Gluconic acid: Difference between revisions

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'''Gluconic acid''' is an organic compound with the formula HOCH<sub>2</sub>(CHOH)<sub>4</sub>CO<sub>2</sub>H. It is a type of [[carboxylic acid]] and is derived from [[glucose]], a type of [[sugar]]. Gluconic acid is naturally present in fruit, honey, and wine.
{{Short description|A carboxylic acid derived from glucose}}
{{DISPLAYTITLE:Gluconic acid}}


==Chemical Structure==
==Gluconic acid==
Gluconic acid has a chemical structure that consists of a six-carbon chain, with five hydroxyl groups and one carboxyl group. The presence of the carboxyl group makes it an acid. The five hydroxyl groups make it a polyol, a type of alcohol with multiple hydroxyl groups.
[[File:D-Gluconsäure_Keilstrich.svg|thumb|right|Structural formula of D-Gluconic acid]]
'''Gluconic acid''' is an [[organic compound]] with the formula C_H__O_. It is a [[carboxylic acid]] derived from [[glucose]] by the oxidation of the aldehyde group at C-1 to a carboxyl group. This compound is widely found in nature as it occurs in fruit, honey, and wine. It is also produced by the fermentation of glucose by certain bacteria.
 
==Chemical properties==
Gluconic acid is a mild organic acid that forms when glucose is oxidized. It is soluble in water and has a slightly sweet taste. The acid exists in equilibrium with its lactone form, [[glucono delta-lactone]], which is a cyclic ester. This equilibrium is pH-dependent, with the lactone form being favored in acidic conditions.
 
==Biological role==
In biological systems, gluconic acid plays a role in the [[pentose phosphate pathway]], which is crucial for the production of [[NADPH]] and [[ribose 5-phosphate]]. It is also involved in the [[metabolism]] of glucose in certain microorganisms, where it serves as a source of carbon and energy.
 
==Industrial applications==
Gluconic acid and its salts, known as [[gluconates]], have various industrial applications. They are used as [[chelating agents]] to bind metal ions, which is useful in cleaning products and water treatment. In the food industry, gluconic acid is used as an [[acidulant]] and a [[sequestrant]]. It is also used in the pharmaceutical industry for its ability to enhance the absorption of certain drugs.


==Production==
==Production==
Gluconic acid is produced industrially by the fermentation of glucose with the fungus ''[[Aspergillus niger]]''. The glucose is oxidized to gluconic acid, with the reduction of oxygen to water. This process is used to produce a variety of gluconate products, including [[sodium gluconate]], [[calcium gluconate]], and [[potassium gluconate]].
Gluconic acid is produced commercially by the fermentation of glucose using [[Aspergillus niger]] or other fungi. The process involves the oxidation of glucose by the enzyme glucose oxidase, which converts the aldehyde group of glucose to a carboxylic acid group.


==Uses==
==Related compounds==
Gluconic acid and its derivatives are used in a variety of applications. They are used as a [[pH]] regulator in food and drink, as a cleaning agent in the dairy industry, and as a chelating agent in various industrial applications. In medicine, gluconic acid is used in the form of [[calcium gluconate]] and [[sodium gluconate]] to treat calcium and sodium deficiencies, respectively.
* [[Glucono delta-lactone]]
* [[Gluconate]]
* [[Glucose]]
* [[Ascorbic acid]]


==Health Effects==
==Related pages==
Gluconic acid is generally recognized as safe (GRAS) by the [[Food and Drug Administration|FDA]]. However, excessive consumption can lead to gastrointestinal disturbances, including nausea and diarrhea.
 
==See Also==
* [[Carboxylic acid]]
* [[Carboxylic acid]]
* [[Glucose]]
* [[Pentose phosphate pathway]]
* [[Aspergillus niger]]
* [[Fermentation]]
* [[Sodium gluconate]]
* [[Calcium gluconate]]
* [[Potassium gluconate]]
* [[Food and Drug Administration|FDA]]


[[Category:Carboxylic acids]]
[[Category:Organic compounds]]
[[Category:Organic compounds]]
[[Category:Carboxylic acids]]
[[Category:Food additives]]
[[Category:Food additives]]
[[Category:Industrial chemicals]]
[[Category:Medicine]]
{{stub}}

Latest revision as of 05:14, 16 February 2025

A carboxylic acid derived from glucose



Gluconic acid[edit]

Structural formula of D-Gluconic acid

Gluconic acid is an organic compound with the formula C_H__O_. It is a carboxylic acid derived from glucose by the oxidation of the aldehyde group at C-1 to a carboxyl group. This compound is widely found in nature as it occurs in fruit, honey, and wine. It is also produced by the fermentation of glucose by certain bacteria.

Chemical properties[edit]

Gluconic acid is a mild organic acid that forms when glucose is oxidized. It is soluble in water and has a slightly sweet taste. The acid exists in equilibrium with its lactone form, glucono delta-lactone, which is a cyclic ester. This equilibrium is pH-dependent, with the lactone form being favored in acidic conditions.

Biological role[edit]

In biological systems, gluconic acid plays a role in the pentose phosphate pathway, which is crucial for the production of NADPH and ribose 5-phosphate. It is also involved in the metabolism of glucose in certain microorganisms, where it serves as a source of carbon and energy.

Industrial applications[edit]

Gluconic acid and its salts, known as gluconates, have various industrial applications. They are used as chelating agents to bind metal ions, which is useful in cleaning products and water treatment. In the food industry, gluconic acid is used as an acidulant and a sequestrant. It is also used in the pharmaceutical industry for its ability to enhance the absorption of certain drugs.

Production[edit]

Gluconic acid is produced commercially by the fermentation of glucose using Aspergillus niger or other fungi. The process involves the oxidation of glucose by the enzyme glucose oxidase, which converts the aldehyde group of glucose to a carboxylic acid group.

Related compounds[edit]

Related pages[edit]