Leukemia cutis: Difference between revisions
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{{Infobox medical condition | |||
| name = Leukemia cutis | |||
| synonyms = | |||
| specialty = [[Dermatology]], [[Hematology]] | |||
| symptoms = [[Skin lesions]], [[nodules]], [[plaques]], [[papules]] | |||
| onset = | |||
| duration = | |||
| causes = [[Leukemia]] | |||
| risks = | |||
| diagnosis = [[Skin biopsy]], [[Histopathology]] | |||
| differential = [[Lymphoma cutis]], [[Sweet's syndrome]], [[Sarcoidosis]] | |||
| treatment = [[Chemotherapy]], [[Radiation therapy]], [[Targeted therapy]] | |||
| prognosis = | |||
| frequency = Rare | |||
}} | |||
'''Leukemia cutis''' refers to the infiltration of the [[skin]] by malignant [[leukocytes]] or their precursors, resulting in clinically identifiable cutaneous lesions. It is a specific type of [[neoplastic]] infiltration of the skin in patients with [[leukemia]]. | '''Leukemia cutis''' refers to the infiltration of the [[skin]] by malignant [[leukocytes]] or their precursors, resulting in clinically identifiable cutaneous lesions. It is a specific type of [[neoplastic]] infiltration of the skin in patients with [[leukemia]]. | ||
==Etiology== | ==Etiology== | ||
Leukemia cutis often occurs in patients with systemic leukemia, particularly those with [[acute myeloid leukemia]] (AML). However, it can also occur with other types of leukemia, including [[chronic lymphocytic leukemia]] (CLL), [[acute lymphoblastic leukemia]] (ALL), and [[chronic myeloid leukemia]] (CML). | Leukemia cutis often occurs in patients with systemic leukemia, particularly those with [[acute myeloid leukemia]] (AML). However, it can also occur with other types of leukemia, including [[chronic lymphocytic leukemia]] (CLL), [[acute lymphoblastic leukemia]] (ALL), and [[chronic myeloid leukemia]] (CML). | ||
==Clinical Presentation== | ==Clinical Presentation== | ||
The clinical presentation of leukemia cutis can vary widely. Lesions may appear as papules, nodules, plaques, or ulcers and can be found anywhere on the body. The color of the lesions can range from pink to purple to brown. In some cases, the lesions may be asymptomatic, while in others they may cause itching or pain. | The clinical presentation of leukemia cutis can vary widely. Lesions may appear as papules, nodules, plaques, or ulcers and can be found anywhere on the body. The color of the lesions can range from pink to purple to brown. In some cases, the lesions may be asymptomatic, while in others they may cause itching or pain. | ||
==Diagnosis== | ==Diagnosis== | ||
The diagnosis of leukemia cutis is typically made through a combination of clinical examination, [[histopathology]], and [[immunohistochemistry]]. A skin biopsy is often performed to confirm the diagnosis. In some cases, additional tests such as [[flow cytometry]] may be used to further characterize the leukemic cells. | The diagnosis of leukemia cutis is typically made through a combination of clinical examination, [[histopathology]], and [[immunohistochemistry]]. A skin biopsy is often performed to confirm the diagnosis. In some cases, additional tests such as [[flow cytometry]] may be used to further characterize the leukemic cells. | ||
==Treatment== | ==Treatment== | ||
The treatment of leukemia cutis is primarily aimed at treating the underlying leukemia. This typically involves [[chemotherapy]], and in some cases, [[radiation therapy]] or [[stem cell transplantation]] may be used. Topical treatments, such as [[corticosteroids]], may also be used to manage skin symptoms. | The treatment of leukemia cutis is primarily aimed at treating the underlying leukemia. This typically involves [[chemotherapy]], and in some cases, [[radiation therapy]] or [[stem cell transplantation]] may be used. Topical treatments, such as [[corticosteroids]], may also be used to manage skin symptoms. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis of leukemia cutis is generally poor, as it often indicates advanced or aggressive leukemia. However, the prognosis can vary depending on the type of leukemia and the patient's overall health. | The prognosis of leukemia cutis is generally poor, as it often indicates advanced or aggressive leukemia. However, the prognosis can vary depending on the type of leukemia and the patient's overall health. | ||
==See Also== | ==See Also== | ||
* [[Leukemia]] | * [[Leukemia]] | ||
* [[Cutaneous T-cell lymphoma]] | * [[Cutaneous T-cell lymphoma]] | ||
* [[Skin cancer]] | * [[Skin cancer]] | ||
[[Category:Leukemia]] | [[Category:Leukemia]] | ||
[[Category:Dermatologic terminology]] | [[Category:Dermatologic terminology]] | ||
| Line 27: | Line 36: | ||
{{Dermatology-stub}} | {{Dermatology-stub}} | ||
{{Oncology-stub}} | {{Oncology-stub}} | ||
{{No image}} | |||
Latest revision as of 00:59, 4 April 2025
| Leukemia cutis | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | Dermatology, Hematology |
| Symptoms | Skin lesions, nodules, plaques, papules |
| Complications | N/A |
| Onset | |
| Duration | |
| Types | N/A |
| Causes | Leukemia |
| Risks | |
| Diagnosis | Skin biopsy, Histopathology |
| Differential diagnosis | Lymphoma cutis, Sweet's syndrome, Sarcoidosis |
| Prevention | N/A |
| Treatment | Chemotherapy, Radiation therapy, Targeted therapy |
| Medication | N/A |
| Prognosis | |
| Frequency | Rare |
| Deaths | N/A |
Leukemia cutis refers to the infiltration of the skin by malignant leukocytes or their precursors, resulting in clinically identifiable cutaneous lesions. It is a specific type of neoplastic infiltration of the skin in patients with leukemia.
Etiology[edit]
Leukemia cutis often occurs in patients with systemic leukemia, particularly those with acute myeloid leukemia (AML). However, it can also occur with other types of leukemia, including chronic lymphocytic leukemia (CLL), acute lymphoblastic leukemia (ALL), and chronic myeloid leukemia (CML).
Clinical Presentation[edit]
The clinical presentation of leukemia cutis can vary widely. Lesions may appear as papules, nodules, plaques, or ulcers and can be found anywhere on the body. The color of the lesions can range from pink to purple to brown. In some cases, the lesions may be asymptomatic, while in others they may cause itching or pain.
Diagnosis[edit]
The diagnosis of leukemia cutis is typically made through a combination of clinical examination, histopathology, and immunohistochemistry. A skin biopsy is often performed to confirm the diagnosis. In some cases, additional tests such as flow cytometry may be used to further characterize the leukemic cells.
Treatment[edit]
The treatment of leukemia cutis is primarily aimed at treating the underlying leukemia. This typically involves chemotherapy, and in some cases, radiation therapy or stem cell transplantation may be used. Topical treatments, such as corticosteroids, may also be used to manage skin symptoms.
Prognosis[edit]
The prognosis of leukemia cutis is generally poor, as it often indicates advanced or aggressive leukemia. However, the prognosis can vary depending on the type of leukemia and the patient's overall health.
See Also[edit]
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