Curling's ulcer: Difference between revisions
From WikiMD's Medical Encyclopedia
CSV import Tags: mobile edit mobile web edit |
CSV import |
||
| Line 1: | Line 1: | ||
{{Infobox medical condition | |||
| name = Curling's ulcer | |||
| synonyms = Stress ulcer | |||
| field = [[Gastroenterology]] | |||
| symptoms = [[Abdominal pain]], [[nausea]], [[vomiting]], [[hematemesis]] | |||
| complications = [[Gastrointestinal bleeding]], [[perforation (medical)|perforation]] | |||
| onset = Acute, often within 72 hours of severe [[burn]] | |||
| duration = Variable, depending on treatment | |||
| causes = Severe [[burn]]s, [[trauma (medicine)|trauma]], [[sepsis]], [[shock (circulatory)|shock]] | |||
| risks = High [[total body surface area]] burns, prolonged [[intensive care unit|ICU]] stay | |||
| diagnosis = [[Endoscopy]], [[upper gastrointestinal series]] | |||
| differential = [[Peptic ulcer disease]], [[Zollinger-Ellison syndrome]], [[Mallory-Weiss syndrome]] | |||
| prevention = [[Proton pump inhibitor]]s, [[H2 receptor antagonist]]s | |||
| treatment = [[Proton pump inhibitor]]s, [[H2 receptor antagonist]]s, [[antacid]]s, [[surgery]] in severe cases | |||
| prognosis = Good with treatment, but depends on underlying condition | |||
| frequency = Rare, but more common in patients with severe [[burn]]s | |||
}} | |||
'''Curling's ulcer''' is a type of [[peptic ulcer]] that develops in patients with severe burns, trauma, or critical illnesses. It was first described by the British doctor [[Thomas Blizard Curling]] in 1842. | '''Curling's ulcer''' is a type of [[peptic ulcer]] that develops in patients with severe burns, trauma, or critical illnesses. It was first described by the British doctor [[Thomas Blizard Curling]] in 1842. | ||
==Etiology== | ==Etiology== | ||
Curling's ulcer is caused by reduced [[mucosal]] blood flow and increased [[gastric acid]] secretion, which are common in patients with severe burns or trauma. The exact mechanism is not fully understood, but it is believed to involve a combination of [[ischemia]], [[reperfusion injury]], and [[oxidative stress]]. | Curling's ulcer is caused by reduced [[mucosal]] blood flow and increased [[gastric acid]] secretion, which are common in patients with severe burns or trauma. The exact mechanism is not fully understood, but it is believed to involve a combination of [[ischemia]], [[reperfusion injury]], and [[oxidative stress]]. | ||
==Clinical Features== | ==Clinical Features== | ||
Patients with Curling's ulcer may present with [[abdominal pain]], [[nausea]], [[vomiting]], and [[melena]] (black, tarry stools). In severe cases, the ulcer can perforate, leading to [[peritonitis]] and [[septic shock]]. | Patients with Curling's ulcer may present with [[abdominal pain]], [[nausea]], [[vomiting]], and [[melena]] (black, tarry stools). In severe cases, the ulcer can perforate, leading to [[peritonitis]] and [[septic shock]]. | ||
==Diagnosis== | ==Diagnosis== | ||
The diagnosis of Curling's ulcer is usually made by [[endoscopy]], which allows direct visualization of the ulcer. Other diagnostic tests may include a [[complete blood count]] (CBC), [[liver function tests]], and a [[stool test]] for [[occult blood]]. | The diagnosis of Curling's ulcer is usually made by [[endoscopy]], which allows direct visualization of the ulcer. Other diagnostic tests may include a [[complete blood count]] (CBC), [[liver function tests]], and a [[stool test]] for [[occult blood]]. | ||
==Treatment== | ==Treatment== | ||
