Sertoli cell tumour: Difference between revisions
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{{SI}} | |||
{{Infobox medical condition | |||
| name = Sertoli cell tumour | |||
| image = [[File:Sertoli_cell_tumour_high_mag.jpg|250px]] | |||
| caption = Micrograph of a Sertoli cell tumour | |||
| field = [[Oncology]] | |||
| synonyms = Sertoli cell tumor | |||
| symptoms = [[Testicular mass]], [[gynecomastia]], [[infertility]] | |||
| complications = [[Metastasis]] | |||
| onset = Any age, but most common in adults | |||
| duration = Variable | |||
| types = [[Benign]], [[Malignant]] | |||
| causes = Unknown | |||
| risks = [[Genetic syndromes]] such as [[Peutz-Jeghers syndrome]], [[Carney complex]] | |||
| diagnosis = [[Histopathology]], [[Imaging studies]] | |||
| differential = [[Leydig cell tumour]], [[Germ cell tumour]], [[Testicular cancer]] | |||
| prevention = None | |||
| treatment = [[Surgery]], [[Radiation therapy]], [[Chemotherapy]] | |||
| prognosis = Generally good for benign tumors, variable for malignant | |||
| frequency = Rare | |||
}} | |||
[[File:Sertoli cell tumour low mag.jpg|Sertoli cell tumour low magnification|thumb|left]] | |||
[[File:Leydig cell tumour2.jpg|Leydig cell tumour|thumb|left]] | |||
[[File:Leydig cell tumour3.jpg|Leydig cell tumour|thumb|left]] | |||
'''Sertoli cell tumour''' is a type of [[testicular cancer]] that originates from the [[Sertoli cells]] in the [[testis]]. These cells are part of the [[seminiferous tubules]] and play a crucial role in [[spermatogenesis]], the process of sperm production. | '''Sertoli cell tumour''' is a type of [[testicular cancer]] that originates from the [[Sertoli cells]] in the [[testis]]. These cells are part of the [[seminiferous tubules]] and play a crucial role in [[spermatogenesis]], the process of sperm production. | ||
== Introduction == | |||
== | |||
Sertoli cell tumours are rare and account for less than 1% of all testicular cancers. They are usually benign, but in rare cases, they can be malignant. The tumours are often discovered during a physical examination or through imaging tests. Symptoms may include a lump in the testicle, testicular pain or discomfort, and in some cases, gynecomastia (enlargement of male breasts) due to hormonal changes. | Sertoli cell tumours are rare and account for less than 1% of all testicular cancers. They are usually benign, but in rare cases, they can be malignant. The tumours are often discovered during a physical examination or through imaging tests. Symptoms may include a lump in the testicle, testicular pain or discomfort, and in some cases, gynecomastia (enlargement of male breasts) due to hormonal changes. | ||
==Diagnosis== | ==Diagnosis== | ||
The diagnosis of a Sertoli cell tumour is typically confirmed through a [[biopsy]], where a small sample of the tumour is removed and examined under a microscope. [[Immunohistochemistry]] is often used to differentiate Sertoli cell tumours from other types of testicular tumours. | The diagnosis of a Sertoli cell tumour is typically confirmed through a [[biopsy]], where a small sample of the tumour is removed and examined under a microscope. [[Immunohistochemistry]] is often used to differentiate Sertoli cell tumours from other types of testicular tumours. | ||
==Treatment== | ==Treatment== | ||
The primary treatment for Sertoli cell tumours is surgical removal of the tumour, known as [[orchiectomy]]. In some cases, additional treatments such as [[radiation therapy]] or [[chemotherapy]] may be recommended, particularly if the tumour is malignant or if it has spread to other parts of the body. | The primary treatment for Sertoli cell tumours is surgical removal of the tumour, known as [[orchiectomy]]. In some cases, additional treatments such as [[radiation therapy]] or [[chemotherapy]] may be recommended, particularly if the tumour is malignant or if it has spread to other parts of the body. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for individuals with Sertoli cell tumours is generally good, particularly if the tumour is detected early and is benign. However, malignant tumours or those that have spread can be more challenging to treat and may have a poorer prognosis. | The prognosis for individuals with Sertoli cell tumours is generally good, particularly if the tumour is detected early and is benign. However, malignant tumours or those that have spread can be more challenging to treat and may have a poorer prognosis. | ||
==See also== | ==See also== | ||
* [[Testicular cancer]] | * [[Testicular cancer]] | ||
| Line 18: | Line 37: | ||
* [[Spermatogenesis]] | * [[Spermatogenesis]] | ||
* [[Orchiectomy]] | * [[Orchiectomy]] | ||
[[Category:Testicular cancer]] | [[Category:Testicular cancer]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Urological diseases]] | [[Category:Urological diseases]] | ||
{{Medicine-stub}} | {{Medicine-stub}} | ||
Latest revision as of 08:55, 13 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics
| Sertoli cell tumour | |
|---|---|
| File:Sertoli cell tumour high mag.jpg | |
| Synonyms | Sertoli cell tumor |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Testicular mass, gynecomastia, infertility |
| Complications | Metastasis |
| Onset | Any age, but most common in adults |
| Duration | Variable |
| Types | Benign, Malignant |
| Causes | Unknown |
| Risks | Genetic syndromes such as Peutz-Jeghers syndrome, Carney complex |
| Diagnosis | Histopathology, Imaging studies |
| Differential diagnosis | Leydig cell tumour, Germ cell tumour, Testicular cancer |
| Prevention | None |
| Treatment | Surgery, Radiation therapy, Chemotherapy |
| Medication | N/A |
| Prognosis | Generally good for benign tumors, variable for malignant |
| Frequency | Rare |
| Deaths | N/A |
Sertoli cell tumour is a type of testicular cancer that originates from the Sertoli cells in the testis. These cells are part of the seminiferous tubules and play a crucial role in spermatogenesis, the process of sperm production.
Introduction[edit]
Sertoli cell tumours are rare and account for less than 1% of all testicular cancers. They are usually benign, but in rare cases, they can be malignant. The tumours are often discovered during a physical examination or through imaging tests. Symptoms may include a lump in the testicle, testicular pain or discomfort, and in some cases, gynecomastia (enlargement of male breasts) due to hormonal changes.
Diagnosis[edit]
The diagnosis of a Sertoli cell tumour is typically confirmed through a biopsy, where a small sample of the tumour is removed and examined under a microscope. Immunohistochemistry is often used to differentiate Sertoli cell tumours from other types of testicular tumours.
Treatment[edit]
The primary treatment for Sertoli cell tumours is surgical removal of the tumour, known as orchiectomy. In some cases, additional treatments such as radiation therapy or chemotherapy may be recommended, particularly if the tumour is malignant or if it has spread to other parts of the body.
Prognosis[edit]
The prognosis for individuals with Sertoli cell tumours is generally good, particularly if the tumour is detected early and is benign. However, malignant tumours or those that have spread can be more challenging to treat and may have a poorer prognosis.
See also[edit]
