Tricaprin

A triglyceride compound

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Tricaprin, also known as glycerol tridecanoate, is a triglyceride composed of three decanoic acid molecules esterified to a glycerol backbone. It is a type of medium-chain triglyceride (MCT) and is used in various applications, including nutritional supplements, pharmaceuticals, and cosmetics.

Chemical Structure and Properties

Tricaprin is a saturated fat with the chemical formula C₃₃H₆₂O₆. It is a white, waxy solid at room temperature and is insoluble in water but soluble in organic solvents such as ethanol and chloroform. The compound has a melting point of approximately 31-33°C.

Structural formula of tricaprin

Synthesis

Tricaprin can be synthesized through the esterification of glycerol with decanoic acid. This reaction typically involves the use of an acid catalyst, such as sulfuric acid, to facilitate the formation of ester bonds between the hydroxyl groups of glycerol and the carboxyl groups of decanoic acid.

Applications

Nutritional Supplements

Tricaprin is used in dietary supplements due to its status as a medium-chain triglyceride. MCTs are known for their rapid absorption and metabolism, providing a quick source of energy. They are often included in ketogenic diets and are used by athletes and individuals seeking to manage their weight.

Pharmaceuticals

In the pharmaceutical industry, tricaprin is used as an excipient in the formulation of various drug delivery systems. Its ability to enhance the solubility and bioavailability of poorly water-soluble drugs makes it a valuable component in oral and topical formulations.

Cosmetics

Tricaprin is also utilized in the cosmetic industry as an emollient and skin-conditioning agent. It is included in creams, lotions, and other personal care products to improve texture and provide moisturizing benefits.

Health Effects

The consumption of tricaprin, as part of MCTs, has been associated with several health benefits, including improved cognitive function, enhanced metabolism, and support for weight management. However, excessive intake may lead to gastrointestinal discomfort in some individuals.

Related Compounds

• Trilaurin
• Trimyristin
• Tripalmitin

Related Pages

• Medium-chain triglyceride
• Decanoic acid
• Glycerol