Dimetindene: Difference between revisions

Dimetindene
	File:Dimetindene.svg
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Revision as of 04:00, 13 February 2025

An article about the antihistamine drug Dimetindene

Dimetindene is an antihistamine and anticholinergic medication used primarily for the treatment of allergic reactions, such as hay fever, urticaria, and pruritus. It is also used in topical formulations for the relief of itching and irritation associated with skin conditions.

Pharmacology

Dimetindene is a selective histamine H1 receptor antagonist. By blocking the action of histamine, it reduces the symptoms associated with allergic reactions, such as swelling, redness, and itching. It also exhibits some anticholinergic properties, which contribute to its effectiveness in reducing nasal secretions and other symptoms of allergies.

Uses

Dimetindene is used in the management of various allergic conditions, including:

Allergic rhinitis (hay fever)
Urticaria (hives)
Pruritus (itching)
Eczema and other skin irritations

It is available in oral and topical forms, allowing for flexibility in treatment depending on the severity and location of symptoms.

Side Effects

Common side effects of dimetindene include:

Less common side effects may include:

Mechanism of Action

Dimetindene works by competitively inhibiting the binding of histamine to the H1 receptor. This prevents the cascade of events that lead to the symptoms of an allergic reaction. Its anticholinergic effects are due to its ability to block muscarinic acetylcholine receptors, which helps reduce nasal secretions and other symptoms.

Formulations

Dimetindene is available in several formulations, including:

Oral tablets
Oral drops
Topical gels and creams

These formulations allow for both systemic and localized treatment of allergic symptoms.

Related pages

@@ Line 1: / Line 1: @@
-'''Dimetindene''' is an [[antihistamine]] with [[anticholinergic]] properties that is marketed under the trade names ''Fenistil'' among others. It is used for the treatment of [[allergies]] and [[pruritus]].
+{{Short description|An article about the antihistamine drug Dimetindene}}
+{{Drugbox
+| image = Dimetindene.svg
+| image_size = 200px
+| image_alt = Structural formula of Dimetindene
+}}
-==Medical uses==
+'''Dimetindene''' is an [[antihistamine]] and [[anticholinergic]] medication used primarily for the treatment of [[allergic reactions]], such as [[hay fever]], [[urticaria]], and [[pruritus]]. It is also used in topical formulations for the relief of itching and irritation associated with skin conditions.
-Dimetindene is used for the treatment of allergies such as [[hay fever]] or [[urticaria]]. It is also used for the treatment of pruritus, a symptom of various conditions such as [[dermatitis]] and [[jaundice]].
 ==Pharmacology==
-Dimetindene is an antihistamine, which means it works by blocking the action of [[histamine]], a substance in the body that causes allergic symptoms. It also has anticholinergic properties, which means it can help to reduce the effects of [[acetylcholine]], a neurotransmitter that can cause symptoms such as muscle spasms and increased heart rate.
+Dimetindene is a selective [[histamine H1 receptor]] antagonist. By blocking the action of histamine, it reduces the symptoms associated with allergic reactions, such as swelling, redness, and itching. It also exhibits some [[anticholinergic]] properties, which contribute to its effectiveness in reducing nasal secretions and other symptoms of allergies.
-==Side effects==
+==Uses==
-Common side effects of dimetindene include [[drowsiness]], [[dizziness]], and [[dry mouth]]. In rare cases, it can cause more serious side effects such as [[confusion]], [[hallucinations]], and [[tachycardia]].
+Dimetindene is used in the management of various allergic conditions, including:
-==Interactions==
+* [[Allergic rhinitis]] (hay fever)
-Dimetindene can interact with other medications, including other antihistamines, [[antidepressants]], and [[antipsychotics]]. It can also interact with certain foods and drinks, such as alcohol.
+* [[Urticaria]] (hives)
+* [[Pruritus]] (itching)
+* [[Eczema]] and other skin irritations
-==See also==
+It is available in oral and topical forms, allowing for flexibility in treatment depending on the severity and location of symptoms.
+==Side Effects==
+Common side effects of dimetindene include:
+* [[Drowsiness]]
+* [[Dry mouth]]
+* [[Dizziness]]
+Less common side effects may include:
+* [[Gastrointestinal disturbances]]
+* [[Headache]]
+* [[Blurred vision]]
+==Mechanism of Action==
+Dimetindene works by competitively inhibiting the binding of histamine to the H1 receptor. This prevents the cascade of events that lead to the symptoms of an allergic reaction. Its anticholinergic effects are due to its ability to block [[muscarinic acetylcholine receptors]], which helps reduce nasal secretions and other symptoms.
+==Formulations==
+Dimetindene is available in several formulations, including:
+* Oral tablets
+* Oral drops
+* Topical gels and creams
+These formulations allow for both systemic and localized treatment of allergic symptoms.
+==Related pages==
 * [[Antihistamine]]
-* [[Anticholinergic]]
+* [[Allergic reaction]]
-* [[Pruritus]]
+* [[Histamine]]
-==References==
-<references />
 [[Category:Antihistamines]]
 [[Category:Anticholinergics]]
-[[Category:Medications]]
-{{stub}}