Salicylate sensitivity: Difference between revisions
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[[File:Salicylic-acid-skeletal.svg| | {{SI}} | ||
{{Infobox medical condition | |||
| name = Salicylate sensitivity | |||
| image = [[File:Salicylic-acid-skeletal.svg|150px]] | |||
| caption = Skeletal formula of [[salicylic acid]], a common salicylate | |||
| field = [[Allergy and immunology]] | |||
| symptoms = [[Asthma]], [[rhinitis]], [[urticaria]], [[angioedema]], [[abdominal pain]], [[diarrhea]] | |||
| onset = Variable, often within hours of exposure | |||
| duration = Variable, symptoms may persist as long as exposure continues | |||
| causes = [[Salicylate]]s in [[food]], [[medication]], and [[cosmetics]] | |||
| risks = [[Asthma]], [[chronic rhinosinusitis]], [[nasal polyps]] | |||
| diagnosis = [[Clinical history]], [[elimination diet]], [[oral challenge test]] | |||
| differential = [[Aspirin-exacerbated respiratory disease]], [[food allergy]], [[intolerance]] | |||
| prevention = Avoidance of salicylate-containing substances | |||
| treatment = [[Antihistamines]], [[leukotriene receptor antagonists]], [[corticosteroids]] | |||
| prognosis = Good with avoidance of triggers | |||
| frequency = Unknown, varies by population | |||
}} | |||
'''Salicylate sensitivity''' is a condition in which individuals experience adverse reactions to [[salicylates]], a group of chemicals found naturally in many plants and used in various medications, preservatives, and flavorings. Salicylates are present in foods, beverages, and personal care products, and they are also a key ingredient in [[aspirin]] and other non-steroidal anti-inflammatory drugs ([[NSAIDs]]). | |||
==Symptoms== | ==Symptoms== | ||
Individuals with salicylate sensitivity may experience a range of symptoms, which can vary in severity. Common symptoms include: | Individuals with salicylate sensitivity may experience a range of symptoms, which can vary in severity. Common symptoms include: | ||
| Line 11: | Line 28: | ||
* [[Fatigue]] | * [[Fatigue]] | ||
* [[Tinnitus]] | * [[Tinnitus]] | ||
==Causes== | ==Causes== | ||
The exact cause of salicylate sensitivity is not well understood. It is believed to be related to the body's inability to properly metabolize salicylates. This condition is different from a salicylate allergy, which involves the immune system. Salicylate sensitivity is more common in individuals with [[asthma]], [[chronic rhinosinusitis]], and [[nasal polyps]]. | The exact cause of salicylate sensitivity is not well understood. It is believed to be related to the body's inability to properly metabolize salicylates. This condition is different from a salicylate allergy, which involves the immune system. Salicylate sensitivity is more common in individuals with [[asthma]], [[chronic rhinosinusitis]], and [[nasal polyps]]. | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosing salicylate sensitivity can be challenging due to the wide range of symptoms and their overlap with other conditions. A diagnosis is typically made based on a patient's medical history, symptom diary, and response to a low-salicylate diet. In some cases, an elimination diet followed by a controlled reintroduction of salicylates may be used to confirm the diagnosis. | Diagnosing salicylate sensitivity can be challenging due to the wide range of symptoms and their overlap with other conditions. A diagnosis is typically made based on a patient's medical history, symptom diary, and response to a low-salicylate diet. In some cases, an elimination diet followed by a controlled reintroduction of salicylates may be used to confirm the diagnosis. | ||
==Management== | ==Management== | ||
The primary treatment for salicylate sensitivity is avoiding foods, medications, and products that contain salicylates. This may involve: | The primary treatment for salicylate sensitivity is avoiding foods, medications, and products that contain salicylates. This may involve: | ||
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* Reading labels on food and personal care products | * Reading labels on food and personal care products | ||
* Consulting with a healthcare provider before taking medications | * Consulting with a healthcare provider before taking medications | ||
==Foods High in Salicylates== | ==Foods High in Salicylates== | ||
Some foods that are high in salicylates and may need to be avoided include: | Some foods that are high in salicylates and may need to be avoided include: | ||
