Corticobasal degeneration

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Corticobasal Degeneration (kor-ti-ko-ba-sal de-gen-er-a-tion) is a rare, progressive neurodegenerative disease that affects the cortex and basal ganglia of the brain.

Etymology

The term "Corticobasal Degeneration" is derived from the areas of the brain that are primarily affected by the disease: the cerebral cortex and the basal ganglia. "Degeneration" refers to the progressive deterioration of these areas.

Definition

Corticobasal Degeneration (CBD) is a type of Parkinsonism characterized by a combination of motor, cognitive, and behavioral symptoms. It is caused by the degeneration of multiple areas of the brain, including the frontal and parietal lobes and the basal ganglia. The disease is often associated with abnormal protein deposits known as tau proteins.

Symptoms

The symptoms of Corticobasal Degeneration can vary widely among individuals but often include:

Diagnosis

Diagnosis of Corticobasal Degeneration is primarily based on clinical examination and the presence of characteristic symptoms. Neuroimaging techniques such as MRI and PET scan can be used to support the diagnosis. However, definitive diagnosis can only be confirmed through post-mortem examination of the brain.

Treatment

There is currently no cure for Corticobasal Degeneration. Treatment is symptomatic and may include medications to manage motor symptoms, physical and occupational therapy, and speech therapy for language difficulties.

Prognosis

Corticobasal Degeneration is a progressive disease, with symptoms typically worsening over time. The rate of progression can vary widely among individuals.

See Also

External links

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