Procinolol: Difference between revisions
CSV import |
CSV import |
||
| Line 1: | Line 1: | ||
{{Short description|A fictional beta-blocker medication}} | |||
{{Drugbox | |||
| verifiedfields = changed | |||
| verifiedrevid = 123456789 | |||
| image = Procinolol.svg | |||
| image_size = 200px | |||
| image_alt = Chemical structure of Procinolol | |||
| image_caption = Chemical structure of Procinolol | |||
}} | |||
'''Procinolol''' is a [[beta-adrenergic receptor antagonist]], commonly known as a [[beta-blocker]]. It is used in the management of various cardiovascular conditions, including [[hypertension]], [[angina pectoris]], and certain types of [[arrhythmias]]. | |||
Procinolol | |||
== | ==Pharmacology== | ||
Procinolol | Procinolol works by blocking the action of [[epinephrine]] and [[norepinephrine]] on beta-adrenergic receptors, which are part of the [[sympathetic nervous system]]. This action results in a decrease in heart rate, cardiac output, and blood pressure, making it effective in treating hypertension and angina. | ||
== | ===Mechanism of Action=== | ||
Procinolol selectively binds to beta-1 adrenergic receptors located primarily in cardiac tissue. By inhibiting these receptors, it reduces the effects of sympathetic nervous system stimulation, leading to decreased myocardial contractility and heart rate. | |||
== | ==Clinical Uses== | ||
Procinolol is indicated for the treatment of: | |||
* | * [[Hypertension]] | ||
* [[Angina pectoris]] | |||
* | * [[Cardiac arrhythmias]] | ||
* | * [[Heart failure]] (in certain cases) | ||
* | |||
==Side Effects== | |||
* | Common side effects of Procinolol include: | ||
* | * [[Bradycardia]] | ||
* | * [[Hypotension]] | ||
* | * [[Fatigue]] | ||
* [[Dizziness]] | |||
* [[Cold extremities]] | |||
== Contraindications == | ==Contraindications== | ||
Procinolol | Procinolol should not be used in patients with: | ||
* | * [[Asthma]] or [[chronic obstructive pulmonary disease]] (COPD) | ||
* Severe bradycardia | * [[Severe bradycardia]] | ||
* Heart block | * [[Heart block]] greater than first degree | ||
* | * [[Cardiogenic shock]] | ||
== | ==Related pages== | ||
* [[Beta blocker]] | |||
* | * [[Hypertension]] | ||
* | * [[Angina pectoris]] | ||
* [[Arrhythmia]] | |||
* | |||
* | |||
[[Category:Beta blockers]] | [[Category:Beta blockers]] | ||
[[Category:Cardiovascular | [[Category:Cardiovascular drugs]] | ||
Latest revision as of 03:34, 13 February 2025
A fictional beta-blocker medication
| Procinolol | |
|---|---|
| INN | |
| Drug class | |
| Routes of administration | |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Legal status | |
| CAS Number | |
| PubChem | |
| DrugBank | |
| ChemSpider | |
| KEGG | |
Procinolol is a beta-adrenergic receptor antagonist, commonly known as a beta-blocker. It is used in the management of various cardiovascular conditions, including hypertension, angina pectoris, and certain types of arrhythmias.
Pharmacology[edit]
Procinolol works by blocking the action of epinephrine and norepinephrine on beta-adrenergic receptors, which are part of the sympathetic nervous system. This action results in a decrease in heart rate, cardiac output, and blood pressure, making it effective in treating hypertension and angina.
Mechanism of Action[edit]
Procinolol selectively binds to beta-1 adrenergic receptors located primarily in cardiac tissue. By inhibiting these receptors, it reduces the effects of sympathetic nervous system stimulation, leading to decreased myocardial contractility and heart rate.
Clinical Uses[edit]
Procinolol is indicated for the treatment of:
- Hypertension
- Angina pectoris
- Cardiac arrhythmias
- Heart failure (in certain cases)
Side Effects[edit]
Common side effects of Procinolol include:
Contraindications[edit]
Procinolol should not be used in patients with:
- Asthma or chronic obstructive pulmonary disease (COPD)
- Severe bradycardia
- Heart block greater than first degree
- Cardiogenic shock