Tienoxolol: Difference between revisions
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{{Short description|An article about the beta-blocker Tienoxolol}} | |||
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| image_alt = Structural formula of Tienoxolol | |||
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'''Tienoxolol''' is a [[beta-adrenergic receptor antagonist]] (beta-blocker) used in the management of [[hypertension]] and other cardiovascular conditions. It is known for its selective action on beta-1 adrenergic receptors, which are primarily located in the heart. | |||
Tienoxolol | |||
== | ==Pharmacology== | ||
== | ===Mechanism of Action=== | ||
Tienoxolol works by blocking the beta-1 adrenergic receptors in the heart, leading to a decrease in heart rate and cardiac output. This action reduces the workload on the heart and lowers [[blood pressure]]. Unlike non-selective beta-blockers, Tienoxolol has minimal effects on beta-2 receptors, which are found in the lungs and vascular smooth muscle. | |||
== | ===Pharmacokinetics=== | ||
Tienoxolol is administered orally and is well absorbed from the gastrointestinal tract. It undergoes hepatic metabolism and is excreted primarily in the urine. The drug has a half-life that allows for once-daily dosing, which can improve patient compliance. | |||
== | ==Clinical Uses== | ||
Tienoxolol is | Tienoxolol is primarily used in the treatment of hypertension. It may also be used in the management of [[angina pectoris]] and in the prevention of [[myocardial infarction]]. | ||
== | ==Side Effects== | ||
Tienoxolol | Common side effects of Tienoxolol include [[bradycardia]], [[fatigue]], and [[dizziness]]. As with other beta-blockers, it may cause or exacerbate [[bronchospasm]] in susceptible individuals, such as those with [[asthma]]. | ||
== | ==Contraindications== | ||
Tienoxolol is contraindicated in patients with [[bradycardia]], [[heart block]], and [[cardiogenic shock]]. Caution is advised in patients with [[diabetes mellitus]] and [[chronic obstructive pulmonary disease]] (COPD). | |||
==Related pages== | |||
* [[Beta blocker]] | |||
* [[Hypertension]] | |||
* [[Cardiovascular disease]] | |||
[[Category:Beta blockers]] | [[Category:Beta blockers]] | ||
[[Category: | [[Category:Antihypertensive agents]] | ||
Latest revision as of 04:01, 13 February 2025
An article about the beta-blocker Tienoxolol
Tienoxolol is a beta-adrenergic receptor antagonist (beta-blocker) used in the management of hypertension and other cardiovascular conditions. It is known for its selective action on beta-1 adrenergic receptors, which are primarily located in the heart.
Pharmacology[edit]
Mechanism of Action[edit]
Tienoxolol works by blocking the beta-1 adrenergic receptors in the heart, leading to a decrease in heart rate and cardiac output. This action reduces the workload on the heart and lowers blood pressure. Unlike non-selective beta-blockers, Tienoxolol has minimal effects on beta-2 receptors, which are found in the lungs and vascular smooth muscle.
Pharmacokinetics[edit]
Tienoxolol is administered orally and is well absorbed from the gastrointestinal tract. It undergoes hepatic metabolism and is excreted primarily in the urine. The drug has a half-life that allows for once-daily dosing, which can improve patient compliance.
Clinical Uses[edit]
Tienoxolol is primarily used in the treatment of hypertension. It may also be used in the management of angina pectoris and in the prevention of myocardial infarction.
Side Effects[edit]
Common side effects of Tienoxolol include bradycardia, fatigue, and dizziness. As with other beta-blockers, it may cause or exacerbate bronchospasm in susceptible individuals, such as those with asthma.
Contraindications[edit]
Tienoxolol is contraindicated in patients with bradycardia, heart block, and cardiogenic shock. Caution is advised in patients with diabetes mellitus and chronic obstructive pulmonary disease (COPD).
