Tibrovirus

Overview

Electron micrograph of a Tibrovirus particle

Tibrovirus is a genus of viruses in the family Rhabdoviridae. These viruses are known to infect mammals and are primarily transmitted through arthropod vectors. The genus is named after the town of Tibro in Sweden, where the first virus of this genus was isolated.

Structure

Tibroviruses are characterized by their enveloped structure and a helical nucleocapsid. The virions are typically bullet-shaped, a common feature among members of the Rhabdoviridae family. The genome is composed of a single-stranded, negative-sense RNA molecule.

Genome

The genome of Tibroviruses is approximately 11-12 kilobases in length and encodes five proteins. These include the nucleoprotein (N), the phosphoprotein (P), the matrix protein (M), the glycoprotein (G), and the RNA-dependent RNA polymerase (L). The organization of these genes is similar to other rhabdoviruses.

Transmission

Tibroviruses are primarily transmitted through the bites of infected arthropods, such as mosquitoes and ticks. The specific vectors and hosts can vary depending on the virus species within the genus.

Pathogenesis

The pathogenesis of Tibrovirus infections in humans and animals is not well understood. Some Tibroviruses have been associated with mild febrile illnesses in humans, but more research is needed to fully elucidate their clinical significance.

Species

The genus Tibrovirus includes several species, with the most well-known being the Sweetwater branch virus. Other species have been identified, but their roles in disease and ecology are still under investigation.

Research

Research on Tibroviruses is ongoing, with studies focusing on their molecular biology, ecology, and potential impact on human and animal health. Understanding the transmission dynamics and host interactions is crucial for developing strategies to prevent and control infections.

Related pages

• Rhabdoviridae
• Arthropod-borne virus
• Viral pathogenesis