Thermal trauma: Difference between revisions
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{{Infobox medical condition | |||
| name = Thermal trauma | |||
| synonyms = [[Burn injury]], [[heat injury]] | |||
| field = [[Emergency medicine]], [[Traumatology]] | |||
| symptoms = [[Pain]], [[redness]], [[swelling]], [[blisters]], [[charring]] | |||
| complications = [[Infection]], [[hypovolemia]], [[hypothermia]], [[scarring]], [[contractures]] | |||
| onset = Immediate | |||
| duration = Varies depending on severity | |||
| causes = [[Heat]], [[flame]], [[scald]], [[radiation]], [[chemical]], [[electrical]] | |||
| risks = [[Fire hazards]], [[hot liquids]], [[chemicals]], [[electricity]] | |||
| diagnosis = [[Clinical assessment]], [[burn depth evaluation]] | |||
| differential = [[Frostbite]], [[chemical burns]], [[radiation burns]] | |||
| prevention = [[Fire safety]], [[protective clothing]], [[safe handling of chemicals]] | |||
| treatment = [[Cooling]], [[fluid resuscitation]], [[pain management]], [[wound care]], [[surgery]] | |||
| prognosis = Depends on [[burn severity]] and [[treatment]] | |||
| frequency = Common | |||
}} | |||
'''TFM-4AS-1''' is a [[synthetic]] [[estrogen]] that is used in scientific research. It is part of a group of compounds known as [[SERMs]] or selective estrogen receptor modulators. TFM-4AS-1 is known for its high [[affinity]] for the estrogen receptor and its selective action in different tissues. | '''TFM-4AS-1''' is a [[synthetic]] [[estrogen]] that is used in scientific research. It is part of a group of compounds known as [[SERMs]] or selective estrogen receptor modulators. TFM-4AS-1 is known for its high [[affinity]] for the estrogen receptor and its selective action in different tissues. | ||
== History == | == History == | ||
TFM-4AS-1 was first synthesized in the late 20th century as part of a series of compounds designed to investigate the actions of estrogens in the body. It has since been used in a variety of research settings to study the effects of estrogens on different tissues. | TFM-4AS-1 was first synthesized in the late 20th century as part of a series of compounds designed to investigate the actions of estrogens in the body. It has since been used in a variety of research settings to study the effects of estrogens on different tissues. | ||
== Mechanism of Action == | == Mechanism of Action == | ||
TFM-4AS-1 acts by binding to the estrogen receptor, a protein found in many different tissues in the body. Once bound, it can either activate or inhibit the receptor, depending on the specific tissue. This selective action is what gives TFM-4AS-1 its classification as a SERM. | TFM-4AS-1 acts by binding to the estrogen receptor, a protein found in many different tissues in the body. Once bound, it can either activate or inhibit the receptor, depending on the specific tissue. This selective action is what gives TFM-4AS-1 its classification as a SERM. | ||
== Uses in Research == | == Uses in Research == | ||
In research settings, TFM-4AS-1 is often used to study the effects of estrogens on different tissues. For example, it can be used to investigate the role of estrogens in bone health, cardiovascular health, and the development of certain cancers. | In research settings, TFM-4AS-1 is often used to study the effects of estrogens on different tissues. For example, it can be used to investigate the role of estrogens in bone health, cardiovascular health, and the development of certain cancers. | ||
== Side Effects == | == Side Effects == | ||
As a research compound, TFM-4AS-1 is not typically used in humans, so its side effects are not well known. However, like all SERMs, it has the potential to cause side effects related to its estrogenic and anti-estrogenic actions. | As a research compound, TFM-4AS-1 is not typically used in humans, so its side effects are not well known. However, like all SERMs, it has the potential to cause side effects related to its estrogenic and anti-estrogenic actions. | ||
== See Also == | == See Also == | ||
* [[Selective estrogen receptor modulator]] | * [[Selective estrogen receptor modulator]] | ||
* [[Estrogen receptor]] | * [[Estrogen receptor]] | ||
* [[Synthetic estrogen]] | * [[Synthetic estrogen]] | ||
[[Category:SERMs]] | [[Category:SERMs]] | ||
[[Category:Synthetic estrogens]] | [[Category:Synthetic estrogens]] | ||
[[Category:Research compounds]] | [[Category:Research compounds]] | ||
{{stub}} | {{stub}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 23:46, 3 April 2025
| Thermal trauma | |
|---|---|
| Synonyms | Burn injury, heat injury |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Pain, redness, swelling, blisters, charring |
| Complications | Infection, hypovolemia, hypothermia, scarring, contractures |
| Onset | Immediate |
| Duration | Varies depending on severity |
| Types | N/A |
| Causes | Heat, flame, scald, radiation, chemical, electrical |
| Risks | Fire hazards, hot liquids, chemicals, electricity |
| Diagnosis | Clinical assessment, burn depth evaluation |
| Differential diagnosis | Frostbite, chemical burns, radiation burns |
| Prevention | Fire safety, protective clothing, safe handling of chemicals |
| Treatment | Cooling, fluid resuscitation, pain management, wound care, surgery |
| Medication | N/A |
| Prognosis | Depends on burn severity and treatment |
| Frequency | Common |
| Deaths | N/A |
TFM-4AS-1 is a synthetic estrogen that is used in scientific research. It is part of a group of compounds known as SERMs or selective estrogen receptor modulators. TFM-4AS-1 is known for its high affinity for the estrogen receptor and its selective action in different tissues.
History[edit]
TFM-4AS-1 was first synthesized in the late 20th century as part of a series of compounds designed to investigate the actions of estrogens in the body. It has since been used in a variety of research settings to study the effects of estrogens on different tissues.
Mechanism of Action[edit]
TFM-4AS-1 acts by binding to the estrogen receptor, a protein found in many different tissues in the body. Once bound, it can either activate or inhibit the receptor, depending on the specific tissue. This selective action is what gives TFM-4AS-1 its classification as a SERM.
Uses in Research[edit]
In research settings, TFM-4AS-1 is often used to study the effects of estrogens on different tissues. For example, it can be used to investigate the role of estrogens in bone health, cardiovascular health, and the development of certain cancers.
Side Effects[edit]
As a research compound, TFM-4AS-1 is not typically used in humans, so its side effects are not well known. However, like all SERMs, it has the potential to cause side effects related to its estrogenic and anti-estrogenic actions.
