Methandriol: Difference between revisions

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'''Methandriol''' is an [[anabolic steroid]] that is used in [[medicine]] to treat a variety of conditions. It is also known by its chemical name, 17α-methylandrostenediol.
{{Short description|An anabolic steroid}}
{{Drugbox
| verifiedfields = changed
| verifiedrevid = 477002295
| IUPAC_name = 17α-Methylandrost-5-ene-3β,17β-diol
| image = Methandriol.svg
| image_size = 200px
| image_alt = Structural formula of Methandriol
| width =
| alt =
| CAS_number = 521-10-8
| ATC_prefix =
| ATC_suffix =
| PubChem = 3032564
| DrugBank = DB01436
| ChemSpiderID = 2290000
| UNII = 1JQS135EYN
| KEGG = D05032
| ChEBI = 34858
| ChEMBL = 2104524
| C=20
| H=32
| O=2
| smiles = CC(C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](CC[C@]4(C)[C@@H]3CC[C@]12C)O
| StdInChI = 1S/C20H32O2/c1-13(2)14-5-6-15-16-7-8-18-17(16)9-10-20(3)19(18)11-12-21,22/h7-8,13-14,16-17,19-22H,5-6,9-12H2,1-4H3/t16-,17-,19+,20+/m1/s1
| StdInChIKey = YAPQBXQYLJRXSA-CQKQYVBDSA-N
}}


== History ==
'''Methandriol''' is a synthetic [[anabolic steroid]] and a derivative of [[testosterone]]. It is known for its ability to promote muscle growth and enhance physical performance. Methandriol is used in veterinary medicine and has been marketed under various brand names.


Methandriol was first described in the scientific literature in the 1930s. It was developed as a therapeutic agent by the pharmaceutical company [[Organon]]. The drug was initially used to treat conditions such as [[osteoporosis]], [[breast cancer]], and [[delayed puberty]].
==Chemical Structure and Properties==
[[File:Methandriol.svg|thumb|right|Structural formula of Methandriol]]
Methandriol is chemically known as 17α-Methylandrost-5-ene-3β,17β-diol. It is a [[17α-alkylated]] derivative of [[androstenediol]], which is a naturally occurring [[androgen]]. The presence of the 17α-methyl group in methandriol increases its oral bioavailability, allowing it to be administered orally.


== Medical uses ==
==Pharmacology==
Methandriol exhibits both [[anabolic]] and [[androgenic]] properties. It binds to [[androgen receptors]] in muscle tissue, promoting protein synthesis and muscle growth. The anabolic effects of methandriol are utilized in veterinary medicine to improve weight gain and muscle mass in livestock.


Methandriol is used in medicine for its anabolic effects, which include the promotion of muscle growth and the stimulation of appetite. It is also used to treat conditions such as [[osteoporosis]], [[breast cancer]], and [[delayed puberty]]. In addition, methandriol has been used to treat [[endometriosis]], a condition in which tissue similar to the lining of the uterus grows outside of the uterus.
==Medical Uses==
Methandriol is primarily used in veterinary medicine. It has been used to promote growth in animals such as cattle and sheep. In humans, methandriol has been used in the past for its anabolic effects, but its use is limited due to the availability of other anabolic steroids with more favorable safety profiles.


== Side effects ==
==Side Effects==
The use of methandriol can lead to several side effects, particularly when used in high doses or for extended periods. Common side effects include [[liver toxicity]], [[hypertension]], and [[acne]]. Due to its androgenic properties, methandriol can also cause [[virilization]] in women, leading to the development of male characteristics.


Like other anabolic steroids, methandriol can have a number of side effects. These can include [[acne]], [[hair loss]], and [[gynecomastia]] (the development of breast tissue in men). In addition, methandriol can have more serious side effects, such as [[liver damage]] and [[cardiovascular disease]].
==Legal Status==
 
Methandriol is classified as a controlled substance in many countries due to its potential for abuse and adverse health effects. Its use is restricted to veterinary applications in most jurisdictions.
== Legal status ==
 
In many countries, including the United States, methandriol is classified as a [[controlled substance]]. This means that it is illegal to possess, use, or distribute the drug without a prescription.
 
== See also ==


==Related Pages==
* [[Anabolic steroid]]
* [[Anabolic steroid]]
* [[Controlled substance]]
* [[Androgen]]
* [[Endometriosis]]
* [[Testosterone]]
* [[Osteoporosis]]
* [[Androstenediol]]


[[Category:Anabolic steroids]]
[[Category:Anabolic steroids]]
[[Category:Controlled substances]]
[[Category:Androgens and anabolic steroids]]
[[Category:Endometriosis]]
[[Category:Veterinary drugs]]
[[Category:Osteoporosis]]
{{anabolic steroid}}
{{controlled substance}}
{{endometriosis}}
{{osteoporosis}}
{{medicine-stub}}
<gallery>
File:Methandriol.svg|Methandriol
</gallery>
<gallery>
File:Methandriol.svg|Methandriol
</gallery>

Latest revision as of 11:20, 23 March 2025

An anabolic steroid


Methandriol
INN
Drug class
Routes of administration
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status
CAS Number 521-10-8
PubChem 3032564
DrugBank DB01436
ChemSpider 2290000
KEGG D05032


Methandriol is a synthetic anabolic steroid and a derivative of testosterone. It is known for its ability to promote muscle growth and enhance physical performance. Methandriol is used in veterinary medicine and has been marketed under various brand names.

Chemical Structure and Properties[edit]

Structural formula of Methandriol

Methandriol is chemically known as 17α-Methylandrost-5-ene-3β,17β-diol. It is a 17α-alkylated derivative of androstenediol, which is a naturally occurring androgen. The presence of the 17α-methyl group in methandriol increases its oral bioavailability, allowing it to be administered orally.

Pharmacology[edit]

Methandriol exhibits both anabolic and androgenic properties. It binds to androgen receptors in muscle tissue, promoting protein synthesis and muscle growth. The anabolic effects of methandriol are utilized in veterinary medicine to improve weight gain and muscle mass in livestock.

Medical Uses[edit]

Methandriol is primarily used in veterinary medicine. It has been used to promote growth in animals such as cattle and sheep. In humans, methandriol has been used in the past for its anabolic effects, but its use is limited due to the availability of other anabolic steroids with more favorable safety profiles.

Side Effects[edit]

The use of methandriol can lead to several side effects, particularly when used in high doses or for extended periods. Common side effects include liver toxicity, hypertension, and acne. Due to its androgenic properties, methandriol can also cause virilization in women, leading to the development of male characteristics.

Legal Status[edit]

Methandriol is classified as a controlled substance in many countries due to its potential for abuse and adverse health effects. Its use is restricted to veterinary applications in most jurisdictions.

Related Pages[edit]