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* Spices and herbs (e.g., [[curry powder]], [[paprika]], [[thyme]]) | * Spices and herbs (e.g., [[curry powder]], [[paprika]], [[thyme]]) | ||
* Beverages (e.g., [[tea]], [[coffee]], [[fruit juices]]) | * Beverages (e.g., [[tea]], [[coffee]], [[fruit juices]]) | ||
==Related Conditions== | ==Related Conditions== | ||
Salicylate sensitivity is often associated with other conditions, such as: | Salicylate sensitivity is often associated with other conditions, such as: | ||
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* [[Irritable bowel syndrome]] (IBS) | * [[Irritable bowel syndrome]] (IBS) | ||
* [[Chronic urticaria]] | * [[Chronic urticaria]] | ||
==See Also== | ==See Also== | ||
* [[Aspirin]] | * [[Aspirin]] | ||
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* [[Food intolerance]] | * [[Food intolerance]] | ||
* [[Allergy]] | * [[Allergy]] | ||
==References== | ==References== | ||
{{Reflist}} | {{Reflist}} | ||
==External Links== | ==External Links== | ||
{{Commons category|Salicylate sensitivity}} | {{Commons category|Salicylate sensitivity}} | ||
[[Category:Medical conditions]] | [[Category:Medical conditions]] | ||
[[Category:Allergology]] | [[Category:Allergology]] | ||
[[Category:Food science]] | [[Category:Food science]] | ||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
{{medicine-stub}} | {{medicine-stub}} | ||
Latest revision as of 18:03, 8 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Salicylate sensitivity | |
|---|---|
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Asthma, rhinitis, urticaria, angioedema, abdominal pain, diarrhea |
| Complications | N/A |
| Onset | Variable, often within hours of exposure |
| Duration | Variable, symptoms may persist as long as exposure continues |
| Types | N/A |
| Causes | Salicylates in food, medication, and cosmetics |
| Risks | Asthma, chronic rhinosinusitis, nasal polyps |
| Diagnosis | Clinical history, elimination diet, oral challenge test |
| Differential diagnosis | Aspirin-exacerbated respiratory disease, food allergy, intolerance |
| Prevention | Avoidance of salicylate-containing substances |
| Treatment | Antihistamines, leukotriene receptor antagonists, corticosteroids |
| Medication | N/A |
| Prognosis | Good with avoidance of triggers |
| Frequency | Unknown, varies by population |
| Deaths | N/A |
Salicylate sensitivity is a condition in which individuals experience adverse reactions to salicylates, a group of chemicals found naturally in many plants and used in various medications, preservatives, and flavorings. Salicylates are present in foods, beverages, and personal care products, and they are also a key ingredient in aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs).
Symptoms[edit]
Individuals with salicylate sensitivity may experience a range of symptoms, which can vary in severity. Common symptoms include:
- Headache
- Nasal congestion
- Asthma-like symptoms
- Skin rash
- Stomach pain
- Diarrhea
- Fatigue
- Tinnitus
Causes[edit]
The exact cause of salicylate sensitivity is not well understood. It is believed to be related to the body's inability to properly metabolize salicylates. This condition is different from a salicylate allergy, which involves the immune system. Salicylate sensitivity is more common in individuals with asthma, chronic rhinosinusitis, and nasal polyps.
Diagnosis[edit]
Diagnosing salicylate sensitivity can be challenging due to the wide range of symptoms and their overlap with other conditions. A diagnosis is typically made based on a patient's medical history, symptom diary, and response to a low-salicylate diet. In some cases, an elimination diet followed by a controlled reintroduction of salicylates may be used to confirm the diagnosis.
Management[edit]
The primary treatment for salicylate sensitivity is avoiding foods, medications, and products that contain salicylates. This may involve:
- Following a low-salicylate diet
- Reading labels on food and personal care products
- Consulting with a healthcare provider before taking medications
Foods High in Salicylates[edit]
Some foods that are high in salicylates and may need to be avoided include:
- Certain fruits (e.g., berries, grapes, oranges)
- Certain vegetables (e.g., tomatoes, broccoli, spinach)
- Spices and herbs (e.g., curry powder, paprika, thyme)
- Beverages (e.g., tea, coffee, fruit juices)
Related Conditions[edit]
Salicylate sensitivity is often associated with other conditions, such as:
See Also[edit]
References[edit]
<references group="" responsive="1"></references>
External Links[edit]
