Salicylate sensitivity: Difference between revisions

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[[File:Salicylic-acid-skeletal.svg|thumb|Salicylic-acid-skeletal.svg]] '''Salicylate sensitivity''' is a condition in which individuals experience adverse reactions to [[salicylates]], a group of chemicals found naturally in many plants and used in various medications, preservatives, and flavorings. Salicylates are present in foods, beverages, and personal care products, and they are also a key ingredient in [[aspirin]] and other non-steroidal anti-inflammatory drugs ([[NSAIDs]]).
{{SI}}
 
{{Infobox medical condition
| name                    = Salicylate sensitivity
| image                  = [[File:Salicylic-acid-skeletal.svg|150px]]
| caption                = Skeletal formula of [[salicylic acid]], a common salicylate
| field                  = [[Allergy and immunology]]
| symptoms                = [[Asthma]], [[rhinitis]], [[urticaria]], [[angioedema]], [[abdominal pain]], [[diarrhea]]
| onset                  = Variable, often within hours of exposure
| duration                = Variable, symptoms may persist as long as exposure continues
| causes                  = [[Salicylate]]s in [[food]], [[medication]], and [[cosmetics]]
| risks                  = [[Asthma]], [[chronic rhinosinusitis]], [[nasal polyps]]
| diagnosis              = [[Clinical history]], [[elimination diet]], [[oral challenge test]]
| differential            = [[Aspirin-exacerbated respiratory disease]], [[food allergy]], [[intolerance]]
| prevention              = Avoidance of salicylate-containing substances
| treatment              = [[Antihistamines]], [[leukotriene receptor antagonists]], [[corticosteroids]]
| prognosis              = Good with avoidance of triggers
| frequency              = Unknown, varies by population
}}
'''Salicylate sensitivity''' is a condition in which individuals experience adverse reactions to [[salicylates]], a group of chemicals found naturally in many plants and used in various medications, preservatives, and flavorings. Salicylates are present in foods, beverages, and personal care products, and they are also a key ingredient in [[aspirin]] and other non-steroidal anti-inflammatory drugs ([[NSAIDs]]).
==Symptoms==
==Symptoms==
Individuals with salicylate sensitivity may experience a range of symptoms, which can vary in severity. Common symptoms include:
Individuals with salicylate sensitivity may experience a range of symptoms, which can vary in severity. Common symptoms include:
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* [[Fatigue]]
* [[Fatigue]]
* [[Tinnitus]]
* [[Tinnitus]]
==Causes==
==Causes==
The exact cause of salicylate sensitivity is not well understood. It is believed to be related to the body's inability to properly metabolize salicylates. This condition is different from a salicylate allergy, which involves the immune system. Salicylate sensitivity is more common in individuals with [[asthma]], [[chronic rhinosinusitis]], and [[nasal polyps]].
The exact cause of salicylate sensitivity is not well understood. It is believed to be related to the body's inability to properly metabolize salicylates. This condition is different from a salicylate allergy, which involves the immune system. Salicylate sensitivity is more common in individuals with [[asthma]], [[chronic rhinosinusitis]], and [[nasal polyps]].
==Diagnosis==
==Diagnosis==
Diagnosing salicylate sensitivity can be challenging due to the wide range of symptoms and their overlap with other conditions. A diagnosis is typically made based on a patient's medical history, symptom diary, and response to a low-salicylate diet. In some cases, an elimination diet followed by a controlled reintroduction of salicylates may be used to confirm the diagnosis.
Diagnosing salicylate sensitivity can be challenging due to the wide range of symptoms and their overlap with other conditions. A diagnosis is typically made based on a patient's medical history, symptom diary, and response to a low-salicylate diet. In some cases, an elimination diet followed by a controlled reintroduction of salicylates may be used to confirm the diagnosis.
==Management==
==Management==
The primary treatment for salicylate sensitivity is avoiding foods, medications, and products that contain salicylates. This may involve:
The primary treatment for salicylate sensitivity is avoiding foods, medications, and products that contain salicylates. This may involve:
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* Reading labels on food and personal care products
* Reading labels on food and personal care products
* Consulting with a healthcare provider before taking medications
* Consulting with a healthcare provider before taking medications
==Foods High in Salicylates==
==Foods High in Salicylates==
Some foods that are high in salicylates and may need to be avoided include:
Some foods that are high in salicylates and may need to be avoided include:
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* Spices and herbs (e.g., [[curry powder]], [[paprika]], [[thyme]])
* Spices and herbs (e.g., [[curry powder]], [[paprika]], [[thyme]])
* Beverages (e.g., [[tea]], [[coffee]], [[fruit juices]])
* Beverages (e.g., [[tea]], [[coffee]], [[fruit juices]])
==Related Conditions==
==Related Conditions==
Salicylate sensitivity is often associated with other conditions, such as:
Salicylate sensitivity is often associated with other conditions, such as:
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* [[Irritable bowel syndrome]] (IBS)
* [[Irritable bowel syndrome]] (IBS)
* [[Chronic urticaria]]
* [[Chronic urticaria]]
==See Also==
==See Also==
* [[Aspirin]]
* [[Aspirin]]
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* [[Food intolerance]]
* [[Food intolerance]]
* [[Allergy]]
* [[Allergy]]
==References==
==References==
{{Reflist}}
{{Reflist}}
==External Links==
==External Links==
{{Commons category|Salicylate sensitivity}}
{{Commons category|Salicylate sensitivity}}
[[Category:Medical conditions]]
[[Category:Medical conditions]]
[[Category:Allergology]]
[[Category:Allergology]]
[[Category:Food science]]
[[Category:Food science]]
[[Category:Pharmacology]]
[[Category:Pharmacology]]
{{medicine-stub}}
{{medicine-stub}}

