Sympatholytics

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Sympatholytics

Sympatholytics (pronounced sim-puh-tho-LIT-iks) are a class of drugs that inhibit the postganglionic functioning of the sympathetic nervous system (SNS). They are also known as antiadrenergic agents or adrenergic antagonists.

Etymology

The term "sympatholytic" is derived from the Greek words "sympatheia" meaning "sympathy" and "lysis" meaning "loosening or dissolving". It refers to the drug's ability to 'dissolve' or inhibit the effects of the sympathetic nervous system.

Function

Sympatholytics work by blocking the action of catecholamines, such as norepinephrine and epinephrine, on the sympathetic nervous system. They are used to treat a variety of conditions, including hypertension, anxiety disorders, and glaucoma.

Types of Sympatholytics

There are several types of sympatholytics, including:

  • Alpha blockers, which inhibit the action of norepinephrine on alpha receptors.
  • Beta blockers, which inhibit the action of epinephrine and norepinephrine on beta receptors.
  • Ganglionic blockers, which inhibit the transmission of nerve impulses in the autonomic ganglia.

Related Terms

  • Sympathomimetics: These are drugs that mimic the effects of the sympathetic nervous system.
  • Parasympatholytics: These are drugs that inhibit the action of the parasympathetic nervous system.
  • Parasympathomimetics: These are drugs that mimic the effects of the parasympathetic nervous system.

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