Thromboxane a2
Thromboxane A2
Thromboxane A2 (pronunciation: throm-box-ane A-2) is a type of thromboxane that is produced in platelets and has a role in hemostasis. It is a member of the eicosanoid family of lipid mediators and is known for its potent ability to stimulate platelet aggregation.
Etymology
The term "Thromboxane" is derived from its role in thrombosis and its oxygen-containing cyclic ether structure (oxane). The "A2" denotes its specific subtype within the thromboxane family.
Function
Thromboxane A2 is produced by platelets during blood clotting. It promotes vasoconstriction and platelet aggregation, which are crucial steps in the clotting process. It is synthesized from prostaglandin H2 via the action of the enzyme thromboxane-A synthase.
Related Terms
- Thromboxane-A synthase: The enzyme responsible for the synthesis of Thromboxane A2.
- Prostaglandin H2: The precursor molecule from which Thromboxane A2 is synthesized.
- Eicosanoid: A family of lipid mediators that includes Thromboxane A2.
- Platelets: Cell fragments in the blood that are involved in clotting and produce Thromboxane A2.
- Vasoconstriction: The narrowing of blood vessels, a process promoted by Thromboxane A2.
- Hemostasis: The process of stopping bleeding, in which Thromboxane A2 plays a role.
See Also
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