Dimetindene: Difference between revisions
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Latest revision as of 01:00, 20 February 2025
An article about the antihistamine drug Dimetindene
Dimetindene is an antihistamine and anticholinergic medication used primarily for the treatment of allergic reactions, such as hay fever, urticaria, and pruritus. It is also used in topical formulations for the relief of itching and irritation associated with skin conditions.
Pharmacology[edit]
Dimetindene is a selective histamine H1 receptor antagonist. By blocking the action of histamine, it reduces the symptoms associated with allergic reactions, such as swelling, redness, and itching. It also exhibits some anticholinergic properties, which contribute to its effectiveness in reducing nasal secretions and other symptoms of allergies.
Uses[edit]
Dimetindene is used in the management of various allergic conditions, including:
- Allergic rhinitis (hay fever)
- Urticaria (hives)
- Pruritus (itching)
- Eczema and other skin irritations
It is available in oral and topical forms, allowing for flexibility in treatment depending on the severity and location of symptoms.
Side Effects[edit]
Common side effects of dimetindene include:
Less common side effects may include:
Mechanism of Action[edit]
Dimetindene works by competitively inhibiting the binding of histamine to the H1 receptor. This prevents the cascade of events that lead to the symptoms of an allergic reaction. Its anticholinergic effects are due to its ability to block muscarinic acetylcholine receptors, which helps reduce nasal secretions and other symptoms.
Formulations[edit]
Dimetindene is available in several formulations, including:
- Oral tablets
- Oral drops
- Topical gels and creams
These formulations allow for both systemic and localized treatment of allergic symptoms.
Related pages[edit]
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Dimetindene
