Hypercalcaemia

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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| Hypercalcaemia | |
|---|---|
| Calcium | |
| Synonyms | Hypercalcemia |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Nausea, vomiting, abdominal pain, muscle weakness, confusion, fatigue |
| Complications | Kidney stones, osteoporosis, cardiac arrhythmias, renal failure |
| Onset | Can be acute or chronic |
| Duration | Varies depending on cause |
| Types | N/A |
| Causes | Hyperparathyroidism, cancer, sarcoidosis, vitamin D intoxication, medications |
| Risks | Dehydration, immobility, family history |
| Diagnosis | Blood test showing elevated calcium levels |
| Differential diagnosis | Hyperthyroidism, adrenal insufficiency, multiple myeloma |
| Prevention | Adequate hydration, monitoring in at-risk individuals |
| Treatment | IV fluids, bisphosphonates, calcitonin, dialysis |
| Medication | N/A |
| Prognosis | Depends on underlying cause and treatment |
| Frequency | Common in hospitalized patients |
| Deaths | N/A |
Hypercalcaemia is a condition characterized by an abnormally high level of calcium in the blood. It is most commonly a result of overactive parathyroid glands. Other causes include cancer, certain medications, and excessive intake of vitamin D or calcium.
Causes
Hypercalcaemia can be caused by various conditions, including:
- Hyperparathyroidism: This is the most common cause of hypercalcaemia. The parathyroid glands produce too much parathyroid hormone, which leads to increased levels of calcium in the blood.
- Cancer: Certain types of cancer can cause hypercalcaemia, including lung cancer, breast cancer, and multiple myeloma.
- Medications: Some medications can cause hypercalcaemia, such as lithium and certain diuretics.
- Vitamin D or calcium overdose: Consuming excessive amounts of vitamin D or calcium can lead to hypercalcaemia.
Symptoms
The symptoms of hypercalcaemia can vary depending on the severity of the condition. They may include:
- Fatigue
- Nausea and vomiting
- Constipation
- Excessive thirst and frequent urination
- Confusion or memory loss
- Muscle weakness
- Bone pain
Diagnosis
Hypercalcaemia is typically diagnosed through a blood test that measures the level of calcium in the blood. Additional tests may be performed to determine the underlying cause of the condition.
Treatment
Treatment for hypercalcaemia depends on the underlying cause and the severity of the condition. It may include:
- Intravenous fluids: This can help to lower calcium levels and prevent dehydration.
- Medications: Certain medications can help to lower calcium levels, such as bisphosphonates and calcitonin.
- Surgery: In some cases, surgery may be necessary to remove the overactive parathyroid glands.
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