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Latest revision as of 12:59, 18 March 2025
MAP or Mitogen-Activated Protein kinases are a type of protein kinase that are specific to the amino acids serine and threonine. They are involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. They regulate cell functions including proliferation, gene expression, differentiation, mitosis, cell survival, and apoptosis.
Function[edit]
MAP kinases are involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. They regulate cell functions including proliferation, gene expression, differentiation, mitosis, cell survival, and apoptosis.
Types[edit]
There are several types of MAP kinases, including ERK, JNK, and p38. Each of these is involved in a specific cellular response.
ERK[edit]
ERK or Extracellular signal–regulated kinases are a type of MAP kinase that is involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.
JNK[edit]
JNK or c-Jun N-terminal kinases are a type of MAP kinase that is involved in the regulation of apoptosis and inflammatory responses.
p38[edit]
p38 MAP kinases are a type of MAP kinase that is involved in the regulation of cellular responses to cytokines and stress.
