3F-PVP

Synthetic stimulant drug

3F-PVP
[[File: 3F-PVP chemical structure |frameless|220px|alt=|]]
INN
Drug class
Routes of administration
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status
CAS Number
PubChem
DrugBank
ChemSpider
KEGG

3F-PVP (3-Fluoro-α-pyrrolidinopentiophenone) is a synthetic stimulant of the cathinone class that has been sold online as a designer drug. It is a fluorinated derivative of α-PVP (alpha-Pyrrolidinopentiophenone).

Chemical structure and properties

3F-PVP is chemically similar to α-PVP, differing by the addition of a fluorine atom at the para position of the phenyl ring. The chemical formula is C₁₅H₂₀FNO, and it has a molar mass of 249.33 g/mol. The presence of the fluorine atom is thought to influence the compound's pharmacological properties, potentially affecting its potency and duration of action.

Pharmacology

3F-PVP acts as a norepinephrine-dopamine reuptake inhibitor (NDRI), similar to other synthetic cathinones. This mechanism of action leads to increased concentrations of the neurotransmitters dopamine and norepinephrine in the synaptic cleft, resulting in stimulant effects. Users report effects such as increased alertness, euphoria, and enhanced focus.

Usage and effects

3F-PVP is typically encountered in the form of a white crystalline powder and is often consumed by insufflation, oral ingestion, or vaporization. The effects of 3F-PVP are reported to be similar to those of other synthetic cathinones, with a rapid onset and a duration of action that can last several hours. Common effects include:

• Euphoria
• Increased energy and alertness
• Enhanced sociability
• Increased heart rate and blood pressure

Adverse effects

The use of 3F-PVP can lead to a range of adverse effects, particularly at higher doses or with prolonged use. These may include:

• Anxiety and paranoia
• Insomnia
• Increased risk of cardiovascular events
• Potential for addiction and dependence

Legal status

The legal status of 3F-PVP varies by country. In some jurisdictions, it is classified as a controlled substance due to its structural similarity to other banned synthetic cathinones. In others, it may be considered a "research chemical" and not explicitly regulated, although this status can change rapidly as new legislation is enacted.

Related pages

• Synthetic cathinones
• Designer drugs
• Norepinephrine-dopamine reuptake inhibitor