Leukocoria: Difference between revisions

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{{SI}}
{{Infobox medical condition
| name            = Leukocoria
| image          = [[File:Rb_whiteeye.PNG|left|thumb|Leukocoria in a child with retinoblastoma]]
| caption        = Leukocoria in a child with [[retinoblastoma]]
| field          = [[Ophthalmology]]
| symptoms        = Abnormal white reflection from the [[retina]]
| complications  = [[Blindness]], [[retinal detachment]]
| onset          = Can be present at birth or develop later
| duration        = Varies depending on underlying cause
| causes          = [[Retinoblastoma]], [[congenital cataract]], [[Coats' disease]], [[persistent fetal vasculature]], [[retinopathy of prematurity]]
| risks          = Family history of [[retinoblastoma]]
| diagnosis      = [[Ophthalmoscopy]], [[ultrasound]], [[CT scan]], [[MRI]]
| differential    = [[Cataract]], [[retinal detachment]], [[vitreous hemorrhage]]
| treatment      = Depends on underlying cause; may include [[surgery]], [[chemotherapy]], [[radiation therapy]]
| prognosis      = Varies; early detection and treatment improve outcomes
| frequency      = Rare
}}
[[File:Fundus_retinoblastoma.jpg|Retinoblastoma|thumb|left]]
'''Leukocoria''' (also known as '''white pupillary reflex''') is an abnormal white reflection from the retina of the eye. It is a medical sign for a number of conditions, primarily those affecting the retina or cornea, and is often detected in flash photography.
'''Leukocoria''' (also known as '''white pupillary reflex''') is an abnormal white reflection from the retina of the eye. It is a medical sign for a number of conditions, primarily those affecting the retina or cornea, and is often detected in flash photography.
== Causes ==
== Causes ==
Leukocoria can be caused by a number of conditions, including:
Leukocoria can be caused by a number of conditions, including:
* [[Retinoblastoma]]: A rare type of eye cancer that usually develops in early childhood, typically before the age of 5.
* [[Retinoblastoma]]: A rare type of eye cancer that usually develops in early childhood, typically before the age of 5.
* [[Coats' disease]]: A rare condition characterized by abnormal development of the blood vessels in the retina.
* [[Coats' disease]]: A rare condition characterized by abnormal development of the blood vessels in the retina.
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* [[Cataract]]: A clouding of the lens in the eye that affects vision.
* [[Cataract]]: A clouding of the lens in the eye that affects vision.
* [[Retinopathy of prematurity]] (ROP): A potentially blinding eye disorder that primarily affects premature infants.
* [[Retinopathy of prematurity]] (ROP): A potentially blinding eye disorder that primarily affects premature infants.
== Diagnosis ==
== Diagnosis ==
Diagnosis of leukocoria is typically made through a comprehensive eye examination. This may include:
Diagnosis of leukocoria is typically made through a comprehensive eye examination. This may include:
* [[Visual acuity test]]: This test measures how well the patient sees at various distances.
* [[Visual acuity test]]: This test measures how well the patient sees at various distances.
* [[Dilated eye exam]]: Drops are placed in the eyes to widen, or dilate, the pupils, allowing the doctor to examine the retina and optic nerve.
* [[Dilated eye exam]]: Drops are placed in the eyes to widen, or dilate, the pupils, allowing the doctor to examine the retina and optic nerve.
* [[Tonometry]]: An instrument measures the pressure inside the eye to check for glaucoma.
* [[Tonometry]]: An instrument measures the pressure inside the eye to check for glaucoma.
== Treatment ==
== Treatment ==
Treatment for leukocoria depends on the underlying cause and may include surgery, chemotherapy, laser therapy, or cryotherapy.
Treatment for leukocoria depends on the underlying cause and may include surgery, chemotherapy, laser therapy, or cryotherapy.
== See also ==
== See also ==
* [[Eye examination]]
* [[Eye examination]]
* [[Pediatric ophthalmology]]
* [[Pediatric ophthalmology]]
* [[Retinal diseases]]
* [[Retinal diseases]]
== References ==
== References ==
<references />
<references />
{{stub}}
{{stub}}
[[Category:Eye diseases]]
[[Category:Eye diseases]]
[[Category:Medical signs]]
[[Category:Medical signs]]
[[Category:Pediatric disorders]]
[[Category:Pediatric disorders]]

Latest revision as of 04:02, 9 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Leukocoria
Leukocoria in a child with retinoblastoma
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Abnormal white reflection from the retina
Complications Blindness, retinal detachment
Onset Can be present at birth or develop later
Duration Varies depending on underlying cause
Types N/A
Causes Retinoblastoma, congenital cataract, Coats' disease, persistent fetal vasculature, retinopathy of prematurity
Risks Family history of retinoblastoma
Diagnosis Ophthalmoscopy, ultrasound, CT scan, MRI
Differential diagnosis Cataract, retinal detachment, vitreous hemorrhage
Prevention N/A
Treatment Depends on underlying cause; may include surgery, chemotherapy, radiation therapy
Medication N/A
Prognosis Varies; early detection and treatment improve outcomes
Frequency Rare
Deaths N/A


Retinoblastoma

Leukocoria (also known as white pupillary reflex) is an abnormal white reflection from the retina of the eye. It is a medical sign for a number of conditions, primarily those affecting the retina or cornea, and is often detected in flash photography.

Causes[edit]

Leukocoria can be caused by a number of conditions, including:

  • Retinoblastoma: A rare type of eye cancer that usually develops in early childhood, typically before the age of 5.
  • Coats' disease: A rare condition characterized by abnormal development of the blood vessels in the retina.
  • Persistent hyperplastic primary vitreous (PHPV): A rare condition in which the blood vessels and fibrous tissue behind the lens of the eye do not regress normally during fetal development.
  • Cataract: A clouding of the lens in the eye that affects vision.
  • Retinopathy of prematurity (ROP): A potentially blinding eye disorder that primarily affects premature infants.

Diagnosis[edit]

Diagnosis of leukocoria is typically made through a comprehensive eye examination. This may include:

  • Visual acuity test: This test measures how well the patient sees at various distances.
  • Dilated eye exam: Drops are placed in the eyes to widen, or dilate, the pupils, allowing the doctor to examine the retina and optic nerve.
  • Tonometry: An instrument measures the pressure inside the eye to check for glaucoma.

Treatment[edit]

Treatment for leukocoria depends on the underlying cause and may include surgery, chemotherapy, laser therapy, or cryotherapy.

See also[edit]

References[edit]

<references />

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