HOXC10: Difference between revisions

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'''HOXC10''' is a gene that belongs to the [[homeobox]] family of genes. The [[protein]] encoded by this gene is part of the [[Hox]] gene family, which plays a crucial role in [[morphogenesis]] and the development of the body plan.
 
{{Infobox gene
| name = HOXC10
| symbol = HOXC10
| HGNCid = 5115
| chromosome = 12
| arm = q
| band = 13.13
}}
 
'''HOXC10''' is a [[gene]] that encodes a [[homeobox]] [[protein]] involved in the regulation of [[developmental processes]]. It is part of the [[HOX gene]] family, which plays a crucial role in [[embryonic development]] and the [[anterior-posterior axis]] formation.


== Function ==
== Function ==
The HOXC10 gene is involved in the regulation of [[cell differentiation]] and [[body segmentation]] during [[embryonic development]]. It is expressed in a variety of tissues, including the [[central nervous system]], [[skeletal muscle]], and [[reproductive system]]. The protein encoded by the HOXC10 gene acts as a [[transcription factor]], binding to specific DNA sequences and regulating the expression of other genes.
The HOXC10 gene is a member of the [[homeobox]] family of genes, which are known for their role in regulating patterns of anatomical development ([[morphogenesis]]) in [[animals]], [[fungi]], and [[plants]]. The protein encoded by HOXC10 is a [[transcription factor]] that binds to specific [[DNA]] sequences, thereby controlling the expression of other genes. This gene is particularly important in the development of the [[spinal cord]], [[limbs]], and [[urogenital system]].


== Clinical Significance ==
== Clinical Significance ==
Mutations in the HOXC10 gene have been associated with several medical conditions. For instance, aberrant expression of HOXC10 has been linked to the progression of [[cancer]], particularly in [[breast cancer]] and [[ovarian cancer]]. It has also been implicated in the development of [[endometriosis]], a painful condition in which tissue similar to the lining of the uterus grows outside the uterus.
Mutations or dysregulation of the HOXC10 gene have been associated with various [[developmental disorders]] and [[cancers]]. Studies have shown that abnormal expression of HOXC10 may contribute to the progression of certain types of [[breast cancer]] and [[ovarian cancer]].


== Research ==
== Research ==
Research into the HOXC10 gene is ongoing, with scientists seeking to better understand its role in development and disease. This research could potentially lead to new treatments for conditions associated with HOXC10 mutations.
Research on HOXC10 continues to explore its role in [[oncogenesis]] and its potential as a [[biomarker]] for certain cancers. Understanding the mechanisms by which HOXC10 influences [[cell proliferation]] and [[differentiation]] could lead to new therapeutic targets.
 
[[File:HOXC10 gene location on human chromosome 12.png|thumb|right|300px|Location of the HOXC10 gene on human chromosome 12.]]


== See Also ==
== See Also ==
* [[Homeobox]]
* [[Homeobox]]
* [[Hox gene]]
* [[HOX gene]]
* [[Transcription factor]]
* [[Transcription factor]]
* [[Breast cancer]]
* [[Embryonic development]]
* [[Ovarian cancer]]
* [[Endometriosis]]


== References ==
== References ==
<references />
<references/>


[[Category:Genes]]
== External Links ==
[[Category:Human proteins]]
* [https://www.ncbi.nlm.nih.gov/gene/HOXC10 HOXC10 Gene - NCBI]
* [https://www.genecards.org/cgi-bin/carddisp.pl?gene=HOXC10 GeneCards: HOXC10]
 
[[Category:Genes on human chromosome 12]]
[[Category:Transcription factors]]
[[Category:Transcription factors]]
[[Category:Homeobox genes]]
[[Category:Developmental genes and proteins]]
[[Category:Medical genetics]]
 
{{medicine-stub}}

Latest revision as of 20:42, 30 December 2024


HOXC10
Symbol HOXC10
HGNC ID 5115
Alternative symbols
Entrez Gene
OMIM
RefSeq
UniProt
Chromosome 12q13.13
Locus supplementary data


HOXC10 is a gene that encodes a homeobox protein involved in the regulation of developmental processes. It is part of the HOX gene family, which plays a crucial role in embryonic development and the anterior-posterior axis formation.

Function[edit]

The HOXC10 gene is a member of the homeobox family of genes, which are known for their role in regulating patterns of anatomical development (morphogenesis) in animals, fungi, and plants. The protein encoded by HOXC10 is a transcription factor that binds to specific DNA sequences, thereby controlling the expression of other genes. This gene is particularly important in the development of the spinal cord, limbs, and urogenital system.

Clinical Significance[edit]

Mutations or dysregulation of the HOXC10 gene have been associated with various developmental disorders and cancers. Studies have shown that abnormal expression of HOXC10 may contribute to the progression of certain types of breast cancer and ovarian cancer.

Research[edit]

Research on HOXC10 continues to explore its role in oncogenesis and its potential as a biomarker for certain cancers. Understanding the mechanisms by which HOXC10 influences cell proliferation and differentiation could lead to new therapeutic targets.

See Also[edit]

References[edit]

<references/>

External Links[edit]