2F-MAR

Chemical compound

2F-MAR
INN
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CAS Number	849231-30-5
PubChem	119025
DrugBank
ChemSpider	106282
KEGG

2F-MAR (also known as 2'-Fluoro-4-methylaminorex) is a stimulant drug of the aminorex class. It is a designer drug that has been sold online as a research chemical.

Chemical structure and properties

Chemical structure of 2F-MAR

2F-MAR is a derivative of 4-methylaminorex, where the 2' position of the phenyl ring is substituted with a fluorine atom. This modification is thought to influence the compound's pharmacokinetics and pharmacodynamics, potentially altering its potency and duration of action compared to its parent compound.

The chemical structure of 2F-MAR is characterized by the presence of a phenyl ring, a methylamino group, and a ketone group. The addition of the fluorine atom is believed to enhance the compound's ability to cross the blood-brain barrier, thereby increasing its central nervous system activity.

Pharmacology

2F-MAR acts as a central nervous system stimulant. It is thought to exert its effects primarily by increasing the levels of neurotransmitters such as dopamine, norepinephrine, and serotonin in the brain. This is achieved through the inhibition of their reuptake and possibly by promoting their release.

The stimulant effects of 2F-MAR can lead to increased alertness, energy, and euphoria. However, these effects are also associated with potential adverse effects such as anxiety, paranoia, and insomnia.

Legal status

The legal status of 2F-MAR varies by country. In some jurisdictions, it may be classified as a controlled substance due to its structural similarity to other regulated stimulants. In others, it may be considered a new psychoactive substance and subject to specific regulations.

Safety and toxicity

The safety profile of 2F-MAR is not well-established, as it is a relatively new compound with limited research. Potential risks include cardiovascular effects such as increased heart rate and blood pressure, as well as neurotoxicity with prolonged use. Users should exercise caution and be aware of the potential for addiction and overdose.

Related pages

• Aminorex
• 4-Methylaminorex
• Stimulant
• Research chemical