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'''Matrix (biology)'''


[[File:Extracellular matrix.svg|thumb|right|300px|Illustration of the major elements in extracellular matrix]]
{{Short description|Biological matrix overview}}
{{Use dmy dates|date=October 2023}}
{{Infobox anatomy
| Name        = Matrix (biology)
| Image        =
| Caption      =
| System      =
| Function    = Structural support
}}


The '''matrix''' in [[biology]] refers to the non-cellular component present within all tissues and organs, and primarily consists of [[water]], [[protein]]s, and [[polysaccharide]]s. It provides essential physical scaffolding for the cellular constituents and initiates crucial biochemical and biomechanical cues that are required for tissue morphogenesis, differentiation and homeostasis.
The '''matrix''' in [[biology]] refers to the material or tissue in [[animal]] or [[plant]] cells, in which more specialized structures are embedded. It is a complex and dynamic environment that provides structural and biochemical support to the surrounding cells.


== Composition ==
==Types of Biological Matrices==


The matrix is composed of two main classes of biomolecules: [[glycosaminoglycan]]s (GAGs) and [[fibrous protein]]s. GAGs are polysaccharides that trap water, providing the matrix with a gel-like texture. Fibrous proteins, on the other hand, provide structural support. These include [[collagen]], [[elastin]], [[fibronectin]], and [[laminin]].
===Extracellular Matrix===
The [[extracellular matrix]] (ECM) is a three-dimensional network of [[extracellular macromolecules]] such as [[collagen]], [[enzymes]], and [[glycoproteins]] that provide structural and biochemical support to surrounding cells. The ECM is involved in many important functions, including cell adhesion, cell-to-cell communication, and differentiation.


== Function ==
===Intracellular Matrix===
The [[intracellular matrix]] refers to the cytosol and the organelles within a cell. It is the site of many metabolic processes and provides a medium for the movement of ions, molecules, and organelles within the cell.


The matrix plays a crucial role in the following biological functions:
===Bone Matrix===
The [[bone matrix]] is the intercellular substance of bone tissue, consisting of collagen fibers, ground substance, and inorganic bone salts. It provides strength and rigidity to bones.


* '''Structural support:''' The matrix provides a scaffold for the cells, helping to maintain the physical structure of the tissue.
===Cartilage Matrix===
* '''Biochemical signaling:''' The matrix is involved in cell signaling, influencing cell growth, migration, and differentiation.
The [[cartilage matrix]] is composed of collagen fibers and proteoglycans, providing a smooth surface for joint movement and acting as a cushion between bones.
* '''Tissue repair:''' The matrix plays a key role in the repair and healing of tissues.


== Types of Matrix ==
==Functions of the Matrix==
The matrix plays a crucial role in:
* Providing structural support to tissues and organs.
* Facilitating cell adhesion and communication.
* Regulating cell growth, movement, and differentiation.
* Serving as a reservoir for growth factors and cytokines.


There are two main types of matrix in biology:
==Matrix in Disease==
Alterations in the matrix can lead to various [[diseases]] and [[disorders]]. For example, excessive deposition of ECM components can result in [[fibrosis]], while degradation of the matrix can lead to [[arthritis]] and other degenerative diseases.


* '''Extracellular matrix:''' This is the matrix found outside of cells, primarily in [[connective tissue]]s. It provides structural and biochemical support to the surrounding cells.
==See Also==
* '''Intracellular matrix:''' This is the matrix found inside cells, providing a scaffold for the cell's internal components.
* [[Tissue (biology)]]
* [[Cell (biology)]]
* [[Collagen]]
* [[Proteoglycan]]


== See also ==
==References==
{{Reflist}}


* [[Extracellular matrix]]
==External Links==
* [[Intracellular matrix]]
* [https://www.wikimd.com/wiki/Matrix_(biology) Matrix (biology) on WikiMD]
* [[Connective tissue]]
* [[Glycosaminoglycan]]
* [[Fibrous protein]]
 
== References ==
 
<references />
 
{{anatomy-stub}}


[[Category:Biology]]
[[Category:Biology]]
[[Category:Cell biology]]
[[Category:Cell biology]]
[[Category:Tissues]]
[[Category:Anatomy]]
[[Category:Anatomy]]

Latest revision as of 16:59, 29 December 2024


Biological matrix overview



General Information
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TA98
TA2
FMA
Details
System
Artery
Vein
Nerve
Lymphatic drainage
Precursor
Function Structural support
Identifiers
Clinical significance
Notes


The matrix in biology refers to the material or tissue in animal or plant cells, in which more specialized structures are embedded. It is a complex and dynamic environment that provides structural and biochemical support to the surrounding cells.

Types of Biological Matrices[edit]

Extracellular Matrix[edit]

The extracellular matrix (ECM) is a three-dimensional network of extracellular macromolecules such as collagen, enzymes, and glycoproteins that provide structural and biochemical support to surrounding cells. The ECM is involved in many important functions, including cell adhesion, cell-to-cell communication, and differentiation.

Intracellular Matrix[edit]

The intracellular matrix refers to the cytosol and the organelles within a cell. It is the site of many metabolic processes and provides a medium for the movement of ions, molecules, and organelles within the cell.

Bone Matrix[edit]

The bone matrix is the intercellular substance of bone tissue, consisting of collagen fibers, ground substance, and inorganic bone salts. It provides strength and rigidity to bones.

Cartilage Matrix[edit]

The cartilage matrix is composed of collagen fibers and proteoglycans, providing a smooth surface for joint movement and acting as a cushion between bones.

Functions of the Matrix[edit]

The matrix plays a crucial role in:

  • Providing structural support to tissues and organs.
  • Facilitating cell adhesion and communication.
  • Regulating cell growth, movement, and differentiation.
  • Serving as a reservoir for growth factors and cytokines.

Matrix in Disease[edit]

Alterations in the matrix can lead to various diseases and disorders. For example, excessive deposition of ECM components can result in fibrosis, while degradation of the matrix can lead to arthritis and other degenerative diseases.

See Also[edit]

References[edit]

<references group="" responsive="1"></references>


External Links[edit]