Gallbladder cancer: Difference between revisions
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'''Gallbladder cancer''' is a rare type of [[cancer]] that begins in the [[gallbladder]], a small, pear-shaped organ on the right side of the abdomen, beneath the [[liver]]. The gallbladder stores [[bile]], a digestive fluid produced by the liver. | {{SI}} | ||
{{Infobox medical condition | |||
| name = Gallbladder cancer | |||
| image = [[File:Illu_pancrease.svg|alt=Diagram of the pancreas and surrounding organs]] | |||
| caption = Diagram showing the location of the gallbladder (not directly shown in this image, but located near the liver and pancreas) | |||
| field = [[Oncology]] | |||
| symptoms = [[Abdominal pain]], [[jaundice]], [[nausea]], [[vomiting]], [[weight loss]] | |||
| complications = [[Metastasis]], [[biliary obstruction]] | |||
| onset = Typically in older adults | |||
| duration = Variable | |||
| types = [[Adenocarcinoma]], [[squamous cell carcinoma]], [[adenosquamous carcinoma]] | |||
| causes = [[Cholelithiasis]], [[chronic inflammation]], [[genetic mutations]] | |||
| risks = [[Gallstones]], [[chronic cholecystitis]], [[porcelain gallbladder]], [[primary sclerosing cholangitis]], [[obesity]], [[female gender]], [[age]] | |||
| diagnosis = [[Ultrasound]], [[CT scan]], [[MRI]], [[biopsy]] | |||
| differential = [[Cholecystitis]], [[cholangiocarcinoma]], [[hepatocellular carcinoma]] | |||
| prevention = [[Cholecystectomy]] in high-risk individuals | |||
| treatment = [[Surgery]], [[chemotherapy]], [[radiation therapy]] | |||
| prognosis = Generally poor, depends on stage at diagnosis | |||
| frequency = Rare | |||
}} | |||
[[File:Gallbladder_adenocarcinoma_(3)_lymphatic_invasion_histopathology.jpg|Histopathology of gallbladder adenocarcinoma with lymphatic invasion|thumb|left]] | |||
[[File:Gallbladder_adenocarcinoma_(1)_histopathology.jpg|Histopathology of gallbladder adenocarcinoma|thumb]] | |||
[[File:Gallbladder_adenocarcinoma_(2)_histopathology.jpg|Histopathology of gallbladder adenocarcinoma|thumb|left]] | |||
'''Gallbladder cancer''' is a rare type of [[cancer]] that begins in the [[gallbladder]], a small, pear-shaped organ on the right side of the abdomen, beneath the [[liver]]. The gallbladder stores [[bile]], a | |||
digestive fluid produced by the liver. | |||
==Symptoms== | ==Symptoms== | ||
Gallbladder cancer is difficult to diagnose because it often causes no specific signs or symptoms. Also, the relatively hidden nature of the gallbladder makes it easier for gallbladder cancer to grow without being detected. | Gallbladder cancer is difficult to diagnose because it often causes no specific signs or symptoms. Also, the relatively hidden nature of the gallbladder makes it easier for gallbladder cancer to grow without being detected. | ||
When gallbladder cancer symptoms do occur, they may include: | When gallbladder cancer symptoms do occur, they may include: | ||
* [[Jaundice]] | * [[Jaundice]] | ||
| Line 10: | Line 32: | ||
* Bloating | * Bloating | ||
* Fever | * Fever | ||
==Causes== | ==Causes== | ||
It's not clear what causes gallbladder cancer. Doctors know that gallbladder cancer forms when healthy gallbladder cells develop changes (mutations) in their DNA. These mutations cause cells to grow out of control and to continue living when other cells would normally die. The accumulating cells form a tumor that can grow beyond the gallbladder and spread to other areas of the body. | It's not clear what causes gallbladder cancer. Doctors know that gallbladder cancer forms when healthy gallbladder cells develop changes (mutations) in their DNA. These mutations cause cells to grow out of control and to continue living when other cells would normally die. The accumulating cells form a tumor that can grow beyond the gallbladder and spread to other areas of the body. | ||
