Thyrotoxic myopathy

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Thyrotoxic Myopathy

Thyrotoxic myopathy (/θaɪroʊˈtɒksɪk maɪˈɒpəθi/) is a muscle disorder caused by excessive levels of thyroid hormone in the body.

Etymology

The term "thyrotoxic myopathy" is derived from three Greek words: "thyro" meaning "shield", referring to the thyroid gland's shield-like shape; "toxic" meaning "poison", referring to the harmful effects of excessive thyroid hormone; and "myopathy" meaning "muscle disease".

Definition

Thyrotoxic myopathy is a condition characterized by muscle weakness and wasting due to an overactive thyroid, also known as hyperthyroidism. The most common cause of hyperthyroidism is Graves' disease, an autoimmune disorder that leads to overproduction of thyroid hormones.

Symptoms

Symptoms of thyrotoxic myopathy may include muscle weakness, particularly in the upper arms and thighs, difficulty climbing stairs or lifting heavy objects, and in severe cases, muscle wasting. Other symptoms related to hyperthyroidism, such as rapid heart rate, weight loss, and tremors, may also be present.

Diagnosis

Diagnosis of thyrotoxic myopathy typically involves blood tests to measure levels of thyroid hormones and thyroid-stimulating hormone (TSH). Electromyography (EMG) and muscle biopsy may also be used to confirm the diagnosis and rule out other causes of muscle weakness.

Treatment

Treatment for thyrotoxic myopathy involves addressing the underlying hyperthyroidism. This may include medication to reduce thyroid hormone production, radioactive iodine therapy, or surgery to remove part or all of the thyroid gland. Physical therapy may also be recommended to help improve muscle strength and function.

Related Terms

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