ATC code A04

ATC code A04 is a section of the Anatomical Therapeutic Chemical Classification System (ATC), a system used for the classification of drugs and other medical products. This section is specifically designated for antiemetics and antinauseants, which are medications used to prevent and treat nausea and vomiting.

Classification

The ATC code A04 is divided into several subgroups, each representing a different class of antiemetic and antinauseant medications. These subgroups include:

• A04A - Antiemetics and antinauseants

A04AA - Serotonin (5-HT3) antagonists

• A04AA01 - Ondansetron
• A04AA02 - Granisetron
• A04AA03 - Tropisetron
• A04AA04 - Dolasetron
• A04AA05 - Palonosetron

A04AB - Dopamine antagonists

• A04AB01 - Metoclopramide
• A04AB02 - Domperidone
• A04AB03 - Droperidol

A04AC - Other antiemetics

• A04AC01 - Aprepitant
• A04AC02 - Fosaprepitant
• A04AC03 - Netupitant
• A04AC04 - Rolapitant

Uses

Antiemetics and antinauseants are used in various medical conditions and treatments, including:

• Chemotherapy-induced nausea and vomiting
• Postoperative nausea and vomiting
• Motion sickness
• Gastroenteritis

Mechanism of Action

Different classes of antiemetics work through various mechanisms to prevent nausea and vomiting:

• Serotonin antagonists block the action of serotonin at 5-HT3 receptors in the central nervous system and gastrointestinal tract.
• Dopamine antagonists block dopamine receptors in the brain, particularly in the chemoreceptor trigger zone.
• Other antiemetics may work through different pathways, including neurokinin-1 receptor antagonists and antihistamines.

See Also

• ATC code A
• Nausea
• Vomiting
• Chemotherapy
• Postoperative care

External Links

ATC codes
A Alimentary tract and metabolism
A01 Stomatological preparations
A02 Drugs for acid related disorders
A03 Drugs for functional gastrointestinal disorders
A04 Antiemetics and antinauseants
A05 Bile and liver therapy
A06 Drugs for constipation
A07 Antidiarrheals, intestinal anti-inflammatory/anti-infective agents
A08 Antiobesity preparations, excluding diet products
A09 Digestives, including enzymes
A10 Drugs used in diabetes
A11 Vitamins
A12 Mineral supplements
A13 Tonics
A14 Anabolic agents for systemic use
A15 Appetite stimulants
A16 Other alimentary tract and metabolism products
A B C D G H QI J L M N P R S V (Hover over links to see titles)

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