Keratosis pilaris: Difference between revisions

From WikiMD's Wellness Encyclopedia

No edit summary
 
CSV import
 
Line 1: Line 1:
{{SI}}
{{Infobox medical condition
| name            = Keratosis pilaris
| image          = [[File:Keratosis_pilaris_(moderate).jpg|250px]]
| caption        = Keratosis pilaris on the upper arm
| synonyms        = Follicular keratosis, lichen pilaris
| field          = [[Dermatology]]
| symptoms        = Small, rough bumps on the skin, often on the upper arms, thighs, cheeks, or buttocks
| complications  = [[Dry skin]], [[itching]]
| onset          = Childhood
| duration        = Long-term
| causes          = [[Keratin]] buildup in hair follicles
| risks          = [[Atopic dermatitis]], [[ichthyosis vulgaris]], [[obesity]], [[asthma]]
| diagnosis      = [[Clinical diagnosis]]
| differential    = [[Acne]], [[folliculitis]], [[milia]]
| treatment      = [[Moisturizers]], [[exfoliation]], [[topical retinoids]]
| medication      = [[Urea]], [[lactic acid]], [[salicylic acid]]
| frequency      = Common
}}
'''Keratosis pilaris''' is a common, benign skin condition characterized by the presence of hard, conical elevations or ''papules'' at the openings of sebaceous glands, primarily on the upper arms and thighs. These rough-feeling bumps, often described as chicken skin, occur as a result of an excess buildup of the skin protein keratin<ref>{{Cite journal|last1=|first1=|title=Keratosis Pilaris: A Common Follicular Hyperkeratosis|journal=|volume=|issue=|pages=|year=|doi=|pmid=}}</ref>.
'''Keratosis pilaris''' is a common, benign skin condition characterized by the presence of hard, conical elevations or ''papules'' at the openings of sebaceous glands, primarily on the upper arms and thighs. These rough-feeling bumps, often described as chicken skin, occur as a result of an excess buildup of the skin protein keratin<ref>{{Cite journal|last1=|first1=|title=Keratosis Pilaris: A Common Follicular Hyperkeratosis|journal=|volume=|issue=|pages=|year=|doi=|pmid=}}</ref>.
[[File:Keratosis Pilaris on Lower Extremity.jpg|thumb|Keratosis Pilaris on Lower Extremity]]
[[File:Keratosis Pilaris on Lower Extremity.jpg|left|thumb|Keratosis Pilaris on Lower Extremity]]
== Clinical Presentation ==
== Clinical Presentation ==
[[File:Keratosis pilaris arm.jpg|thumb|Keratosis pilaris arm]]
[[File:Keratosis pilaris arm.jpg|left|thumb|Keratosis pilaris arm]]
[[File:Keratosis pilaris (moderate).jpg|thumb|Keratosis pilaris (moderate)]]
Patients with keratosis pilaris typically present with numerous tiny, rough, flesh-colored or reddish bumps, often with surrounding erythema. While the condition can occur at any age, it most commonly begins in childhood and improves with age, often disappearing entirely in adulthood. The areas most often affected are the extensor aspects of the upper arms and thighs, although the buttocks and face (particularly the cheeks) may also be involved<ref>{{Cite journal|last1=|first1=|title=Keratosis pilaris revisited: is it more than just a follicular keratosis?|journal=|volume=|issue=|pages=|year=|doi=|pmid=}}</ref>.
Patients with keratosis pilaris typically present with numerous tiny, rough, flesh-colored or reddish bumps, often with surrounding erythema. While the condition can occur at any age, it most commonly begins in childhood and improves with age, often disappearing entirely in adulthood. The areas most often affected are the extensor aspects of the upper arms and thighs, although the buttocks and face (particularly the cheeks) may also be involved<ref>{{Cite journal|last1=|first1=|title=Keratosis pilaris revisited: is it more than just a follicular keratosis?|journal=|volume=|issue=|pages=|year=|doi=|pmid=}}</ref>.
== Pathophysiology ==
== Pathophysiology ==
 
The primary event in keratosis pilaris is hyperkeratosis, an increase in the skin's keratin—a structural protein—around the hair follicles. This buildup leads to the characteristic rough patches and skin-colored bumps associated with the condition. Although the exact reason why keratin buildup occurs isn't known, it may be associated with other skin conditions like atopic dermatitis and genetic diseases<ref>{{Cite journal|last1=|first1=|title=Keratosis pilaris and prevalence of acne vulgaris: a cross-sectional study|journal=|volume=|issue=|pages=|year=|doi=|pmid=}}</ref>.
The primary event in keratosis pilaris is hyperkeratosis, an increase in the skin's keratin—a structural protein—around the hair follicles. This buildup leads to the characteristic rough patches and skin-colored bumps associated with the condition. Although the exact reason why keratin buildup occurs isn't known, it may be associated with other skin conditions like atopic dermatitis and genetic diseases<ref>{{Cite journal|last1=|first1=|title=Keratosis pilaris and prevalence of acne vulgaris: a cross-sectional study|journal=|volume=|issue=|pages=|year=|doi=|pmid=}}</ref>.
 
