Ethinylestradiol benzoate
Ethinylestradiol benzoate is a synthetic, steroidal estrogen that is derived from estradiol. It is a long-acting estrogen, and is an estrogen ester, specifically, the 3-benzoate ester of ethinylestradiol. Ethinylestradiol benzoate is used in medicine for hormone therapy.
Pharmacology
As a form of estrogen, ethinylestradiol benzoate binds to and activates the estrogen receptor, a type of nuclear receptor that is activated by the hormone estrogen. This results in changes in gene expression which can lead to a variety of effects, including the development of female secondary sexual characteristics and the regulation of the menstrual cycle.
Medical uses
Ethinylestradiol benzoate is used in hormone therapy for menopausal symptoms, hypogonadism, prostate cancer, and for other conditions. It is also used in hormonal contraception, specifically in combination with a progestogen.
Side effects
Like all estrogens, ethinylestradiol benzoate has a number of potential side effects. These can include nausea, breast tenderness, fluid retention, and an increased risk of thrombosis. It can also cause changes in mood and libido.
See also
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