Infiltrative ophthalmopathy: Difference between revisions

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{{Infobox medical condition
| name            = Infiltrative ophthalmopathy
| synonyms        = Thyroid eye disease, Graves' ophthalmopathy
| field          = [[Ophthalmology]], [[Endocrinology]]
| symptoms        = [[Exophthalmos]], [[diplopia]], [[eye irritation]], [[lid retraction]], [[periorbital edema]]
| complications  = [[Corneal ulcer]], [[vision loss]]
| onset          = Typically between ages 30 and 50
| duration        = Variable, can be chronic
| causes          = [[Autoimmune disorder]], often associated with [[Graves' disease]]
| risks          = [[Smoking]], [[female]] gender, [[radioiodine therapy]]
| diagnosis      = [[Clinical examination]], [[imaging studies]] such as [[CT scan]] or [[MRI]]
| differential    = [[Orbital cellulitis]], [[orbital tumor]], [[idiopathic orbital inflammation]]
| treatment      = [[Corticosteroids]], [[orbital decompression surgery]], [[radiotherapy]], [[immunosuppressive therapy]]
| medication      = [[Prednisone]], [[methimazole]], [[propylthiouracil]]
| frequency      = Affects approximately 16 out of 100,000 women and 3 out of 100,000 men annually
}}
'''Infiltrative Ophthalmopathy''' is a medical condition that affects the eyes, often associated with [[Graves' disease]]. It is characterized by inflammation and swelling of the eye muscles and tissues, leading to symptoms such as bulging eyes, double vision, and eye discomfort.
'''Infiltrative Ophthalmopathy''' is a medical condition that affects the eyes, often associated with [[Graves' disease]]. It is characterized by inflammation and swelling of the eye muscles and tissues, leading to symptoms such as bulging eyes, double vision, and eye discomfort.
== Symptoms ==
== Symptoms ==
Infiltrative ophthalmopathy can present with a variety of symptoms, including:
Infiltrative ophthalmopathy can present with a variety of symptoms, including:
* [[Proptosis]] or bulging eyes
* [[Proptosis]] or bulging eyes
* [[Diplopia]] or double vision
* [[Diplopia]] or double vision
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* Sensitivity to light
* Sensitivity to light
* Blurred vision
* Blurred vision
== Causes ==
== Causes ==
The exact cause of infiltrative ophthalmopathy is unknown, but it is often associated with [[Graves' disease]], an autoimmune disorder that affects the thyroid gland. In Graves' disease, the immune system mistakenly attacks the thyroid gland, causing it to produce too much thyroid hormone. This can lead to a variety of symptoms, including infiltrative ophthalmopathy.
The exact cause of infiltrative ophthalmopathy is unknown, but it is often associated with [[Graves' disease]], an autoimmune disorder that affects the thyroid gland. In Graves' disease, the immune system mistakenly attacks the thyroid gland, causing it to produce too much thyroid hormone. This can lead to a variety of symptoms, including infiltrative ophthalmopathy.
== Diagnosis ==
== Diagnosis ==
Diagnosis of infiltrative ophthalmopathy typically involves a thorough eye examination, including tests to measure the forward position of the eyes and the size of the eye muscles. Blood tests may also be done to check for the presence of thyroid antibodies, which can indicate Graves' disease.
Diagnosis of infiltrative ophthalmopathy typically involves a thorough eye examination, including tests to measure the forward position of the eyes and the size of the eye muscles. Blood tests may also be done to check for the presence of thyroid antibodies, which can indicate Graves' disease.
== Treatment ==
== Treatment ==
Treatment for infiltrative ophthalmopathy focuses on managing the symptoms and preventing further damage to the eyes. This may include:
Treatment for infiltrative ophthalmopathy focuses on managing the symptoms and preventing further damage to the eyes. This may include:
* [[Corticosteroids]] to reduce inflammation
* [[Corticosteroids]] to reduce inflammation
* [[Radiotherapy]] to shrink swollen tissues
* [[Radiotherapy]] to shrink swollen tissues
* [[Surgery]] to correct double vision or severe eye bulging
* [[Surgery]] to correct double vision or severe eye bulging
== See also ==
== See also ==
* [[Graves' disease]]
* [[Graves' disease]]
* [[Thyroid eye disease]]
* [[Thyroid eye disease]]
* [[Proptosis]]
* [[Proptosis]]
* [[Diplopia]]
* [[Diplopia]]
== References ==
== References ==
<references />
<references />
{{stub}}
{{stub}}
[[Category:Eye diseases]]
[[Category:Eye diseases]]
[[Category:Endocrine diseases]]
[[Category:Endocrine diseases]]
[[Category:Autoimmune diseases]]
[[Category:Autoimmune diseases]]
{{No image}}
{{No image}}

Latest revision as of 23:05, 3 April 2025


Infiltrative ophthalmopathy
Synonyms Thyroid eye disease, Graves' ophthalmopathy
Pronounce N/A
Specialty N/A
Symptoms Exophthalmos, diplopia, eye irritation, lid retraction, periorbital edema
Complications Corneal ulcer, vision loss
Onset Typically between ages 30 and 50
Duration Variable, can be chronic
Types N/A
Causes Autoimmune disorder, often associated with Graves' disease
Risks Smoking, female gender, radioiodine therapy
Diagnosis Clinical examination, imaging studies such as CT scan or MRI
Differential diagnosis Orbital cellulitis, orbital tumor, idiopathic orbital inflammation
Prevention N/A
Treatment Corticosteroids, orbital decompression surgery, radiotherapy, immunosuppressive therapy
Medication Prednisone, methimazole, propylthiouracil
Prognosis N/A
Frequency Affects approximately 16 out of 100,000 women and 3 out of 100,000 men annually
Deaths N/A


Infiltrative Ophthalmopathy is a medical condition that affects the eyes, often associated with Graves' disease. It is characterized by inflammation and swelling of the eye muscles and tissues, leading to symptoms such as bulging eyes, double vision, and eye discomfort.

Symptoms[edit]

Infiltrative ophthalmopathy can present with a variety of symptoms, including:

  • Proptosis or bulging eyes
  • Diplopia or double vision
  • Eye discomfort or pain
  • Redness and swelling of the eyes
  • Sensitivity to light
  • Blurred vision

Causes[edit]

The exact cause of infiltrative ophthalmopathy is unknown, but it is often associated with Graves' disease, an autoimmune disorder that affects the thyroid gland. In Graves' disease, the immune system mistakenly attacks the thyroid gland, causing it to produce too much thyroid hormone. This can lead to a variety of symptoms, including infiltrative ophthalmopathy.

Diagnosis[edit]

Diagnosis of infiltrative ophthalmopathy typically involves a thorough eye examination, including tests to measure the forward position of the eyes and the size of the eye muscles. Blood tests may also be done to check for the presence of thyroid antibodies, which can indicate Graves' disease.

Treatment[edit]

Treatment for infiltrative ophthalmopathy focuses on managing the symptoms and preventing further damage to the eyes. This may include:

See also[edit]

References[edit]

<references />

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