Virtual Physiological Human

Virtual Physiological Human (VPH) is a methodological and technological framework that, once established, will enable collaborative investigation of the human body as a single complex system. The collective framework will use all current models and data on human biology and health to simulate the internal workings of the body.

Overview

The Virtual Physiological Human project is an initiative by the European Commission to develop a methodological and technological framework that will enable the investigation of the human body as a single complex system. The goal of the VPH project is to deliver a framework that can integrate data from all levels of biological organization to result in a unified understanding of human physiology and pathology.

Methodology

The VPH methodology involves the integration of various types of data from multiple sources. This includes genomic data, proteomic data, metabolomic data, and anatomical data. These data are then used to create computational models of the human body, which can be used to simulate and analyze physiological processes.

Applications

The applications of the VPH are vast and varied. They include the development of personalized medicine, improved diagnostic techniques, and the creation of new therapeutic strategies. The VPH can also be used in the field of drug discovery, where it can help to predict the effects of potential drugs on the human body.

Challenges

Despite its potential, the VPH also faces several challenges. These include the need for large-scale data integration, the development of robust and reliable computational models, and the need for validation of these models. Furthermore, ethical and legal issues related to data privacy and ownership also need to be addressed.

See also

• In silico medicine
• Systems biology
• Computational biology
• Bioinformatics

References

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