Hypergammaglobulinemia: Difference between revisions
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{{Infobox medical condition | |||
| name = Hypergammaglobulinemia | |||
| synonyms = | |||
| specialty = [[Immunology]] | |||
| symptoms = Elevated levels of [[gamma globulins]] in the blood | |||
| complications = [[Autoimmune diseases]], [[infections]] | |||
| onset = Varies depending on underlying cause | |||
| duration = Chronic | |||
| causes = [[Chronic infections]], [[autoimmune disorders]], [[liver disease]], [[monoclonal gammopathy]] | |||
| risks = | |||
| diagnosis = [[Blood test]] showing elevated [[immunoglobulins]] | |||
| differential = [[Monoclonal gammopathy of undetermined significance]], [[multiple myeloma]], [[chronic lymphocytic leukemia]] | |||
| prevention = | |||
| treatment = Address underlying cause, [[immunosuppressive therapy]] | |||
| medication = [[Corticosteroids]], [[immunosuppressants]] | |||
| prognosis = Depends on underlying condition | |||
| frequency = Common in certain populations with chronic conditions | |||
}} | |||
'''Hypergammaglobulinemia''' is a condition characterized by an excess of [[gamma globulins]] in the blood. Gamma globulins are a type of [[protein]] produced by the [[immune system]] to help fight infections. Hypergammaglobulinemia can be a sign of various underlying conditions, including chronic [[infections]], [[autoimmune diseases]], and certain types of [[cancer]]. | '''Hypergammaglobulinemia''' is a condition characterized by an excess of [[gamma globulins]] in the blood. Gamma globulins are a type of [[protein]] produced by the [[immune system]] to help fight infections. Hypergammaglobulinemia can be a sign of various underlying conditions, including chronic [[infections]], [[autoimmune diseases]], and certain types of [[cancer]]. | ||
== Causes == | == Causes == | ||
Hypergammaglobulinemia can be caused by a variety of conditions, including: | Hypergammaglobulinemia can be caused by a variety of conditions, including: | ||
* Chronic infections, such as [[hepatitis]] or [[HIV]] | * Chronic infections, such as [[hepatitis]] or [[HIV]] | ||
* Autoimmune diseases, such as [[rheumatoid arthritis]] or [[systemic lupus erythematosus]] | * Autoimmune diseases, such as [[rheumatoid arthritis]] or [[systemic lupus erythematosus]] | ||
* Certain types of cancer, such as [[multiple myeloma]] or [[lymphoma]] | * Certain types of cancer, such as [[multiple myeloma]] or [[lymphoma]] | ||
== Symptoms == | == Symptoms == | ||
The symptoms of hypergammaglobulinemia can vary depending on the underlying cause. They may include: | The symptoms of hypergammaglobulinemia can vary depending on the underlying cause. They may include: | ||
* Fatigue | * Fatigue | ||
* Joint pain | * Joint pain | ||
* Swollen [[lymph nodes]] | * Swollen [[lymph nodes]] | ||
* Recurrent infections | * Recurrent infections | ||
== Diagnosis == | == Diagnosis == | ||
Hypergammaglobulinemia is typically diagnosed through a [[blood test]] that measures the levels of gamma globulins in the blood. Additional tests may be needed to determine the underlying cause. | Hypergammaglobulinemia is typically diagnosed through a [[blood test]] that measures the levels of gamma globulins in the blood. Additional tests may be needed to determine the underlying cause. | ||
== Treatment == | == Treatment == | ||
Treatment for hypergammaglobulinemia typically involves addressing the underlying cause. This may involve [[antibiotics]] for infections, [[immunosuppressive drugs]] for autoimmune diseases, or [[chemotherapy]] for cancer. | Treatment for hypergammaglobulinemia typically involves addressing the underlying cause. This may involve [[antibiotics]] for infections, [[immunosuppressive drugs]] for autoimmune diseases, or [[chemotherapy]] for cancer. | ||
== See also == | == See also == | ||
* [[Gamma globulin]] | * [[Gamma globulin]] | ||
* [[Immunoglobulin]] | * [[Immunoglobulin]] | ||
* [[Multiple myeloma]] | * [[Multiple myeloma]] | ||
* [[Lymphoma]] | * [[Lymphoma]] | ||
[[Category:Medical conditions]] | [[Category:Medical conditions]] | ||
[[Category:Immunology]] | [[Category:Immunology]] | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
{{stub}} | {{stub}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 02:14, 4 April 2025
| Hypergammaglobulinemia | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | Immunology |
| Symptoms | Elevated levels of gamma globulins in the blood |
| Complications | Autoimmune diseases, infections |
| Onset | Varies depending on underlying cause |
| Duration | Chronic |
| Types | N/A |
| Causes | Chronic infections, autoimmune disorders, liver disease, monoclonal gammopathy |
| Risks | |
| Diagnosis | Blood test showing elevated immunoglobulins |
| Differential diagnosis | Monoclonal gammopathy of undetermined significance, multiple myeloma, chronic lymphocytic leukemia |
| Prevention | |
| Treatment | Address underlying cause, immunosuppressive therapy |
| Medication | Corticosteroids, immunosuppressants |
| Prognosis | Depends on underlying condition |
| Frequency | Common in certain populations with chronic conditions |
| Deaths | N/A |
Hypergammaglobulinemia is a condition characterized by an excess of gamma globulins in the blood. Gamma globulins are a type of protein produced by the immune system to help fight infections. Hypergammaglobulinemia can be a sign of various underlying conditions, including chronic infections, autoimmune diseases, and certain types of cancer.
Causes[edit]
Hypergammaglobulinemia can be caused by a variety of conditions, including:
- Chronic infections, such as hepatitis or HIV
- Autoimmune diseases, such as rheumatoid arthritis or systemic lupus erythematosus
- Certain types of cancer, such as multiple myeloma or lymphoma
Symptoms[edit]
The symptoms of hypergammaglobulinemia can vary depending on the underlying cause. They may include:
- Fatigue
- Joint pain
- Swollen lymph nodes
- Recurrent infections
Diagnosis[edit]
Hypergammaglobulinemia is typically diagnosed through a blood test that measures the levels of gamma globulins in the blood. Additional tests may be needed to determine the underlying cause.
Treatment[edit]
Treatment for hypergammaglobulinemia typically involves addressing the underlying cause. This may involve antibiotics for infections, immunosuppressive drugs for autoimmune diseases, or chemotherapy for cancer.
