Cholestasis facies: Difference between revisions
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{{Infobox medical condition | |||
| name = Cholestasis facies | |||
| synonyms = | |||
| image = | |||
| caption = | |||
| field = [[Hepatology]] | |||
| symptoms = [[Jaundice]], [[pruritus]], [[dark urine]], [[pale stools]], [[fatigue]] | |||
| complications = [[Liver cirrhosis]], [[liver failure]], [[osteoporosis]] | |||
| onset = Varies depending on underlying cause | |||
| duration = Can be acute or chronic | |||
| causes = [[Bile duct obstruction]], [[liver disease]], [[genetic disorders]] | |||
| risks = [[Gallstones]], [[alcohol abuse]], [[hepatitis]], [[primary biliary cholangitis]] | |||
| diagnosis = [[Blood tests]], [[imaging studies]], [[liver biopsy]] | |||
| differential = [[Hepatitis]], [[Gilbert's syndrome]], [[Dubin-Johnson syndrome]] | |||
| treatment = [[Ursodeoxycholic acid]], [[cholestyramine]], [[liver transplant]] | |||
| prognosis = Depends on underlying cause and treatment | |||
| frequency = Varies globally, more common in certain populations | |||
}} | |||
'''Cholestasis facies''' is a medical condition characterized by a distinctive facial appearance due to prolonged [[cholestasis]], a condition where the flow of [[bile]] from the [[liver]] is slowed or blocked. This condition is often associated with various [[liver diseases]] and [[genetic disorders]]. | '''Cholestasis facies''' is a medical condition characterized by a distinctive facial appearance due to prolonged [[cholestasis]], a condition where the flow of [[bile]] from the [[liver]] is slowed or blocked. This condition is often associated with various [[liver diseases]] and [[genetic disorders]]. | ||
== Symptoms == | == Symptoms == | ||
The primary symptom of cholestasis facies is a distinctive facial appearance, which can include: | The primary symptom of cholestasis facies is a distinctive facial appearance, which can include: | ||
* [[Jaundice]] (yellowing of the skin and eyes) | * [[Jaundice]] (yellowing of the skin and eyes) | ||
* [[Pruritus]] (itching) | * [[Pruritus]] (itching) | ||
| Line 11: | Line 27: | ||
* [[Fatigue]] | * [[Fatigue]] | ||
* [[Loss of appetite]] | * [[Loss of appetite]] | ||
== Causes == | == Causes == | ||
Cholestasis facies can be caused by a variety of conditions that affect the liver's ability to produce or release bile. These can include: | Cholestasis facies can be caused by a variety of conditions that affect the liver's ability to produce or release bile. These can include: | ||
* [[Liver cirrhosis]] | * [[Liver cirrhosis]] | ||
* [[Hepatitis]] | * [[Hepatitis]] | ||
| Line 23: | Line 36: | ||
* [[Primary sclerosing cholangitis]] | * [[Primary sclerosing cholangitis]] | ||
* Certain genetic disorders, such as [[Alagille syndrome]] | * Certain genetic disorders, such as [[Alagille syndrome]] | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of cholestasis facies is typically based on the distinctive facial appearance, along with other symptoms of cholestasis. Additional tests may be performed to determine the underlying cause, such as: | Diagnosis of cholestasis facies is typically based on the distinctive facial appearance, along with other symptoms of cholestasis. Additional tests may be performed to determine the underlying cause, such as: | ||
* [[Blood tests]] | * [[Blood tests]] | ||
* [[Liver function tests]] | * [[Liver function tests]] | ||
* [[Imaging tests]], such as an [[ultrasound]] or [[MRI]] | * [[Imaging tests]], such as an [[ultrasound]] or [[MRI]] | ||
* [[Liver biopsy]] | * [[Liver biopsy]] | ||
== Treatment == | == Treatment == | ||
Treatment for cholestasis facies focuses on addressing the underlying cause of the cholestasis. This can include: | Treatment for cholestasis facies focuses on addressing the underlying cause of the cholestasis. This can include: | ||
* Medications to improve bile flow | * Medications to improve bile flow | ||
* Medications to relieve symptoms, such as itching | * Medications to relieve symptoms, such as itching | ||
* Surgery to remove gallstones or treat biliary atresia | * Surgery to remove gallstones or treat biliary atresia | ||
* Liver transplant in severe cases | * Liver transplant in severe cases | ||
== See also == | == See also == | ||
* [[Cholestasis]] | * [[Cholestasis]] | ||
* [[Liver disease]] | * [[Liver disease]] | ||
* [[Biliary atresia]] | * [[Biliary atresia]] | ||
* [[Alagille syndrome]] | * [[Alagille syndrome]] | ||
[[Category:Medical conditions]] | [[Category:Medical conditions]] | ||
[[Category:Liver diseases]] | [[Category:Liver diseases]] | ||
[[Category:Genetic disorders]] | [[Category:Genetic disorders]] | ||
{{stub}} | {{stub}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 22:51, 3 April 2025
| Cholestasis facies | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Jaundice, pruritus, dark urine, pale stools, fatigue |
| Complications | Liver cirrhosis, liver failure, osteoporosis |
| Onset | Varies depending on underlying cause |
| Duration | Can be acute or chronic |
| Types | N/A |
| Causes | Bile duct obstruction, liver disease, genetic disorders |
| Risks | Gallstones, alcohol abuse, hepatitis, primary biliary cholangitis |
| Diagnosis | Blood tests, imaging studies, liver biopsy |
| Differential diagnosis | Hepatitis, Gilbert's syndrome, Dubin-Johnson syndrome |
| Prevention | N/A |
| Treatment | Ursodeoxycholic acid, cholestyramine, liver transplant |
| Medication | N/A |
| Prognosis | Depends on underlying cause and treatment |
| Frequency | Varies globally, more common in certain populations |
| Deaths | N/A |
Cholestasis facies is a medical condition characterized by a distinctive facial appearance due to prolonged cholestasis, a condition where the flow of bile from the liver is slowed or blocked. This condition is often associated with various liver diseases and genetic disorders.
Symptoms[edit]
The primary symptom of cholestasis facies is a distinctive facial appearance, which can include:
- Jaundice (yellowing of the skin and eyes)
- Pruritus (itching)
- Dark urine
- Pale stools
- Fatigue
- Loss of appetite
Causes[edit]
Cholestasis facies can be caused by a variety of conditions that affect the liver's ability to produce or release bile. These can include:
- Liver cirrhosis
- Hepatitis
- Gallstones
- Biliary atresia
- Primary biliary cirrhosis
- Primary sclerosing cholangitis
- Certain genetic disorders, such as Alagille syndrome
Diagnosis[edit]
Diagnosis of cholestasis facies is typically based on the distinctive facial appearance, along with other symptoms of cholestasis. Additional tests may be performed to determine the underlying cause, such as:
- Blood tests
- Liver function tests
- Imaging tests, such as an ultrasound or MRI
- Liver biopsy
Treatment[edit]
Treatment for cholestasis facies focuses on addressing the underlying cause of the cholestasis. This can include:
- Medications to improve bile flow
- Medications to relieve symptoms, such as itching
- Surgery to remove gallstones or treat biliary atresia
- Liver transplant in severe cases