Latest revision as of 18:03, 8 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Salicylate sensitivity
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Asthma, rhinitis, urticaria, angioedema, abdominal pain, diarrhea
Complications N/A
Onset Variable, often within hours of exposure
Duration Variable, symptoms may persist as long as exposure continues
Types N/A
Causes Salicylates in food, medication, and cosmetics
Risks Asthma, chronic rhinosinusitis, nasal polyps
Diagnosis Clinical history, elimination diet, oral challenge test
Differential diagnosis Aspirin-exacerbated respiratory disease, food allergy, intolerance
Prevention Avoidance of salicylate-containing substances
Treatment Antihistamines, leukotriene receptor antagonists, corticosteroids
Medication N/A
Prognosis Good with avoidance of triggers
Frequency Unknown, varies by population
Deaths N/A


Salicylate sensitivity is a condition in which individuals experience adverse reactions to salicylates, a group of chemicals found naturally in many plants and used in various medications, preservatives, and flavorings. Salicylates are present in foods, beverages, and personal care products, and they are also a key ingredient in aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs).

Symptoms[edit]

Individuals with salicylate sensitivity may experience a range of symptoms, which can vary in severity. Common symptoms include:

Causes[edit]

The exact cause of salicylate sensitivity is not well understood. It is believed to be related to the body's inability to properly metabolize salicylates. This condition is different from a salicylate allergy, which involves the immune system. Salicylate sensitivity is more common in individuals with asthma, chronic rhinosinusitis, and nasal polyps.

Diagnosis[edit]

Diagnosing salicylate sensitivity can be challenging due to the wide range of symptoms and their overlap with other conditions. A diagnosis is typically made based on a patient's medical history, symptom diary, and response to a low-salicylate diet. In some cases, an elimination diet followed by a controlled reintroduction of salicylates may be used to confirm the diagnosis.

Management[edit]

The primary treatment for salicylate sensitivity is avoiding foods, medications, and products that contain salicylates. This may involve:

  • Following a low-salicylate diet
  • Reading labels on food and personal care products
  • Consulting with a healthcare provider before taking medications

Foods High in Salicylates[edit]

Some foods that are high in salicylates and may need to be avoided include:

Related Conditions[edit]

Salicylate sensitivity is often associated with other conditions, such as:

See Also[edit]

References[edit]

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External Links[edit]

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