Synovial osteochondromatosis
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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| Synovial osteochondromatosis | |
|---|---|
| Synonyms | Synovial chondromatosis, synovial chondrometaplasia |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Joint pain, swelling, reduced range of motion |
| Complications | Osteoarthritis, joint degeneration |
| Onset | Typically between ages 30 and 50 |
| Duration | Chronic |
| Types | N/A |
| Causes | Unknown, possibly related to trauma or inflammation |
| Risks | Recurrent joint trauma, genetic predisposition |
| Diagnosis | X-ray, MRI, arthroscopy |
| Differential diagnosis | Osteoarthritis, rheumatoid arthritis, gout |
| Prevention | N/A |
| Treatment | Arthroscopic surgery, synovectomy, removal of loose bodies |
| Medication | NSAIDs for pain management |
| Prognosis | Generally good with treatment, but may recur |
| Frequency | Rare |
| Deaths | N/A |
Synovial osteochondromatosis is a rare, benign condition characterized by the formation of cartilaginous nodules in the synovial membrane of joints, tendon sheaths, or bursae. These nodules can become detached and form loose bodies within the joint space, leading to joint pain, swelling, and reduced range of motion.
Pathophysiology
The exact cause of synovial osteochondromatosis is not well understood. It is thought to result from metaplasia of the synovial membrane, where the synovial cells transform into chondrocytes, producing cartilage. Over time, these cartilaginous nodules may calcify or ossify, becoming loose bodies within the joint.
Clinical Presentation
Patients with synovial osteochondromatosis typically present with joint pain, swelling, and stiffness. The condition most commonly affects the knee joint, but it can also occur in the hip joint, shoulder joint, elbow joint, and ankle joint. The presence of loose bodies can lead to mechanical symptoms such as locking or clicking of the joint.
Diagnosis
Diagnosis of synovial osteochondromatosis is primarily based on clinical examination and imaging studies. X-ray imaging may reveal calcified loose bodies within the joint. Magnetic resonance imaging (MRI) is more sensitive and can show both calcified and non-calcified nodules, as well as any associated synovial proliferation.
Treatment
The treatment of synovial osteochondromatosis often involves surgical intervention. Arthroscopy is commonly used to remove loose bodies and to perform synovectomy, which is the removal of the affected synovial tissue. In some cases, open surgery may be necessary, especially if there is extensive involvement of the joint.
Prognosis
The prognosis for patients with synovial osteochondromatosis is generally good following surgical treatment. However, there is a risk of recurrence, and patients may require follow-up to monitor for any new symptoms or the reformation of loose bodies.
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Contributors: Prab R. Tumpati, MD