Lonazolac: Difference between revisions

Lonazolac
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Latest revision as of 03:30, 13 February 2025

A non-steroidal anti-inflammatory drug

Lonazolac is a non-steroidal anti-inflammatory drug (NSAID) used primarily for its analgesic and anti-inflammatory properties. It is part of a class of medications that work by inhibiting the cyclooxygenase (COX) enzymes, which play a key role in the inflammatory process.

Pharmacology[edit]

Lonazolac functions by inhibiting the activity of the cyclooxygenase enzymes, specifically COX-1 and COX-2. These enzymes are responsible for the conversion of arachidonic acid into prostaglandins, which are mediators of inflammation and pain. By reducing the production of prostaglandins, Lonazolac helps to alleviate symptoms associated with inflammation such as pain, swelling, and fever.

Medical uses[edit]

Lonazolac is used in the management of various conditions characterized by pain and inflammation. These include:

Side effects[edit]

Like other NSAIDs, Lonazolac can cause a range of side effects. Common side effects include:

More serious side effects may include:

Mechanism of action[edit]

Lonazolac exerts its effects by non-selectively inhibiting the COX enzymes. This inhibition leads to a decrease in the synthesis of prostaglandins, which are compounds involved in the mediation of inflammation and pain. The reduction in prostaglandin levels results in decreased inflammation and pain relief.

Chemical properties[edit]

Lonazolac is a chemical compound with a specific structure that allows it to interact with the COX enzymes. Its chemical structure is characterized by a specific arrangement of atoms that confer its pharmacological activity.

Related pages[edit]

@@ Line 1: / Line 1: @@
-'''Lonazolac''' is a [[nonsteroidal anti-inflammatory drug]] (NSAID) that was developed for the treatment of [[rheumatoid arthritis]]. It is a [[pyrazolone]] derivative, and it works by inhibiting the production of [[prostaglandins]], which are chemicals that cause inflammation and pain in the body.
+{{Short description|A non-steroidal anti-inflammatory drug}}
+{{Drugbox
+| verifiedfields = changed
+| verifiedrevid = 477002123
+| image = lonazolac.png
+| image_size = 200px
+| image_alt = Chemical structure of Lonazolac
+| image_caption = Chemical structure of Lonazolac
+}}
+'''Lonazolac''' is a [[non-steroidal anti-inflammatory drug]] (NSAID) used primarily for its analgesic and anti-inflammatory properties. It is part of a class of medications that work by inhibiting the [[cyclooxygenase]] (COX) enzymes, which play a key role in the inflammatory process.
 ==Pharmacology==
-Lonazolac is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins. Prostaglandins are chemicals that are produced by the body and cause inflammation and pain. By inhibiting the production of these chemicals, lonazolac can help to reduce inflammation and pain.
+Lonazolac functions by inhibiting the activity of the cyclooxygenase enzymes, specifically COX-1 and COX-2. These enzymes are responsible for the conversion of [[arachidonic acid]] into [[prostaglandins]], which are mediators of inflammation and pain. By reducing the production of prostaglandins, Lonazolac helps to alleviate symptoms associated with inflammation such as pain, swelling, and fever.
-==Clinical use==
+==Medical uses==
-Lonazolac was developed for the treatment of rheumatoid arthritis. Rheumatoid arthritis is a chronic inflammatory disorder that can affect more than just your joints. In some people, the condition can damage a wide variety of body systems, including the skin, eyes, lungs, heart and blood vessels.
+Lonazolac is used in the management of various conditions characterized by pain and inflammation. These include:
+* [[Osteoarthritis]]
+* [[Rheumatoid arthritis]]
+* [[Ankylosing spondylitis]]
+* Acute musculoskeletal pain
 ==Side effects==
-Like all NSAIDs, lonazolac can cause side effects. These can include stomach upset, nausea, vomiting, heartburn, headache, diarrhea, constipation, drowsiness, and dizziness. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
+Like other NSAIDs, Lonazolac can cause a range of side effects. Common side effects include:
+* [[Gastrointestinal]] discomfort
+* [[Nausea]]
+* [[Dizziness]]
+* [[Headache]]
+More serious side effects may include:
+* [[Gastrointestinal bleeding]]
+* [[Renal impairment]]
+* [[Cardiovascular events]]
-==See also==
+==Mechanism of action==
-* [[Nonsteroidal anti-inflammatory drug]]
+[[File:lonazolac.png|thumb|right|Chemical structure of Lonazolac]]
-* [[Rheumatoid arthritis]]
+Lonazolac exerts its effects by non-selectively inhibiting the COX enzymes. This inhibition leads to a decrease in the synthesis of prostaglandins, which are compounds involved in the mediation of inflammation and pain. The reduction in prostaglandin levels results in decreased inflammation and pain relief.
+==Chemical properties==
+Lonazolac is a chemical compound with a specific structure that allows it to interact with the COX enzymes. Its chemical structure is characterized by a specific arrangement of atoms that confer its pharmacological activity.
+==Related pages==
+* [[Non-steroidal anti-inflammatory drug]]
+* [[Cyclooxygenase]]
 * [[Prostaglandin]]
-[[Category:Nonsteroidal anti-inflammatory drugs]]
+[[Category:Non-steroidal anti-inflammatory drugs]]
-[[Category:Pyrazolones]]
-[[Category:Rheumatoid arthritis]]
-{{stub}}