Trichoblastoma
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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| Trichoblastoma | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Skin tumor |
| Complications | Rarely malignant transformation |
| Onset | |
| Duration | |
| Types | |
| Causes | Unknown |
| Risks | |
| Diagnosis | Histopathology |
| Differential diagnosis | Basal cell carcinoma, Trichoepithelioma |
| Prevention | |
| Treatment | Surgical excision |
| Medication | |
| Prognosis | Generally good |
| Frequency | Rare |
| Deaths | N/A |
Trichoblastoma is a rare, benign skin tumor that originates from the hair follicles. It is considered a type of follicular neoplasm and is often found on the scalp and face.
Presentation[edit]
Trichoblastomas typically present as solitary, slow-growing nodules. They are usually skin-colored or slightly pigmented and can vary in size. These tumors are most commonly diagnosed in adults, although they can occur at any age.
Histopathology[edit]
Under the microscope, trichoblastomas are characterized by nests of basaloid cells that resemble the germinal matrix of the hair follicle. The tumor cells are often arranged in a trabecular or ribbon-like pattern. The stroma surrounding the tumor nests is typically fibrous and may contain mucin.
Differential Diagnosis[edit]
Trichoblastoma must be differentiated from other basaloid tumors such as basal cell carcinoma and trichoepithelioma. Unlike basal cell carcinoma, trichoblastomas do not exhibit peripheral palisading or stromal retraction.
Treatment[edit]
The primary treatment for trichoblastoma is surgical excision. Complete removal is usually curative, and recurrence is rare. Due to their benign nature, trichoblastomas do not metastasize.
Related Conditions[edit]
Trichoblastomas are part of a spectrum of follicular tumors that include trichoepithelioma and pilomatricoma. These tumors share a common origin from the hair follicle but differ in their clinical and histological features.
See also[edit]
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