Poikiloderma: Difference between revisions

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{{Infobox medical condition (new)
 
| name           = <!--{{PAGENAME}} by default-->
{{Infobox medical condition
| synonym        =  
| name = Poikiloderma
| image          = File:Rothmund-Thomson syndrome.jpg
| image = <!-- Image removed -->
| image_size      =  
| caption = <!-- Caption removed -->
| alt            =  
| field = [[Dermatology]]
| caption        = People with varying manifestations of poikiloderma
| synonyms =  
| pronounce      =
| symptoms = [[Skin atrophy]], [[telangiectasia]], [[hyperpigmentation]], [[hypopigmentation]]
| specialty      = dermatology
| complications =  
| symptoms       =
| onset =  
| complications   =
| duration =  
| onset           =
| causes = [[Genetic disorders]], [[environmental factors]]
| duration       =
| risks =  
| types          =  
| diagnosis = [[Clinical examination]], [[biopsy]]
| causes         =
| differential = [[Lupus erythematosus]], [[scleroderma]]
| risks           =
| treatment = [[Sun protection]], [[topical treatments]]
| diagnosis       =
| medication =  
| differential   =
| prognosis =  
| prevention      =
| frequency =  
| treatment       =
| medication     =
| prognosis       =
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}}
}}
'''Poikiloderma''' is a skin condition that consists of areas of [[hypopigmentation]], [[hyperpigmentation]], [[telangiectasias]] and [[atrophy]].
Poikiloderma of Civatte is most frequently seen on the chest or the neck, characterized by red colored pigment on the skin that is commonly associated with sun damage.<ref>{{cite book|last1=Raulin|first1=Christian|last2=Karsai|first2=Syrus|title=Laser and IPL Technology in Dermatology and Aesthetic Medicine|date=2011|publisher=Springer Science & Business Media|isbn=9783642034381|page=236|url=https://books.google.com/?id=yY7fz5J4g4sC&dq=Poikiloderma+check+neck|accessdate=7 March 2018|language=en}}</ref>
==Types==
* [[Poikiloderma vasculare atrophicans]]
* [[Poikiloderma of Civatte]]
* [[Hereditary sclerosing poikiloderma]]
==Causes==
*Congenital
#[[Rothmund-Thompson syndrome]]
#[[Dyskeratosis congenita]]
#[[Mendes da Costa syndrome]]
*Other hereditary causes
#[[Degos-Touraine syndrome]]
#Diffuse and macular atrophic [[dermatosis]]
#[[Hereditary sclerosing poikiloderma]] of weary
#[[Kindler syndrome]]
#[[Weary-Kindler syndrome]]
#[[Xeroderma pigmentosum]]


*Acquired
'''Poikiloderma''' is a condition characterized by changes in the skin, including [[atrophy]], [[telangiectasia]], and variations in pigmentation such as [[hyperpigmentation]] and [[hypopigmentation]]. It is often a result of [[genetic disorders]] or [[environmental factors]].
#Injury to cold, heat, ionizing radiation, exposure to sensitizing chemicals
#[[Lichen planus]]
#[[Dermatomyositis]]
#[[Lupus erythematosus]]
#[[Systemic sclerosis]]
#[[Cutaneous T cell lymphoma]]s


==Pathogenesis==
== Signs and Symptoms ==
The exact cause of poikiloderma of Civatte is unknown; however, extended sun exposure, namely the [[ultraviolet light]] emitted by the sun, is the primary factor.<ref>American Osteopathic College of Dermatology [http://www.aocd.org/skin/dermatologic_diseases/Poikiloderma-of-Civatte.html "Dermatologic Disease Database"], ''aocd.org'', referenced July 22, 2011.</ref>
Poikiloderma presents with a combination of skin changes:
* [[Skin atrophy]] - thinning of the skin
* [[Telangiectasia]] - visible small blood vessels
* [[Hyperpigmentation]] - darkening of the skin
* [[Hypopigmentation]] - lightening of the skin


==Diagnosis==
== Causes ==
{{Empty section|date=July 2018}}
The causes of poikiloderma can be varied and include:
* [[Genetic disorders]] such as [[Rothmund-Thomson syndrome]], [[Bloom syndrome]], and [[Dyskeratosis congenita]].
* [[Environmental factors]] like chronic sun exposure, which can lead to [[actinic damage]].


==Treatment==
== Diagnosis ==
Albeit difficult, treatment of poikiloderma of Civatte involves the delivery of multiple wavelengths of intense pulsed light (IPL) to the affected area.<ref>PubMed.gov [https://www.ncbi.nlm.nih.gov/pubmed/11335804 "Treatment of poikiloderma of Civatte with an intense pulsed light source"], ''PubMed.gov'', referenced July 22, 2011.</ref>
Diagnosis of poikiloderma is primarily clinical, based on the appearance of the skin. A [[biopsy]] may be performed to rule out other conditions and confirm the diagnosis.


==See also==
== Differential Diagnosis ==
* [[Osteopoikilosis]]
Conditions that may present similarly to poikiloderma include:
* [[List of cutaneous conditions]]
* [[Lupus erythematosus]]
* [[Scleroderma]]
* [[Dermatomyositis]]


==References==
== Treatment ==
{{Reflist}}
Management of poikiloderma focuses on:
* [[Sun protection]] to prevent further damage
* [[Topical treatments]] such as [[retinoids]] or [[steroids]] to improve skin appearance


{{pigmentation disorders}}
== See Also ==
* [[Dermatology]]
* [[Genetic disorders]]
* [[Skin pigmentation]]


[[Category:Disturbances of human pigmentation]]
== References ==
<references/>


== External Links ==
* [Poikiloderma at DermNet NZ](https://dermnetnz.org/topics/poikiloderma/)


{{Cutaneous-condition-stub}}
[[Category:Dermatology]]
[[Category:Genetic disorders]]
[[Category:Skin conditions]]
<gallery>
File:Rothmund-Thomson_syndrome.jpg|Rothmund-Thomson syndrome
</gallery>

Latest revision as of 21:32, 20 February 2025


Poikiloderma
Synonyms
Pronounce N/A
Specialty N/A
Symptoms Skin atrophy, telangiectasia, hyperpigmentation, hypopigmentation
Complications
Onset
Duration
Types N/A
Causes Genetic disorders, environmental factors
Risks
Diagnosis Clinical examination, biopsy
Differential diagnosis Lupus erythematosus, scleroderma
Prevention N/A
Treatment Sun protection, topical treatments
Medication
Prognosis
Frequency
Deaths N/A


Poikiloderma is a condition characterized by changes in the skin, including atrophy, telangiectasia, and variations in pigmentation such as hyperpigmentation and hypopigmentation. It is often a result of genetic disorders or environmental factors.

Signs and Symptoms[edit]

Poikiloderma presents with a combination of skin changes:

Causes[edit]

The causes of poikiloderma can be varied and include:

Diagnosis[edit]

Diagnosis of poikiloderma is primarily clinical, based on the appearance of the skin. A biopsy may be performed to rule out other conditions and confirm the diagnosis.

Differential Diagnosis[edit]

Conditions that may present similarly to poikiloderma include:

Treatment[edit]

Management of poikiloderma focuses on:

See Also[edit]

References[edit]

<references/>

External Links[edit]

  • Rothmund-Thomson syndrome
    Rothmund-Thomson syndrome
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