Toxic leukoencephalopathy
| Toxic leukoencephalopathy | |
|---|---|
| Synonyms | Toxic spongiform leukoencephalopathy |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Cognitive impairment, ataxia, seizures, coma |
| Complications | Permanent neurological damage, death |
| Onset | Acute or subacute |
| Duration | Variable, depending on exposure and treatment |
| Types | N/A |
| Causes | Exposure to toxic substances such as chemotherapy agents, recreational drugs, environmental toxins |
| Risks | High-dose or prolonged exposure to toxic agents |
| Diagnosis | MRI, clinical evaluation |
| Differential diagnosis | Multiple sclerosis, infectious leukoencephalopathy, metabolic disorders |
| Prevention | N/A |
| Treatment | Removal of the toxic agent, supportive care, rehabilitation |
| Medication | N/A |
| Prognosis | Variable; can range from full recovery to severe disability or death |
| Frequency | Rare |
| Deaths | N/A |
Third-hand smoke is the residual contamination from tobacco smoke that adheres to any surface, long after the smoking activity has ceased. This residue is thought to react with common indoor pollutants to create a toxic mix. This toxic mix of Third-hand smoke contains cancer-causing substances, posing a potential health hazard to nonsmokers who are exposed to it, especially children.
Health Effects
Third-hand smoke poses a significant health risk to non-smokers, particularly children who are more likely to come into contact with contaminated surfaces. The residue from third-hand smoke builds up on surfaces over time and resists normal cleaning. Third-hand smoke can't be eliminated by airing out rooms, opening windows, using fans or air conditioners, or confining smoking to only certain areas of a home.
Exposure
Non-smokers are exposed to third-hand smoke in a variety of ways, including inhaling, swallowing or touching substances containing third-hand smoke. Infants and children might have increased exposure to third-hand smoke due to their tendency to mouth objects and touch affected surfaces.
Prevention
The only way to protect non-smokers from third-hand smoke is to create a smoke-free environment, whether that's in your home or in your vehicle. Consider quitting smoking if you're a smoker. If you have guests who smoke, offer them a place to smoke outside.
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Contributors: Prab R. Tumpati, MD