Sphere Fluidics
A biotechnology company specializing in single cell analysis
Sphere Fluidics is a biotechnology company that focuses on the development and commercialization of products and services for single cell analysis and characterization. The company is known for its innovative use of microfluidics and droplet technology to enable high-throughput screening and analysis of individual cells. Sphere Fluidics' technology is particularly useful in fields such as drug discovery, biopharmaceuticals, and synthetic biology.
History[edit]
Sphere Fluidics was founded in 2010 as a spin-out from the University of Cambridge. The company was established to commercialize novel microfluidic technologies developed by its founders. Since its inception, Sphere Fluidics has grown to become a leader in the field of single cell analysis, with a range of products and services that cater to various applications in the life sciences.
Technology[edit]
Sphere Fluidics' core technology is based on the use of microfluidic devices to create and manipulate picoliter-sized droplets. These droplets can encapsulate single cells, allowing for the isolation and analysis of individual cells in a high-throughput manner. The company's technology platform, known as Cyto-Mine, integrates single cell analysis, sorting, and dispensing into a single automated system.
Cyto-Mine[edit]
The Cyto-Mine platform is designed to streamline the process of single cell analysis and monoclonality assurance. It combines microfluidics, imaging, and sorting technologies to enable the rapid screening of millions of cells. This platform is particularly useful for applications such as antibody discovery, cell line development, and genomics.
Applications[edit]
Sphere Fluidics' technology is used in a variety of applications across the life sciences. Some of the key areas include:
- Drug Discovery: The ability to screen large libraries of compounds against individual cells allows for the identification of potential drug candidates with high specificity and efficacy.
- Biopharmaceuticals: Sphere Fluidics' technology aids in the development of biopharmaceuticals by enabling the rapid screening and selection of high-producing cell lines.
- Synthetic Biology: The company's microfluidic systems facilitate the engineering of microorganisms for the production of biofuels, chemicals, and other valuable products.
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