presence of hydroxy groups in these compounds is often critical to their biological function.

Chemical Reactions

Hydroxy groups can participate in a variety of chemical reactions. They can act as nucleophiles in substitution reactions, and they can be deprotonated to form alkoxide ions, which are strong bases. Hydroxy groups can also undergo oxidation to form carbonyl groups, such as in the conversion of alcohols to aldehydes or ketones.

Applications

Compounds containing hydroxy groups have numerous applications in industry and medicine. For example, ethanol is widely used as a solvent and in alcoholic beverages, while glycerol is used in pharmaceuticals and cosmetics. Hydroxy groups are also important in the synthesis of polymers and other materials.

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Contributors: Prab R. Tumpati, MD