The treatment of Curling's ulcer involves [[acid suppression]] with [[proton pump inhibitors]] (PPIs) or [[H2 receptor antagonists]], and [[cytoprotective agents]] such as [[sucralfate]]. In severe cases, [[surgery]] may be required to repair a perforated ulcer. | The treatment of Curling's ulcer involves [[acid suppression]] with [[proton pump inhibitors]] (PPIs) or [[H2 receptor antagonists]], and [[cytoprotective agents]] such as [[sucralfate]]. In severe cases, [[surgery]] may be required to repair a perforated ulcer. | ||
==Prevention== | ==Prevention== | ||
Prevention of Curling's ulcer in critically ill patients involves early [[enteral nutrition]], stress ulcer prophylaxis with PPIs or H2 receptor antagonists, and careful monitoring for signs of gastrointestinal bleeding. | Prevention of Curling's ulcer in critically ill patients involves early [[enteral nutrition]], stress ulcer prophylaxis with PPIs or H2 receptor antagonists, and careful monitoring for signs of gastrointestinal bleeding. | ||
==See Also== | ==See Also== | ||
* [[Peptic ulcer]] | * [[Peptic ulcer]] | ||
* [[Stress ulcer]] | * [[Stress ulcer]] | ||
* [[Cushing's ulcer]] | * [[Cushing's ulcer]] | ||
==References== | ==References== | ||
<references /> | <references /> | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Critical care medicine]] | [[Category:Critical care medicine]] | ||
[[Category:Medical conditions]] | [[Category:Medical conditions]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 04:01, 4 April 2025
| Curling's ulcer | |
|---|---|
| Synonyms | Stress ulcer |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Abdominal pain, nausea, vomiting, hematemesis |
| Complications | Gastrointestinal bleeding, perforation |
| Onset | Acute, often within 72 hours of severe burn |
| Duration | Variable, depending on treatment |
| Types | N/A |
| Causes | Severe burns, trauma, sepsis, shock |
| Risks | High total body surface area burns, prolonged ICU stay |
| Diagnosis | Endoscopy, upper gastrointestinal series |
| Differential diagnosis | Peptic ulcer disease, Zollinger-Ellison syndrome, Mallory-Weiss syndrome |
| Prevention | Proton pump inhibitors, H2 receptor antagonists |
| Treatment | Proton pump inhibitors, H2 receptor antagonists, antacids, surgery in severe cases |
| Medication | N/A |
| Prognosis | Good with treatment, but depends on underlying condition |
| Frequency | Rare, but more common in patients with severe burns |
| Deaths | N/A |
Curling's ulcer is a type of peptic ulcer that develops in patients with severe burns, trauma, or critical illnesses. It was first described by the British doctor Thomas Blizard Curling in 1842.
Etiology[edit]
Curling's ulcer is caused by reduced mucosal blood flow and increased gastric acid secretion, which are common in patients with severe burns or trauma. The exact mechanism is not fully understood, but it is believed to involve a combination of ischemia, reperfusion injury, and oxidative stress.
Clinical Features[edit]
Patients with Curling's ulcer may present with abdominal pain, nausea, vomiting, and melena (black, tarry stools). In severe cases, the ulcer can perforate, leading to peritonitis and septic shock.
Diagnosis[edit]
The diagnosis of Curling's ulcer is usually made by endoscopy, which allows direct visualization of the ulcer. Other diagnostic tests may include a complete blood count (CBC), liver function tests, and a stool test for occult blood.
Treatment[edit]
The treatment of Curling's ulcer involves acid suppression with proton pump inhibitors (PPIs) or H2 receptor antagonists, and cytoprotective agents such as sucralfate. In severe cases, surgery may be required to repair a perforated ulcer.
Prevention[edit]
Prevention of Curling's ulcer in critically ill patients involves early enteral nutrition, stress ulcer prophylaxis with PPIs or H2 receptor antagonists, and careful monitoring for signs of gastrointestinal bleeding.
See Also[edit]
References[edit]
<references />
