Ciprefadol: Difference between revisions

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'''Ciprefadol''' is a [[synthetic opioid]] that was developed in the late 1970s. It is a [[narcotic analgesic]] that is primarily used in the treatment of moderate to severe pain. Ciprefadol is a member of the 4-phenylpiperidine class of opioids and is closely related to the highly potent opioid analgesic, [[fentanyl]].
{{Short description|An overview of the analgesic drug Ciprefadol}}
{{Drugbox
| verifiedfields = changed
| verifiedrevid = 477002123
| image = Ciprefadol_Structure.svg
| image_size = 200px
| image_alt = Chemical structure of Ciprefadol
}}
 
'''Ciprefadol''' is a synthetic opioid analgesic that has been studied for its potential use in pain management. It is part of a class of drugs known as [[opioid]]s, which are substances that act on [[opioid receptor]]s to produce morphine-like effects. Opioids are primarily used for pain relief, including [[anesthesia]].
 
==Chemical Structure==
[[File:Ciprefadol_Structure.svg|thumb|right|200px|Chemical structure of Ciprefadol]]
Ciprefadol has a unique chemical structure that distinguishes it from other opioids. The structure of Ciprefadol includes a complex arrangement of carbon, hydrogen, and nitrogen atoms, which contribute to its pharmacological properties. The presence of specific functional groups in its structure is responsible for its interaction with opioid receptors.


==Pharmacology==
==Pharmacology==
Ciprefadol acts as a [[mu-opioid receptor]] agonist. It has a high affinity for the mu-opioid receptor, which is the primary site of action for most opioid drugs. The activation of these receptors in the brain and spinal cord reduces the perception of pain.
Ciprefadol acts primarily as an agonist at the [[mu-opioid receptor]], which is the same receptor targeted by other well-known opioids such as [[morphine]] and [[fentanyl]]. Activation of these receptors leads to analgesic effects, making Ciprefadol a potential candidate for pain management. However, like other opioids, it may also produce side effects such as [[respiratory depression]], [[constipation]], and potential for [[addiction]].
 
==Chemistry==
Ciprefadol is a synthetic opioid and is part of the 4-phenylpiperidine class of opioids. It is structurally similar to other opioids in this class, such as fentanyl and [[sufentanil]]. The chemical structure of ciprefadol includes a phenyl ring attached to a piperidine ring, which is a common feature of this class of drugs.


==Clinical Use==
==Clinical Use==
Ciprefadol is used in the treatment of moderate to severe pain. It is often used in situations where other pain medications are not effective. Due to its potency, it is typically reserved for use in patients with severe chronic pain or in those who have developed a tolerance to other opioids.
While Ciprefadol has shown promise in preclinical studies, its clinical use is not well established. Research is ongoing to determine its efficacy and safety profile compared to other opioids. The development of new analgesics like Ciprefadol is crucial in the context of the [[opioid crisis]], as there is a need for effective pain management options with reduced risk of addiction and overdose.


==Side Effects==
==Side Effects==
Like all opioids, ciprefadol has a number of potential side effects. These can include [[nausea]], [[vomiting]], [[constipation]], and [[respiratory depression]]. In addition, long-term use of ciprefadol can lead to physical dependence and addiction.
The side effects of Ciprefadol are similar to those of other opioids. Common side effects include:
* [[Nausea]]
* [[Vomiting]]
* [[Drowsiness]]
* [[Dizziness]]
* [[Constipation]]
 
Serious side effects may include:
* [[Respiratory depression]]
* [[Hypotension]]
* [[Bradycardia]]


==See Also==
==Research and Development==
Research into Ciprefadol is focused on understanding its pharmacokinetics and pharmacodynamics, as well as its potential advantages over existing opioid medications. Studies are also exploring its potential use in combination with other analgesics to enhance pain relief while minimizing side effects.
 
==Related pages==
* [[Opioid]]
* [[Opioid]]
* [[Fentanyl]]
* [[Analgesic]]
* [[Sufentanil]]
* [[Pain management]]
* [[Mu-opioid receptor]]
* [[Mu-opioid receptor]]


[[Category:Opioids]]
[[Category:Opioids]]
[[Category:Analgesics]]
[[Category:Analgesics]]
[[Category:Pharmacology]]
[[Category:Chemistry]]
{{stub}}

Latest revision as of 10:59, 15 February 2025

An overview of the analgesic drug Ciprefadol


Ciprefadol
INN
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Routes of administration
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Metabolism
Elimination half-life
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PubChem
DrugBank
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Ciprefadol is a synthetic opioid analgesic that has been studied for its potential use in pain management. It is part of a class of drugs known as opioids, which are substances that act on opioid receptors to produce morphine-like effects. Opioids are primarily used for pain relief, including anesthesia.

Chemical Structure[edit]

Chemical structure of Ciprefadol

Ciprefadol has a unique chemical structure that distinguishes it from other opioids. The structure of Ciprefadol includes a complex arrangement of carbon, hydrogen, and nitrogen atoms, which contribute to its pharmacological properties. The presence of specific functional groups in its structure is responsible for its interaction with opioid receptors.

Pharmacology[edit]

Ciprefadol acts primarily as an agonist at the mu-opioid receptor, which is the same receptor targeted by other well-known opioids such as morphine and fentanyl. Activation of these receptors leads to analgesic effects, making Ciprefadol a potential candidate for pain management. However, like other opioids, it may also produce side effects such as respiratory depression, constipation, and potential for addiction.

Clinical Use[edit]

While Ciprefadol has shown promise in preclinical studies, its clinical use is not well established. Research is ongoing to determine its efficacy and safety profile compared to other opioids. The development of new analgesics like Ciprefadol is crucial in the context of the opioid crisis, as there is a need for effective pain management options with reduced risk of addiction and overdose.

Side Effects[edit]

The side effects of Ciprefadol are similar to those of other opioids. Common side effects include:

Serious side effects may include:

Research and Development[edit]

Research into Ciprefadol is focused on understanding its pharmacokinetics and pharmacodynamics, as well as its potential advantages over existing opioid medications. Studies are also exploring its potential use in combination with other analgesics to enhance pain relief while minimizing side effects.

Related pages[edit]