== Treatment ==
== Treatment ==
Treatment of keratosis pilaris is not medically necessary; however, individuals may desire treatment due to cosmetic concerns or discomfort. Management primarily involves regular application of moisturizers, especially those containing urea, lactic acid, or salicylic acid, which can help to exfoliate and soften the skin. More severe cases may warrant treatment with retinoid creams, which are derivatives of vitamin A that promote cell turnover and prevent the plugging of hair follicles<ref>{{Cite journal|last1=|first1=|title=Keratosis pilaris and its subtypes: associations, new molecular and pharmacologic etiologies, and therapeutic options|journal=|volume=|issue=|pages=|year=|doi=|pmid=}}</ref>.
Treatment of keratosis pilaris is not medically necessary; however, individuals may desire treatment due to cosmetic concerns or discomfort. Management primarily involves regular application of moisturizers, especially those containing urea, lactic acid, or salicylic acid, which can help to exfoliate and soften the skin. More severe cases may warrant treatment with retinoid creams, which are derivatives of vitamin A that promote cell turnover and prevent the plugging of hair follicles<ref>{{Cite journal|last1=|first1=|title=Keratosis pilaris and its subtypes: associations, new molecular and pharmacologic etiologies, and therapeutic options|journal=|volume=|issue=|pages=|year=|doi=|pmid=}}</ref>.
== See Also ==
== See Also ==
* [[Dermatology]]
* [[Dermatology]]
* [[Atopic dermatitis]]
* [[Atopic dermatitis]]
Line 21: Line 33:
== References ==
== References ==
<references />
<references />
[[Category:Dermatology]]
[[Category:Dermatology]]
[[Category:Skin conditions]]
[[Category:Skin conditions]]
[[Category:Noninfectious diseases]]
[[Category:Noninfectious diseases]]
{{Stub}}
{{Stub}}

Latest revision as of 00:42, 8 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Keratosis pilaris
Synonyms Follicular keratosis, lichen pilaris
Pronounce N/A
Specialty N/A
Symptoms Small, rough bumps on the skin, often on the upper arms, thighs, cheeks, or buttocks
Complications Dry skin, itching
Onset Childhood
Duration Long-term
Types N/A
Causes Keratin buildup in hair follicles
Risks Atopic dermatitis, ichthyosis vulgaris, obesity, asthma
Diagnosis Clinical diagnosis
Differential diagnosis Acne, folliculitis, milia
Prevention N/A
Treatment Moisturizers, exfoliation, topical retinoids
Medication Urea, lactic acid, salicylic acid
Prognosis N/A
Frequency Common
Deaths N/A


Keratosis pilaris is a common, benign skin condition characterized by the presence of hard, conical elevations or papules at the openings of sebaceous glands, primarily on the upper arms and thighs. These rough-feeling bumps, often described as chicken skin, occur as a result of an excess buildup of the skin protein keratin<ref>,

 Keratosis Pilaris: A Common Follicular Hyperkeratosis, 
 ,</ref>.
Keratosis Pilaris on Lower Extremity

Clinical Presentation[edit]

Keratosis pilaris arm

Patients with keratosis pilaris typically present with numerous tiny, rough, flesh-colored or reddish bumps, often with surrounding erythema. While the condition can occur at any age, it most commonly begins in childhood and improves with age, often disappearing entirely in adulthood. The areas most often affected are the extensor aspects of the upper arms and thighs, although the buttocks and face (particularly the cheeks) may also be involved<ref>,

 Keratosis pilaris revisited: is it more than just a follicular keratosis?, 
 ,</ref>.

Pathophysiology[edit]

The primary event in keratosis pilaris is hyperkeratosis, an increase in the skin's keratin—a structural protein—around the hair follicles. This buildup leads to the characteristic rough patches and skin-colored bumps associated with the condition. Although the exact reason why keratin buildup occurs isn't known, it may be associated with other skin conditions like atopic dermatitis and genetic diseases<ref>,

 Keratosis pilaris and prevalence of acne vulgaris: a cross-sectional study, 
 ,</ref>.

Treatment[edit]

Treatment of keratosis pilaris is not medically necessary; however, individuals may desire treatment due to cosmetic concerns or discomfort. Management primarily involves regular application of moisturizers, especially those containing urea, lactic acid, or salicylic acid, which can help to exfoliate and soften the skin. More severe cases may warrant treatment with retinoid creams, which are derivatives of vitamin A that promote cell turnover and prevent the plugging of hair follicles<ref>,

 Keratosis pilaris and its subtypes: associations, new molecular and pharmacologic etiologies, and therapeutic options, 
 ,</ref>.

See Also[edit]

References[edit]

<references />

This article is a medical stub. You can help WikiMD by expanding it!
PubMed
Wikipedia