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'''Iron''' is a chemical element with the symbol '''Fe''' (from Latin: ferrum) and atomic number 26. It is a metal in the first transition series and plays an essential role in various physiological processes. As a vital mineral, iron contributes significantly to the synthesis of several critical biological substances like [[hemoglobin]], [[myoglobin]], and specific [[enzymes]].
{{Short description|Overview of iron in human health}}
{{Use dmy dates|date=October 2023}}


=== Characteristics ===
==Iron in Human Health==
[[File:Iron supplement.jpg|thumb|right|Iron supplements are commonly used to treat iron deficiency.]]
Iron is a vital mineral that plays a crucial role in various bodily functions. It is an essential component of [[hemoglobin]], the protein in [[red blood cells]] responsible for transporting [[oxygen]] from the lungs to the rest of the body. Iron is also a part of [[myoglobin]], a protein that provides oxygen to muscles, and is involved in numerous [[enzymatic reactions]] that are critical for [[metabolism]].


Iron is:
==Functions of Iron==
* Lustrous, metallic, and malleable.
Iron is indispensable for several physiological processes:
* The fourth most common element in the Earth's crust.
* Prone to corrosion, especially when exposed to moisture or an oxidizing environment.


=== Biological Importance ===
* '''Oxygen Transport''': As a component of hemoglobin, iron facilitates the transport of oxygen in the blood. Each hemoglobin molecule can bind four oxygen molecules, allowing efficient oxygen delivery to tissues.


==== Hemoglobin ====
* '''Energy Production''': Iron is a cofactor for enzymes involved in the [[electron transport chain]], a series of reactions that generate [[adenosine triphosphate]] (ATP), the energy currency of the cell.
* [[Hemoglobin]] is a protein in red blood cells responsible for transporting oxygen from the lungs to the body's tissues.
* Iron forms the core of the heme group in hemoglobin, allowing it to bind with oxygen molecules.  


==== Myoglobin ====
* '''DNA Synthesis''': Iron is necessary for the synthesis of [[deoxyribonucleic acid]] (DNA), the genetic material in cells, which is crucial for cell division and growth.
* [[Myoglobin]], found primarily in muscles, functions as an oxygen storage unit, providing oxygen to muscles during intense physical activity.
* Like hemoglobin, myoglobin contains iron in its heme group, essential for its oxygen-binding capability.


==== Enzymes ====
* '''Immune Function''': Iron plays a role in the proliferation and maturation of [[immune cells]], particularly [[lymphocytes]], which are essential for a robust immune response.
* Many enzymes in the body require iron as a cofactor for their proper function.
* Iron-containing enzymes play critical roles in DNA synthesis, energy production, and protection against harmful free radicals.


=== Dietary Sources ===
==Dietary Sources of Iron==
[[File:Spinach.jpg|thumb|left|Spinach is a plant-based source of iron.]]
Iron is available in two forms in the diet: heme and non-heme iron. Heme iron, found in [[animal products]] such as [[red meat]], [[poultry]], and [[fish]], is more readily absorbed by the body. Non-heme iron, found in [[plant-based foods]] like [[lentils]], [[beans]], [[tofu]], and [[spinach]], is less efficiently absorbed.


Iron is available in a variety of dietary sources. They can be categorized into two main types:
To enhance the absorption of non-heme iron, it is beneficial to consume it with [[vitamin C]]-rich foods, such as [[citrus fruits]], [[bell peppers]], and [[broccoli]].


* '''Heme iron''': Found in animal-based foods like meat, poultry, and fish. It is more efficiently absorbed by the body.
==Iron Deficiency==
* '''Non-heme iron''': Present in plant-based foods such as beans, lentils, spinach, and fortified cereals.
Iron deficiency is the most common nutritional deficiency worldwide and can lead to [[iron deficiency anemia]]. Symptoms of iron deficiency include fatigue, weakness, pale skin, shortness of breath, and dizziness. It is particularly prevalent among [[pregnant women]], [[infants]], and [[adolescents]] due to increased iron requirements.


=== Deficiency and Overload ===
==Iron Overload==
Excessive iron accumulation in the body can lead to a condition known as [[hemochromatosis]]. This can cause damage to organs such as the [[liver]], [[heart]], and [[pancreas]]. Symptoms may include joint pain, fatigue, and skin discoloration. Management involves regular [[phlebotomy]] to remove excess iron from the body.


