Mucoepidermoid carcinoma: Difference between revisions
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{{Infobox medical condition | |||
| name = Mucoepidermoid carcinoma | |||
| image = [[File:Mucoepidermoid_carcinoma_2_-_very_high_mag.jpg|left|thumb|alt=Micrograph of mucoepidermoid carcinoma]] | |||
| caption = Micrograph of mucoepidermoid carcinoma | |||
| field = [[Oncology]] | |||
| synonyms = | |||
| symptoms = [[Lump]] in the [[salivary gland]], [[pain]], [[difficulty swallowing]] | |||
| complications = [[Metastasis]], [[nerve damage]] | |||
| onset = | |||
| duration = | |||
| types = Low-grade, intermediate-grade, high-grade | |||
| causes = | |||
| risks = [[Radiation exposure]], [[genetic predisposition]] | |||
| diagnosis = [[Biopsy]], [[imaging studies]] | |||
| differential = [[Adenoid cystic carcinoma]], [[pleomorphic adenoma]] | |||
| prevention = | |||
| treatment = [[Surgery]], [[radiation therapy]], [[chemotherapy]] | |||
| medication = | |||
| prognosis = Depends on grade and stage | |||
| frequency = Most common [[salivary gland]] malignancy | |||
}} | |||
[[File:Mucoepidermoid_carcinoma_(2)_HE_stain.jpg|thumb|Mucoepidermoid carcinoma with H&E stain]] | |||
[[File:Mucoepidermoid_carcinoma_(3)_HE_stain.jpg|left|thumb|Mucoepidermoid carcinoma with H&E stain]] | |||
[[File:Mucoepidermoid_carcinoma_(1)_AB-PAS_stain.jpg|left|thumb|Mucoepidermoid carcinoma with AB-PAS stain]] | |||
[[File:Relative_incidence_of_parotid_tumors.png|left|thumb|Relative incidence of parotid tumors]] | |||
[[File:Relative_incidence_of_submandibular_tumors.png|left|thumb|Relative incidence of submandibular tumors]] | |||
'''Mucoepidermoid carcinoma''' ('''MEC''') is a type of [[cancer]] that originates from the [[salivary glands]]. It is the most common type of [[malignancy]] found in the salivary glands. | '''Mucoepidermoid carcinoma''' ('''MEC''') is a type of [[cancer]] that originates from the [[salivary glands]]. It is the most common type of [[malignancy]] found in the salivary glands. | ||
==Epidemiology== | ==Epidemiology== | ||
MEC is most commonly found in adults between the ages of 30 and 50, but it can also occur in children. It is slightly more common in women than in men. | MEC is most commonly found in adults between the ages of 30 and 50, but it can also occur in children. It is slightly more common in women than in men. | ||
==Pathophysiology== | ==Pathophysiology== | ||
MEC arises from the [[exocrine glands]], which are glands that secrete substances onto an epithelial surface by way of a duct. The tumor is composed of a mixture of cell types, including mucous-secreting cells and squamous cells. | MEC arises from the [[exocrine glands]], which are glands that secrete substances onto an epithelial surface by way of a duct. The tumor is composed of a mixture of cell types, including mucous-secreting cells and squamous cells. | ||
==Clinical Presentation== | ==Clinical Presentation== | ||
Patients with MEC often present with a painless mass in the [[parotid gland]], which is the largest of the salivary glands. Other symptoms can include facial nerve paralysis, pain, and skin involvement. | Patients with MEC often present with a painless mass in the [[parotid gland]], which is the largest of the salivary glands. Other symptoms can include facial nerve paralysis, pain, and skin involvement. | ||
==Diagnosis== | ==Diagnosis== | ||
The diagnosis of MEC is typically made through a combination of physical examination, imaging studies, and biopsy. [[Histopathology]] is used to confirm the diagnosis and to determine the grade of the tumor. | The diagnosis of MEC is typically made through a combination of physical examination, imaging studies, and biopsy. [[Histopathology]] is used to confirm the diagnosis and to determine the grade of the tumor. | ||
==Treatment== | ==Treatment== | ||
The primary treatment for MEC is surgical removal of the tumor. [[Radiation therapy]] may also be used, particularly in cases where the tumor is high-grade or if it has spread to the lymph nodes. | The primary treatment for MEC is surgical removal of the tumor. [[Radiation therapy]] may also be used, particularly in cases where the tumor is high-grade or if it has spread to the lymph nodes. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for MEC varies depending on the grade of the tumor and the extent of disease at the time of diagnosis. Low-grade tumors have a good prognosis, with a 5-year survival rate of over 90%. High-grade tumors have a poorer prognosis, with a 5-year survival rate of less than 50%. | The prognosis for MEC varies depending on the grade of the tumor and the extent of disease at the time of diagnosis. Low-grade tumors have a good prognosis, with a 5-year survival rate of over 90%. High-grade tumors have a poorer prognosis, with a 5-year survival rate of less than 50%. | ||
==See Also== | ==See Also== | ||
* [[Salivary gland neoplasm]] | * [[Salivary gland neoplasm]] | ||
* [[Adenoid cystic carcinoma]] | * [[Adenoid cystic carcinoma]] | ||
* [[Acinic cell carcinoma]] | * [[Acinic cell carcinoma]] | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Oral pathology]] | [[Category:Oral pathology]] | ||
[[Category:Salivary gland pathology]] | [[Category:Salivary gland pathology]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 00:59, 14 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Mucoepidermoid carcinoma | |
|---|---|
 | |
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Lump in the salivary gland, pain, difficulty swallowing |
| Complications | Metastasis, nerve damage |
| Onset | |
| Duration | |
| Types | Low-grade, intermediate-grade, high-grade |
| Causes | |
| Risks | Radiation exposure, genetic predisposition |
| Diagnosis | Biopsy, imaging studies |
| Differential diagnosis | Adenoid cystic carcinoma, pleomorphic adenoma |
| Prevention | |
| Treatment | Surgery, radiation therapy, chemotherapy |
| Medication | |
| Prognosis | Depends on grade and stage |
| Frequency | Most common salivary gland malignancy |
| Deaths | N/A |
_HE_stain.jpg)
_HE_stain.jpg)
_AB-PAS_stain.jpg)
Mucoepidermoid carcinoma (MEC) is a type of cancer that originates from the salivary glands. It is the most common type of malignancy found in the salivary glands.
Epidemiology[edit]
MEC is most commonly found in adults between the ages of 30 and 50, but it can also occur in children. It is slightly more common in women than in men.
Pathophysiology[edit]
MEC arises from the exocrine glands, which are glands that secrete substances onto an epithelial surface by way of a duct. The tumor is composed of a mixture of cell types, including mucous-secreting cells and squamous cells.
Clinical Presentation[edit]
Patients with MEC often present with a painless mass in the parotid gland, which is the largest of the salivary glands. Other symptoms can include facial nerve paralysis, pain, and skin involvement.
Diagnosis[edit]
The diagnosis of MEC is typically made through a combination of physical examination, imaging studies, and biopsy. Histopathology is used to confirm the diagnosis and to determine the grade of the tumor.
Treatment[edit]
The primary treatment for MEC is surgical removal of the tumor. Radiation therapy may also be used, particularly in cases where the tumor is high-grade or if it has spread to the lymph nodes.
Prognosis[edit]
The prognosis for MEC varies depending on the grade of the tumor and the extent of disease at the time of diagnosis. Low-grade tumors have a good prognosis, with a 5-year survival rate of over 90%. High-grade tumors have a poorer prognosis, with a 5-year survival rate of less than 50%.
