Hypergammaglobulinemia: Difference between revisions

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{{Infobox medical condition
| name            = Hypergammaglobulinemia
| synonyms        =
| specialty      = [[Immunology]]
| symptoms        = Elevated levels of [[gamma globulins]] in the blood
| complications  = [[Autoimmune diseases]], [[infections]]
| onset          = Varies depending on underlying cause
| duration        = Chronic
| causes          = [[Chronic infections]], [[autoimmune disorders]], [[liver disease]], [[monoclonal gammopathy]]
| risks          =
| diagnosis      = [[Blood test]] showing elevated [[immunoglobulins]]
| differential    = [[Monoclonal gammopathy of undetermined significance]], [[multiple myeloma]], [[chronic lymphocytic leukemia]]
| prevention      =
| treatment      = Address underlying cause, [[immunosuppressive therapy]]
| medication      = [[Corticosteroids]], [[immunosuppressants]]
| prognosis      = Depends on underlying condition
| frequency      = Common in certain populations with chronic conditions
}}
'''Hypergammaglobulinemia''' is a condition characterized by an excess of [[gamma globulins]] in the blood. Gamma globulins are a type of [[protein]] produced by the [[immune system]] to help fight infections. Hypergammaglobulinemia can be a sign of various underlying conditions, including chronic [[infections]], [[autoimmune diseases]], and certain types of [[cancer]].
'''Hypergammaglobulinemia''' is a condition characterized by an excess of [[gamma globulins]] in the blood. Gamma globulins are a type of [[protein]] produced by the [[immune system]] to help fight infections. Hypergammaglobulinemia can be a sign of various underlying conditions, including chronic [[infections]], [[autoimmune diseases]], and certain types of [[cancer]].
== Causes ==
== Causes ==
Hypergammaglobulinemia can be caused by a variety of conditions, including:
Hypergammaglobulinemia can be caused by a variety of conditions, including:
* Chronic infections, such as [[hepatitis]] or [[HIV]]
* Chronic infections, such as [[hepatitis]] or [[HIV]]
* Autoimmune diseases, such as [[rheumatoid arthritis]] or [[systemic lupus erythematosus]]
* Autoimmune diseases, such as [[rheumatoid arthritis]] or [[systemic lupus erythematosus]]
* Certain types of cancer, such as [[multiple myeloma]] or [[lymphoma]]
* Certain types of cancer, such as [[multiple myeloma]] or [[lymphoma]]
== Symptoms ==
== Symptoms ==
The symptoms of hypergammaglobulinemia can vary depending on the underlying cause. They may include:
The symptoms of hypergammaglobulinemia can vary depending on the underlying cause. They may include:
* Fatigue
* Fatigue
* Joint pain
* Joint pain
* Swollen [[lymph nodes]]
* Swollen [[lymph nodes]]
* Recurrent infections
* Recurrent infections
== Diagnosis ==
== Diagnosis ==
Hypergammaglobulinemia is typically diagnosed through a [[blood test]] that measures the levels of gamma globulins in the blood. Additional tests may be needed to determine the underlying cause.
Hypergammaglobulinemia is typically diagnosed through a [[blood test]] that measures the levels of gamma globulins in the blood. Additional tests may be needed to determine the underlying cause.
== Treatment ==
== Treatment ==
Treatment for hypergammaglobulinemia typically involves addressing the underlying cause. This may involve [[antibiotics]] for infections, [[immunosuppressive drugs]] for autoimmune diseases, or [[chemotherapy]] for cancer.
Treatment for hypergammaglobulinemia typically involves addressing the underlying cause. This may involve [[antibiotics]] for infections, [[immunosuppressive drugs]] for autoimmune diseases, or [[chemotherapy]] for cancer.
== See also ==
== See also ==
* [[Gamma globulin]]
* [[Gamma globulin]]
* [[Immunoglobulin]]
* [[Immunoglobulin]]
* [[Multiple myeloma]]
* [[Multiple myeloma]]
* [[Lymphoma]]
* [[Lymphoma]]
[[Category:Medical conditions]]
[[Category:Medical conditions]]
[[Category:Immunology]]
[[Category:Immunology]]
[[Category:Hematology]]
[[Category:Hematology]]
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Latest revision as of 02:14, 4 April 2025


Hypergammaglobulinemia
Synonyms
Pronounce N/A
Specialty Immunology
Symptoms Elevated levels of gamma globulins in the blood
Complications Autoimmune diseases, infections
Onset Varies depending on underlying cause
Duration Chronic
Types N/A
Causes Chronic infections, autoimmune disorders, liver disease, monoclonal gammopathy
Risks
Diagnosis Blood test showing elevated immunoglobulins
Differential diagnosis Monoclonal gammopathy of undetermined significance, multiple myeloma, chronic lymphocytic leukemia
Prevention
Treatment Address underlying cause, immunosuppressive therapy
Medication Corticosteroids, immunosuppressants
Prognosis Depends on underlying condition
Frequency Common in certain populations with chronic conditions
Deaths N/A


Hypergammaglobulinemia is a condition characterized by an excess of gamma globulins in the blood. Gamma globulins are a type of protein produced by the immune system to help fight infections. Hypergammaglobulinemia can be a sign of various underlying conditions, including chronic infections, autoimmune diseases, and certain types of cancer.

Causes[edit]

Hypergammaglobulinemia can be caused by a variety of conditions, including:

Symptoms[edit]

The symptoms of hypergammaglobulinemia can vary depending on the underlying cause. They may include:

  • Fatigue
  • Joint pain
  • Swollen lymph nodes
  • Recurrent infections

Diagnosis[edit]

Hypergammaglobulinemia is typically diagnosed through a blood test that measures the levels of gamma globulins in the blood. Additional tests may be needed to determine the underlying cause.

Treatment[edit]

Treatment for hypergammaglobulinemia typically involves addressing the underlying cause. This may involve antibiotics for infections, immunosuppressive drugs for autoimmune diseases, or chemotherapy for cancer.

See also[edit]

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