==Risk factors== | ==Risk factors== | ||
Factors that can increase the risk of gallbladder cancer include: | Factors that can increase the risk of gallbladder cancer include: | ||
| Line 21: | Line 41: | ||
* Smoking | * Smoking | ||
* Your weight | * Your weight | ||
==Diagnosis== | ==Diagnosis== | ||
Tests and procedures used to diagnose gallbladder cancer include: | Tests and procedures used to diagnose gallbladder cancer include: | ||
| Line 27: | Line 46: | ||
* Procedures to create pictures of the gallbladder | * Procedures to create pictures of the gallbladder | ||
* Exploratory surgery | * Exploratory surgery | ||
==Treatment== | ==Treatment== | ||
Treatment options for gallbladder cancer include surgery, radiation therapy and chemotherapy. | Treatment options for gallbladder cancer include surgery, radiation therapy and chemotherapy. | ||
==See also== | ==See also== | ||
* [[Cancer]] | * [[Cancer]] | ||
* [[Gallstones]] | * [[Gallstones]] | ||
* [[Jaundice]] | * [[Jaundice]] | ||
[[Category:Medical conditions]] | [[Category:Medical conditions]] | ||
[[Category:Cancer]] | [[Category:Cancer]] | ||
[[Category:Gastrointestinal diseases]] | [[Category:Gastrointestinal diseases]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 23:52, 9 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics
| Gallbladder cancer | |
|---|---|
| Diagram of the pancreas and surrounding organs | |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Abdominal pain, jaundice, nausea, vomiting, weight loss |
| Complications | Metastasis, biliary obstruction |
| Onset | Typically in older adults |
| Duration | Variable |
| Types | Adenocarcinoma, squamous cell carcinoma, adenosquamous carcinoma |
| Causes | Cholelithiasis, chronic inflammation, genetic mutations |
| Risks | Gallstones, chronic cholecystitis, porcelain gallbladder, primary sclerosing cholangitis, obesity, female gender, age |
| Diagnosis | Ultrasound, CT scan, MRI, biopsy |
| Differential diagnosis | Cholecystitis, cholangiocarcinoma, hepatocellular carcinoma |
| Prevention | Cholecystectomy in high-risk individuals |
| Treatment | Surgery, chemotherapy, radiation therapy |
| Medication | N/A |
| Prognosis | Generally poor, depends on stage at diagnosis |
| Frequency | Rare |
| Deaths | N/A |
Gallbladder cancer is a rare type of cancer that begins in the gallbladder, a small, pear-shaped organ on the right side of the abdomen, beneath the liver. The gallbladder stores bile, a digestive fluid produced by the liver.
Symptoms[edit]
Gallbladder cancer is difficult to diagnose because it often causes no specific signs or symptoms. Also, the relatively hidden nature of the gallbladder makes it easier for gallbladder cancer to grow without being detected. When gallbladder cancer symptoms do occur, they may include:
- Jaundice
- Abdominal pain, particularly in the upper right portion of the abdomen
- Nausea and vomiting
- Bloating
- Fever
Causes[edit]
It's not clear what causes gallbladder cancer. Doctors know that gallbladder cancer forms when healthy gallbladder cells develop changes (mutations) in their DNA. These mutations cause cells to grow out of control and to continue living when other cells would normally die. The accumulating cells form a tumor that can grow beyond the gallbladder and spread to other areas of the body.
Risk factors[edit]
Factors that can increase the risk of gallbladder cancer include:
- Your age
- A history of gallstones
- Your sex
- Smoking
- Your weight
Diagnosis[edit]
Tests and procedures used to diagnose gallbladder cancer include:
- Blood tests
- Procedures to create pictures of the gallbladder
- Exploratory surgery
Treatment[edit]
Treatment options for gallbladder cancer include surgery, radiation therapy and chemotherapy.
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_histopathology.jpg){kind=link}
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