* '''[[Iron-deficiency anemia]]''': The most common nutritional deficiency worldwide. Symptoms include fatigue, weakness, and pallor. It can result from inadequate iron intake, poor absorption, or excessive blood loss.
==Iron Supplementation==
* '''[[Iron overload]]''': Excessive iron levels can be harmful. Hereditary hemochromatosis is a genetic disorder that causes iron to accumulate in the body, leading to organ damage.
Iron supplements are often prescribed to individuals with iron deficiency anemia. These supplements come in various forms, including ferrous sulfate, ferrous gluconate, and ferrous fumarate. It is important to take iron supplements under medical supervision to avoid potential side effects and complications.


=== Industrial and Other Uses ===
==Related Pages==
* [[Anemia]]
* [[Hemoglobin]]
* [[Nutrition]]
* [[Metabolism]]


Outside of its biological significance, iron is also:
[[Category:Minerals]]
* Used in the production of steel, which is a primary material in construction and manufacturing.
* Employed in producing pigments, cosmetics, and inks.
* Integral in the creation of magnets due to its ferromagnetic properties.
 
== Conclusion ==
 
Iron, both as an element and a vital mineral, has immense importance in the functioning of living organisms and various industrial applications. The dual role it plays, from ensuring oxygen transport in our bodies to building skyscrapers, underscores its significance in the modern world.
[[Category:Chemical Elements]]
[[Category:Nutrition]]
[[Category:Nutrition]]
[[Category:Metallurgy]]
[[Category:Hematology]]
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File:Iron-alpha-pV.svg|Iron
File:Pure_iron_phase_diagram_(EN).svg|Iron
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File:Outcropping_banded_iron_formation_-_panoramio.jpg|Iron
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File:Iron(III)-oxide-sample.jpg|Iron
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File:Pourbaix_Diagram_of_Iron.svg|Iron
File:Iron(III)_chloride_hexahydrate.jpg|Iron
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Revision as of 17:33, 18 February 2025

Overview of iron in human health



Iron in Human Health

File:Iron supplement.jpg
Iron supplements are commonly used to treat iron deficiency.

Iron is a vital mineral that plays a crucial role in various bodily functions. It is an essential component of hemoglobin, the protein in red blood cells responsible for transporting oxygen from the lungs to the rest of the body. Iron is also a part of myoglobin, a protein that provides oxygen to muscles, and is involved in numerous enzymatic reactions that are critical for metabolism.

Functions of Iron

Iron is indispensable for several physiological processes:

  • Oxygen Transport: As a component of hemoglobin, iron facilitates the transport of oxygen in the blood. Each hemoglobin molecule can bind four oxygen molecules, allowing efficient oxygen delivery to tissues.
  • DNA Synthesis: Iron is necessary for the synthesis of deoxyribonucleic acid (DNA), the genetic material in cells, which is crucial for cell division and growth.
  • Immune Function: Iron plays a role in the proliferation and maturation of immune cells, particularly lymphocytes, which are essential for a robust immune response.

Dietary Sources of Iron

Spinach is a plant-based source of iron.

Iron is available in two forms in the diet: heme and non-heme iron. Heme iron, found in animal products such as red meat, poultry, and fish, is more readily absorbed by the body. Non-heme iron, found in plant-based foods like lentils, beans, tofu, and spinach, is less efficiently absorbed.

To enhance the absorption of non-heme iron, it is beneficial to consume it with vitamin C-rich foods, such as citrus fruits, bell peppers, and broccoli.

Iron Deficiency

Iron deficiency is the most common nutritional deficiency worldwide and can lead to iron deficiency anemia. Symptoms of iron deficiency include fatigue, weakness, pale skin, shortness of breath, and dizziness. It is particularly prevalent among pregnant women, infants, and adolescents due to increased iron requirements.

Iron Overload

Excessive iron accumulation in the body can lead to a condition known as hemochromatosis. This can cause damage to organs such as the liver, heart, and pancreas. Symptoms may include joint pain, fatigue, and skin discoloration. Management involves regular phlebotomy to remove excess iron from the body.

Iron Supplementation

Iron supplements are often prescribed to individuals with iron deficiency anemia. These supplements come in various forms, including ferrous sulfate, ferrous gluconate, and ferrous fumarate. It is important to take iron supplements under medical supervision to avoid potential side effects and complications.

Related Pages