Parkinson-plus syndrome: Difference between revisions
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{{Infobox medical condition | |||
| name = Parkinson-plus syndrome | |||
| synonyms = [[Atypical parkinsonism]] | |||
| field = [[Neurology]] | |||
| symptoms = [[Tremor]], [[rigidity (medicine)|rigidity]], [[bradykinesia]], [[postural instability]], additional neurological symptoms | |||
| onset = Typically after age 50 | |||
| duration = Progressive | |||
| types = [[Multiple system atrophy]], [[Progressive supranuclear palsy]], [[Corticobasal degeneration]], [[Dementia with Lewy bodies]] | |||
| causes = Unknown, possibly [[genetic]] and [[environmental factors]] | |||
| risks = Age, family history | |||
| diagnosis = Clinical evaluation, [[MRI]], [[PET scan]] | |||
| differential = [[Parkinson's disease]], [[Essential tremor]], [[Normal pressure hydrocephalus]] | |||
| treatment = [[Levodopa]], [[dopamine agonists]], [[physical therapy]], [[occupational therapy]] | |||
| prognosis = Variable, generally poorer than [[Parkinson's disease]] | |||
| frequency = Rare compared to [[Parkinson's disease]] | |||
}} | |||
'''Parkinson-plus syndrome''' is a group of neurological disorders that share features with [[Parkinson's disease]], but have additional symptoms and a more rapid progression. These disorders include [[Multiple system atrophy]] (MSA), [[Progressive supranuclear palsy]] (PSP), [[Corticobasal degeneration]] (CBD), and [[Dementia with Lewy bodies]] (DLB). | '''Parkinson-plus syndrome''' is a group of neurological disorders that share features with [[Parkinson's disease]], but have additional symptoms and a more rapid progression. These disorders include [[Multiple system atrophy]] (MSA), [[Progressive supranuclear palsy]] (PSP), [[Corticobasal degeneration]] (CBD), and [[Dementia with Lewy bodies]] (DLB). | ||
== Symptoms == | == Symptoms == | ||
The symptoms of Parkinson-plus syndromes are similar to those of Parkinson's disease, including [[bradykinesia]] (slowness of movement), [[rigidity]] (stiffness), and [[tremor]]. However, these disorders also have additional symptoms that are not typically seen in Parkinson's disease. These can include problems with balance and coordination, difficulty swallowing, changes in speech, and cognitive impairment. | The symptoms of Parkinson-plus syndromes are similar to those of Parkinson's disease, including [[bradykinesia]] (slowness of movement), [[rigidity]] (stiffness), and [[tremor]]. However, these disorders also have additional symptoms that are not typically seen in Parkinson's disease. These can include problems with balance and coordination, difficulty swallowing, changes in speech, and cognitive impairment. | ||
== Causes == | == Causes == | ||
The exact cause of Parkinson-plus syndromes is unknown, but they are thought to be related to the accumulation of abnormal proteins in the brain. These proteins can damage nerve cells and lead to the symptoms of the disease. | The exact cause of Parkinson-plus syndromes is unknown, but they are thought to be related to the accumulation of abnormal proteins in the brain. These proteins can damage nerve cells and lead to the symptoms of the disease. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of Parkinson-plus syndromes can be challenging, as the symptoms can be similar to those of other neurological disorders. Doctors may use a combination of medical history, physical examination, and imaging tests to make a diagnosis. | Diagnosis of Parkinson-plus syndromes can be challenging, as the symptoms can be similar to those of other neurological disorders. Doctors may use a combination of medical history, physical examination, and imaging tests to make a diagnosis. | ||
== Treatment == | == Treatment == | ||
There is currently no cure for Parkinson-plus syndromes, but treatments can help manage symptoms. These may include medications, physical therapy, and in some cases, surgery. | There is currently no cure for Parkinson-plus syndromes, but treatments can help manage symptoms. These may include medications, physical therapy, and in some cases, surgery. | ||
== See also == | == See also == | ||
* [[Parkinson's disease]] | * [[Parkinson's disease]] | ||
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* [[Corticobasal degeneration]] | * [[Corticobasal degeneration]] | ||
* [[Dementia with Lewy bodies]] | * [[Dementia with Lewy bodies]] | ||
[[Category:Neurological disorders]] | [[Category:Neurological disorders]] | ||
[[Category:Parkinson's disease]] | [[Category:Parkinson's disease]] | ||
[[Category:Syndromes]] | [[Category:Syndromes]] | ||
{{stub}} | {{stub}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 23:12, 3 April 2025
| Parkinson-plus syndrome | |
|---|---|
| Synonyms | Atypical parkinsonism |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Tremor, rigidity, bradykinesia, postural instability, additional neurological symptoms |
| Complications | N/A |
| Onset | Typically after age 50 |
| Duration | Progressive |
| Types | Multiple system atrophy, Progressive supranuclear palsy, Corticobasal degeneration, Dementia with Lewy bodies |
| Causes | Unknown, possibly genetic and environmental factors |
| Risks | Age, family history |
| Diagnosis | Clinical evaluation, MRI, PET scan |
| Differential diagnosis | Parkinson's disease, Essential tremor, Normal pressure hydrocephalus |
| Prevention | N/A |
| Treatment | Levodopa, dopamine agonists, physical therapy, occupational therapy |
| Medication | N/A |
| Prognosis | Variable, generally poorer than Parkinson's disease |
| Frequency | Rare compared to Parkinson's disease |
| Deaths | N/A |
Parkinson-plus syndrome is a group of neurological disorders that share features with Parkinson's disease, but have additional symptoms and a more rapid progression. These disorders include Multiple system atrophy (MSA), Progressive supranuclear palsy (PSP), Corticobasal degeneration (CBD), and Dementia with Lewy bodies (DLB).
Symptoms[edit]
The symptoms of Parkinson-plus syndromes are similar to those of Parkinson's disease, including bradykinesia (slowness of movement), rigidity (stiffness), and tremor. However, these disorders also have additional symptoms that are not typically seen in Parkinson's disease. These can include problems with balance and coordination, difficulty swallowing, changes in speech, and cognitive impairment.
Causes[edit]
The exact cause of Parkinson-plus syndromes is unknown, but they are thought to be related to the accumulation of abnormal proteins in the brain. These proteins can damage nerve cells and lead to the symptoms of the disease.
Diagnosis[edit]
Diagnosis of Parkinson-plus syndromes can be challenging, as the symptoms can be similar to those of other neurological disorders. Doctors may use a combination of medical history, physical examination, and imaging tests to make a diagnosis.
Treatment[edit]
There is currently no cure for Parkinson-plus syndromes, but treatments can help manage symptoms. These may include medications, physical therapy, and in some cases, surgery.
