Ethyltestosterone: Difference between revisions

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'''Ethyltestosterone''', also known by its chemical name 17α-ethyltestosterone, is a synthetic, orally active [[androgen]] and [[anabolic steroid]] (AAS) which has been used in medical treatments but is more commonly associated with performance enhancement in sports and bodybuilding. Despite its potential therapeutic applications, the use of ethyltestosterone in clinical settings is limited due to its side effects and the availability of more effective treatments.
{{Short description|Synthetic anabolic-androgenic steroid}}
{{DISPLAYTITLE:''Ethyltestosterone''}}
 
[[File:Ethyltestosterone_structure.png|thumb|right|Chemical structure of Ethyltestosterone]]
 
'''Ethyltestosterone''' is a synthetic [[anabolic-androgenic steroid]] (AAS) that is derived from [[testosterone]]. It is characterized by the presence of an ethyl group at the 17α position of the steroid structure. This modification alters the pharmacokinetics and biological activity of the compound compared to its parent hormone, testosterone.
 
==Chemical Structure and Properties==
Ethyltestosterone, also known by its chemical name 17α-ethylandrost-4-en-17β-ol-3-one, is a [[C19H30O2|C19H30O2]] compound. The addition of the ethyl group at the 17α position is a common modification in the synthesis of oral anabolic steroids, as it enhances the oral bioavailability of the compound by reducing its susceptibility to hepatic metabolism.
 
==Pharmacology==
Ethyltestosterone exhibits both [[androgenic]] and [[anabolic]] properties. The androgenic effects are related to the development and maintenance of male characteristics, while the anabolic effects promote protein synthesis and muscle growth. The balance between these effects is crucial in determining the therapeutic and side effect profile of the steroid.
 
===Mechanism of Action===
Like other anabolic steroids, ethyltestosterone exerts its effects by binding to the [[androgen receptor]] in target tissues. This binding initiates a cascade of events that lead to increased transcription of specific genes, resulting in enhanced protein synthesis and muscle growth.


==Medical Uses==
==Medical Uses==
Ethyltestosterone was explored for use in various medical conditions requiring androgen replacement therapy. It has been investigated for the treatment of conditions such as [[hypogonadism]] in men, certain types of [[breast cancer]] in women, and as part of the hormone therapy for transgender men. However, its use in modern medicine has largely been superseded by newer agents with improved safety profiles and more selective androgen receptor activity.
Ethyltestosterone has been used in the past for various medical conditions, including [[hypogonadism]], delayed puberty in males, and certain types of [[anemia]]. However, its use has declined due to the development of newer steroids with more favorable safety profiles.
 
==Mechanism of Action==
As an analog of [[testosterone]], ethyltestosterone exerts its effects by binding to and activating the androgen receptor (AR). This leads to AR-mediated effects on protein synthesis, muscle growth, and erythropoiesis, among other physiological processes. The ethyl group at the 17α-position increases the oral bioavailability of the compound, making it effective when taken by mouth.


==Side Effects==
==Side Effects==
The side effects of ethyltestosterone are similar to those of other AAS. These can include, but are not limited to, hepatotoxicity, changes in lipid profiles, increased risk of cardiovascular disease, virilization in women, and suppression of natural testosterone production in men. The severity of side effects is dose-dependent and can also be influenced by individual susceptibility.
The use of ethyltestosterone, like other anabolic steroids, can lead to a range of side effects. These may include [[liver toxicity]], [[cardiovascular issues]], [[hormonal imbalances]], and [[psychiatric effects]]. Long-term use can also result in [[testicular atrophy]] and [[infertility]] in males.


==Legal Status==
==Legal Status==
The legal status of ethyltestosterone varies by country, but it is generally classified as a controlled substance due to its potential for abuse and health risks. In many jurisdictions, its use, possession, or distribution without a prescription is illegal.
Ethyltestosterone is classified as a controlled substance in many countries due to its potential for abuse and adverse health effects. It is included in the list of substances banned by the [[World Anti-Doping Agency]] (WADA) for use in sports.
 
==In Sports==
Ethyltestosterone has been used by athletes and bodybuilders to enhance muscle mass, strength, and endurance. However, its use is banned by most major sports organizations, including the [[World Anti-Doping Agency]] (WADA). Detection of ethyltestosterone or its metabolites in drug tests can lead to sanctions against athletes.


==Conclusion==
==Related Pages==
While ethyltestosterone has historical significance in the development of AAS, its clinical use is limited today due to the availability of safer and more effective treatment options. Its potential for abuse and associated health risks further restrict its use in both medical and non-medical contexts.
* [[Anabolic steroid]]
* [[Testosterone]]
* [[Androgen receptor]]
* [[Hypogonadism]]


[[Category:Anabolic steroids]]
[[Category:Androgens and anabolic steroids]]
[[Category:Androgens and anabolic steroids]]
[[Category:Performance-enhancing substances]]
[[Category:Ketones]]
 
{{medicine-stub}}
 
== Ethyltestosterone ==
<gallery>
File:Ethyltestosterone structure.png|Ethyltestosterone structure
</gallery>
== Ethyltestosterone ==
<gallery>
File:Ethyltestosterone structure.png|Ethyltestosterone structure
</gallery>

Latest revision as of 11:44, 23 March 2025

Synthetic anabolic-androgenic steroid



Chemical structure of Ethyltestosterone

Ethyltestosterone is a synthetic anabolic-androgenic steroid (AAS) that is derived from testosterone. It is characterized by the presence of an ethyl group at the 17α position of the steroid structure. This modification alters the pharmacokinetics and biological activity of the compound compared to its parent hormone, testosterone.

Chemical Structure and Properties[edit]

Ethyltestosterone, also known by its chemical name 17α-ethylandrost-4-en-17β-ol-3-one, is a C19H30O2 compound. The addition of the ethyl group at the 17α position is a common modification in the synthesis of oral anabolic steroids, as it enhances the oral bioavailability of the compound by reducing its susceptibility to hepatic metabolism.

Pharmacology[edit]

Ethyltestosterone exhibits both androgenic and anabolic properties. The androgenic effects are related to the development and maintenance of male characteristics, while the anabolic effects promote protein synthesis and muscle growth. The balance between these effects is crucial in determining the therapeutic and side effect profile of the steroid.

Mechanism of Action[edit]

Like other anabolic steroids, ethyltestosterone exerts its effects by binding to the androgen receptor in target tissues. This binding initiates a cascade of events that lead to increased transcription of specific genes, resulting in enhanced protein synthesis and muscle growth.

Medical Uses[edit]

Ethyltestosterone has been used in the past for various medical conditions, including hypogonadism, delayed puberty in males, and certain types of anemia. However, its use has declined due to the development of newer steroids with more favorable safety profiles.

Side Effects[edit]

The use of ethyltestosterone, like other anabolic steroids, can lead to a range of side effects. These may include liver toxicity, cardiovascular issues, hormonal imbalances, and psychiatric effects. Long-term use can also result in testicular atrophy and infertility in males.

Legal Status[edit]

Ethyltestosterone is classified as a controlled substance in many countries due to its potential for abuse and adverse health effects. It is included in the list of substances banned by the World Anti-Doping Agency (WADA) for use in sports.

Related Pages[edit]