TRPM3: Difference between revisions
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'''TRPM3''' is a | TRPM3 | ||
'''TRPM3''' (Transient Receptor Potential Cation Channel Subfamily M Member 3) is a protein that in humans is encoded by the '''TRPM3''' gene. This protein is part of the [[transient receptor potential channel]] family, which is involved in various physiological processes. | |||
== Function == | == Function == | ||
TRPM3 | TRPM3 channels are [[ion channel]]s that allow the passage of [[calcium]] and other cations into cells. They are activated by [[heat]], [[steroid hormones]], and other stimuli. TRPM3 is expressed in various tissues, including the [[brain]], [[kidney]], and [[pancreas]]. | ||
== Clinical | == Clinical Significance == | ||
Mutations in the | Mutations in the TRPM3 gene have been associated with [[disease]]s such as [[congenital cataracts]] and [[intellectual disability]]. TRPM3 is also being studied for its role in [[pain perception]] and [[inflammation]]. | ||
TRPM3 | |||
== Research == | == Research == | ||
Recent studies have shown that TRPM3 can be modulated by [[pharmacological agents]], making it a potential target for [[drug development]]. Researchers are investigating its role in [[neuropathic pain]] and [[metabolic disorders]]. | |||
[[ | |||
== See | == See Also == | ||
* [[ | * [[TRP channel]] | ||
* [[Ion channel]] | * [[Ion channel]] | ||
* [[Calcium signaling]] | * [[Calcium signaling]] | ||
== References == | == References == | ||
<references /> | <references/> | ||
== External Links == | |||
* [https://www.ncbi.nlm.nih.gov/gene/80036 TRPM3 Gene - NCBI] | |||
* [https://www.uniprot.org/uniprot/Q9HCF6 TRPM3 Protein - UniProt] | |||
{{Ion channels}} | |||
{{TRP channels}} | |||
[[Category:Ion channels]] | [[Category:Ion channels]] | ||
[[Category: | [[Category:TRP channels]] | ||
[[Category: | [[Category:Human proteins]] | ||
[[Category: | [[Category:Genes on human chromosome 9]] | ||
Latest revision as of 20:43, 30 December 2024
TRPM3
TRPM3 (Transient Receptor Potential Cation Channel Subfamily M Member 3) is a protein that in humans is encoded by the TRPM3 gene. This protein is part of the transient receptor potential channel family, which is involved in various physiological processes.
Function[edit]
TRPM3 channels are ion channels that allow the passage of calcium and other cations into cells. They are activated by heat, steroid hormones, and other stimuli. TRPM3 is expressed in various tissues, including the brain, kidney, and pancreas.
Clinical Significance[edit]
Mutations in the TRPM3 gene have been associated with diseases such as congenital cataracts and intellectual disability. TRPM3 is also being studied for its role in pain perception and inflammation.
Research[edit]
Recent studies have shown that TRPM3 can be modulated by pharmacological agents, making it a potential target for drug development. Researchers are investigating its role in neuropathic pain and metabolic disorders.
See Also[edit]
References[edit]
<references/>
External Links[edit]
