Drug-induced keratoderma: Difference between revisions
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{{Infobox medical condition | |||
| name = Drug-induced keratoderma | |||
| synonyms = | |||
| specialty = [[Dermatology]] | |||
| symptoms = Thickening of the [[skin]] on the [[palms]] and [[soles]] | |||
| complications = | |||
| onset = | |||
| duration = | |||
| causes = [[Drug reaction]] | |||
| risks = | |||
| diagnosis = [[Clinical diagnosis]] | |||
| differential = [[Palmoplantar keratoderma]], [[Psoriasis]], [[Eczema]] | |||
| prevention = Avoidance of causative drugs | |||
| treatment = Discontinuation of the offending drug, [[topical treatment]]s | |||
| medication = [[Keratolytics]], [[Emollients]] | |||
| prognosis = Generally good with drug discontinuation | |||
| frequency = Rare | |||
}} | |||
'''Drug-induced keratoderma''' is a condition characterized by the thickening of the skin on the palms of the hands and the soles of the feet. This condition is caused by the use of certain medications. | '''Drug-induced keratoderma''' is a condition characterized by the thickening of the skin on the palms of the hands and the soles of the feet. This condition is caused by the use of certain medications. | ||
== Causes == | == Causes == | ||
Drug-induced keratoderma is caused by the use of certain medications. These medications include [[retinoids]], [[cytotoxic drugs]], and [[antiretroviral drugs]]. The exact mechanism by which these drugs cause keratoderma is not fully understood. | Drug-induced keratoderma is caused by the use of certain medications. These medications include [[retinoids]], [[cytotoxic drugs]], and [[antiretroviral drugs]]. The exact mechanism by which these drugs cause keratoderma is not fully understood. | ||
== Symptoms == | == Symptoms == | ||
The main symptom of drug-induced keratoderma is the thickening of the skin on the palms of the hands and the soles of the feet. This thickening can be accompanied by other symptoms such as redness, itching, and pain. | The main symptom of drug-induced keratoderma is the thickening of the skin on the palms of the hands and the soles of the feet. This thickening can be accompanied by other symptoms such as redness, itching, and pain. | ||
== Diagnosis == | == Diagnosis == | ||
The diagnosis of drug-induced keratoderma is made based on the patient's medical history, physical examination, and the results of skin biopsy. The skin biopsy can show characteristic changes in the skin that are indicative of keratoderma. | The diagnosis of drug-induced keratoderma is made based on the patient's medical history, physical examination, and the results of skin biopsy. The skin biopsy can show characteristic changes in the skin that are indicative of keratoderma. | ||
== Treatment == | == Treatment == | ||
The treatment of drug-induced keratoderma involves discontinuing the offending medication and treating the symptoms. Topical treatments such as [[emollients]] and [[keratolytics]] can be used to soften the skin and reduce the thickness of the skin. In severe cases, systemic treatments such as [[retinoids]] may be used. | The treatment of drug-induced keratoderma involves discontinuing the offending medication and treating the symptoms. Topical treatments such as [[emollients]] and [[keratolytics]] can be used to soften the skin and reduce the thickness of the skin. In severe cases, systemic treatments such as [[retinoids]] may be used. | ||
== See also == | == See also == | ||
* [[Keratoderma]] | * [[Keratoderma]] | ||
* [[Drug-induced conditions]] | * [[Drug-induced conditions]] | ||
* [[Skin conditions]] | * [[Skin conditions]] | ||
[[Category:Skin conditions]] | [[Category:Skin conditions]] | ||
[[Category:Drug-induced conditions]] | [[Category:Drug-induced conditions]] | ||
{{stub}} | {{stub}} | ||
{{No image}} | {{No image}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 05:48, 4 April 2025
| Drug-induced keratoderma | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | Dermatology |
| Symptoms | Thickening of the skin on the palms and soles |
| Complications | |
| Onset | |
| Duration | |
| Types | N/A |
| Causes | Drug reaction |
| Risks | |
| Diagnosis | Clinical diagnosis |
| Differential diagnosis | Palmoplantar keratoderma, Psoriasis, Eczema |
| Prevention | Avoidance of causative drugs |
| Treatment | Discontinuation of the offending drug, topical treatments |
| Medication | Keratolytics, Emollients |
| Prognosis | Generally good with drug discontinuation |
| Frequency | Rare |
| Deaths | N/A |
Drug-induced keratoderma is a condition characterized by the thickening of the skin on the palms of the hands and the soles of the feet. This condition is caused by the use of certain medications.
Causes[edit]
Drug-induced keratoderma is caused by the use of certain medications. These medications include retinoids, cytotoxic drugs, and antiretroviral drugs. The exact mechanism by which these drugs cause keratoderma is not fully understood.
Symptoms[edit]
The main symptom of drug-induced keratoderma is the thickening of the skin on the palms of the hands and the soles of the feet. This thickening can be accompanied by other symptoms such as redness, itching, and pain.
Diagnosis[edit]
The diagnosis of drug-induced keratoderma is made based on the patient's medical history, physical examination, and the results of skin biopsy. The skin biopsy can show characteristic changes in the skin that are indicative of keratoderma.
Treatment[edit]
The treatment of drug-induced keratoderma involves discontinuing the offending medication and treating the symptoms. Topical treatments such as emollients and keratolytics can be used to soften the skin and reduce the thickness of the skin. In severe cases, systemic treatments such as retinoids may be used.
